Tomoo Kishaba
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View article: Bronchopneumonia Radiating Across All Pulmonary Lobes From the Hilum Caused by Human Metapneumovirus
Bronchopneumonia Radiating Across All Pulmonary Lobes From the Hilum Caused by Human Metapneumovirus Open
This human metapneumovirus pneumonia case, mimicking bacterial pneumonia, exhibited distinct features, including contact with a cold patient and CT findings of multilobar airway‐centric opacities with bronchial wall thickening. Even if poi…
View article: Predictors of relapse of polymyositis/dermatomyositis associated interstitial lung disease
Predictors of relapse of polymyositis/dermatomyositis associated interstitial lung disease Open
Serum LDH and GGO may serve as predictors of relapse in PM/DM-associated ILD patients.
View article: Proposed Clinical Algorithm for Pleuroparenchymal Fibroelastosis (PPFE)
Proposed Clinical Algorithm for Pleuroparenchymal Fibroelastosis (PPFE) Open
Pleuroparenchymal fibroelastosis (PPFE) is characterized by fibrosis involving the pleura and subpleural lung parenchyma, predominantly in the upper lobes. As PPFE appears to occur in patients with heterogeneous etiologies, the disease cou…
View article: Effectiveness of primary series, first, and second booster vaccination of monovalent mRNA COVID-19 vaccines against symptomatic SARS-CoV-2 infections and severe diseases during the SARS-CoV-2 omicron BA.5 epidemic in Japan: vaccine effectiveness real-time surveillance for SARS-CoV-2 (VERSUS)
Effectiveness of primary series, first, and second booster vaccination of monovalent mRNA COVID-19 vaccines against symptomatic SARS-CoV-2 infections and severe diseases during the SARS-CoV-2 omicron BA.5 epidemic in Japan: vaccine effectiveness real-time surveillance for SARS-CoV-2 (VERSUS) Open
This study aimed to evaluate VE of primary, first, and second booster ancestral-strain monovalent mRNA COVID-19 vaccination against symptomatic infections and severe diseases in Japan. We conducted a test-negative case-control study. We in…
View article: A Case of Paraneoplastic Neurological Syndrome Leading to the Diagnosis of Large Cell Neuroendocrine Carcinoma From Opsoclonus-Myoclonus Syndrome
A Case of Paraneoplastic Neurological Syndrome Leading to the Diagnosis of Large Cell Neuroendocrine Carcinoma From Opsoclonus-Myoclonus Syndrome Open
Opsoclonus-myoclonus syndrome (OMS) is a rare neurological disorder characterized by myoclonus, ataxia, and tremors. It can be classified as neoplastic or idiopathic, with small cell lung cancer being commonly associated. Herein, we presen…
View article: ZLN005 improves the protective effect of mitochondrial function on alveolar epithelial cell aging by upregulating PGC-1α
ZLN005 improves the protective effect of mitochondrial function on alveolar epithelial cell aging by upregulating PGC-1α Open
These results provide preliminary insights into the potential clinical application of ZLN005 as a novel therapeutic agent for the treatment of IPF.
View article: Cohort study to evaluate prognostic factors in idiopathic pulmonary fibrosis patients introduced to oxygen therapy
Cohort study to evaluate prognostic factors in idiopathic pulmonary fibrosis patients introduced to oxygen therapy Open
While high-level evidence is lacking, numerous retrospective studies have depicted the value of supplemental oxygen in idiopathic pulmonary fibrosis (IPF) and other interstitial lung diseases, and its use should be encouraged where necessa…
View article: Early corticosteroid dose tapering in patients with acute exacerbation of idiopathic pulmonary fibrosis
Early corticosteroid dose tapering in patients with acute exacerbation of idiopathic pulmonary fibrosis Open
Background Although corticosteroid therapy with dose tapering is the most commonly used treatment for acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF), there is no consensus on the tapering regimen. This study aimed to investig…
View article: Skeletal muscle atrophy and short-term mortality in patients with acute exacerbation of idiopathic pulmonary fibrosis: An observational cohort study
Skeletal muscle atrophy and short-term mortality in patients with acute exacerbation of idiopathic pulmonary fibrosis: An observational cohort study Open
Skeletal muscle atrophy often complicates idiopathic pulmonary fibrosis (IPF). IPF patients frequently experience acute exacerbation (AE), but the association between skeletal muscle atrophy and mortality remains unknown in AE-IPF patients…
View article: Radiological findings in nontuberculous mycobacterial pulmonary diseases: A comparison between the Mycobacterium avium complex and the Mycobacterium abscessus complex
Radiological findings in nontuberculous mycobacterial pulmonary diseases: A comparison between the Mycobacterium avium complex and the Mycobacterium abscessus complex Open
The Mycobacterium abscessus complex (MABC) comprises rapidly growing mycobacteria and has received increasing attention recently, with an increasing number of associated infections reported worldwide. However, the clinical features of MABC…
View article: Anti-Inflammatory and/or Anti-Fibrotic Treatment of MPO-ANCA-Positive Interstitial Lung Disease: A Short Review
Anti-Inflammatory and/or Anti-Fibrotic Treatment of MPO-ANCA-Positive Interstitial Lung Disease: A Short Review Open
The presence of a lung lesion is common in microscopic polyangiitis (MPA), and interstitial lung disease (ILD) can lead to a poor prognosis. Although myeloperoxidase antineutrophil cytoplasmic antibodies (MPO-ANCA) are often present in pat…
View article: Prognostic implication of IgG4 and IgG1-positive cell infiltration in the lung in patients with idiopathic interstitial pneumonia
Prognostic implication of IgG4 and IgG1-positive cell infiltration in the lung in patients with idiopathic interstitial pneumonia Open
Immunoglobulin (Ig) G4-positive cells are rarely observed in the lungs of patients with idiopathic interstitial pneumonias (IIPs). IgG1 may be more pathogenic than IgG4, with IgG4 having both pathogenic and protective roles in IgG4-related…
View article: Bilateral massive pneumonia caused by human metapneumovirus mimicking Mycoplasma pneumoniae pneumonia
Bilateral massive pneumonia caused by human metapneumovirus mimicking Mycoplasma pneumoniae pneumonia Open
Human metapneumovirus can be detected in adult community-acquired pneumonia. The chest image in this case was too massive to suspect human metapneumovirus pneumonia and clinically indistinguishable from Mycoplasma pneumoniae pneumonia. Thi…
View article: Lung Rest with Femoro-Femoral Veno-Venous Extracorporeal Membrane Oxygenation for COVID-19 Severe Pneumonia with Pneumomediastinum
Lung Rest with Femoro-Femoral Veno-Venous Extracorporeal Membrane Oxygenation for COVID-19 Severe Pneumonia with Pneumomediastinum Open
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sometimes causes severe coronavirus disease 2019 (COVID-19) pneumonia. Here, we report the case of a 35-year-old man with obesity who showed severe respiratory failure from SARS-…
View article: The Accuracy of Japanese Administrative Data in Identifying Acute Exacerbation of Idiopathic Pulmonary Fibrosis
The Accuracy of Japanese Administrative Data in Identifying Acute Exacerbation of Idiopathic Pulmonary Fibrosis Open
The criteria derived in this study for identifying AE-IPF from Japanese administrative data show a fair PPV. Although these criteria should be carefully interpreted according to the target population, our findings could be utilized in futu…
View article: Systemic lupus erythematosus presenting with lymphoid interstitial pneumonia as an initial manifestation
Systemic lupus erythematosus presenting with lymphoid interstitial pneumonia as an initial manifestation Open
A 25-year-old woman with an extensive travel history developed chronic cough and multiple lung nodules. The lung biopsy revealed lymphoid interstitial pneumonia. The patient later developed cervical lymphadenopathy, arthritis and livedo re…
View article: Community-acquired Respiratory Virus Cases Mimic COVID-19 on Lung Computed Tomography
Community-acquired Respiratory Virus Cases Mimic COVID-19 on Lung Computed Tomography Open
We herein report four patients with community-acquired respiratory virus (CRV) infection. Although they had no history of contact with any individual with coronavirus disease 2019 (COVID-19), they were suspected of having COVID-19 based on…
View article: Radiological and Physiological Predictors of IPF Mortality
Radiological and Physiological Predictors of IPF Mortality Open
Background and Objectives: Idiopathic pulmonary fibrosis (IPF) has a variable clinical course, which ranges from being asymptomatic to progressive respiratory failure. The purpose of this study was to evaluate the novel clinical parameters…
View article: Decision-Making Strategy for the Treatment of Rheumatoid Arthritis-Associated Interstitial Lung Disease (RA-ILD)
Decision-Making Strategy for the Treatment of Rheumatoid Arthritis-Associated Interstitial Lung Disease (RA-ILD) Open
Rheumatoid arthritis (RA) is a common type of autoimmune arthritis. Patient clinical outcomes might be influenced by numerous respiratory diseases, but interstitial lung disease (ILD) is the most important comorbidity. RA-associated ILD (R…
View article: The accuracy of Japanese administrative data in identifying acute exacerbation of idiopathic pulmonary fibrosis
The accuracy of Japanese administrative data in identifying acute exacerbation of idiopathic pulmonary fibrosis Open
Background This study aimed to develop criteria for identifying patients with acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) from Japanese administrative data and validate the pre-existing criteria. Methods This retrospective…
View article: Soft Tissue Thickness for Idiopathic Pulmonary Fibrosis
Soft Tissue Thickness for Idiopathic Pulmonary Fibrosis Open
Rationale: Idiopathic Pulmonary Fibrosis (IPF) is one of the representative progressive fibrosing interstitial lung disease.Regarding predictors of mortality of IPF, several parameters such as Krebs von den Lungen-6 (KL-6), forced vital ca…
View article: Alveolar Epithelial Denudation Is a Major Factor in the Pathogenesis of Pleuroparenchymal Fibroelastosis
Alveolar Epithelial Denudation Is a Major Factor in the Pathogenesis of Pleuroparenchymal Fibroelastosis Open
The pathogenesis of pleuroparenchymal fibroelastosis (PPFE), a rare interstitial lung disease, remains unclear. Based on previous reports and our experience, we hypothesized that alveolar epithelial denudation (AED) was involved in the pat…