Bentong Yu
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View article: CoreFormer high fidelity pulmonary nodule segmentation with structural core priors and geodesic implicit fields
CoreFormer high fidelity pulmonary nodule segmentation with structural core priors and geodesic implicit fields Open
Accurate delineation of pulmonary nodules in chest computed tomography (CT) is essential for early lung cancer diagnosis and treatment planning. However, voxel-wise segmentation methods often produce fragmented masks and inconsistent topol…
View article: Preoperative pembrolizumab (anti-PD-1 antibody) combined with chemoradiotherapy for esophageal squamous cell carcinoma: a phase 1/2 trial (PALACE-2)
Preoperative pembrolizumab (anti-PD-1 antibody) combined with chemoradiotherapy for esophageal squamous cell carcinoma: a phase 1/2 trial (PALACE-2) Open
The role of preoperative anti-PD-1 antibody (pembrolizumab) plus chemoradiotherapy (PPCT) in locally advanced, resectable esophageal squamous cell carcinoma (ESCC) is still unclear. We aimed to investigate the therapeutic effect and safety…
View article: Early detection of renal cell carcinoma: a novel cell-free DNA fragmentomics-based liquid biopsy assay
Early detection of renal cell carcinoma: a novel cell-free DNA fragmentomics-based liquid biopsy assay Open
The cfDNA fragmentomics-based liquid biopsy provides a promising, noninvasive, cost-effective, and accurate approach for RCC detection and management, substantiating its potential as a complementary tool to conventional diagnostic techniqu…
View article: Neoadjuvant Osimertinib for Resectable <i>EGFR</i> -Mutated Non–Small Cell Lung Cancer
Neoadjuvant Osimertinib for Resectable <i>EGFR</i> -Mutated Non–Small Cell Lung Cancer Open
PURPOSE Adjuvant osimertinib is the standard of care for patients with resected epidermal growth factor receptor ( EGFR )–mutated non–small cell lung cancer (NSCLC). Neoadjuvant treatment could improve surgical and long-term outcomes. METH…
View article: A multiomics dataset of paired CT image and plasma cell-free DNA end motif for patients with pulmonary nodules
A multiomics dataset of paired CT image and plasma cell-free DNA end motif for patients with pulmonary nodules Open
Diagnosing lung cancer at a curable stage offers the opportunity for a favorable prognosis. The emerging epigenomics analysis on plasma cell-free DNA (cfDNA), including 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) modification…
View article: Multidisciplinary international expert consensus on perioperative airway management
Multidisciplinary international expert consensus on perioperative airway management Open
This expert consensus provides a valuable reference for clinical practice. Further technological optimization and clinical research are needed to improve perioperative airway management.
View article: Robot-Assisted versus Video-Assisted Lobectomy for Early-Stage Non-Small Cell Lung Cancer (RAVAR): Study Protocol of a Prospective, Multicentre, Open-Label, Randomised Controlled Trial
Robot-Assisted versus Video-Assisted Lobectomy for Early-Stage Non-Small Cell Lung Cancer (RAVAR): Study Protocol of a Prospective, Multicentre, Open-Label, Randomised Controlled Trial Open
Background Video-assisted lobectomy (VAL) and robot-assisted lobectomy (RAL) are recommended standard treatments for early-stage non-small cell lung cancer (NSCLC). Nevertheless, comparisons of long-term survival between VAL and RAL are co…
View article: The establishment of an ex vivo lung perfusion rat model: insights from Jiangxi, China
The establishment of an ex vivo lung perfusion rat model: insights from Jiangxi, China Open
The scarcity of viable donor lungs is a formidable obstacle in lung transplantation (LTx) surgery. This issue significantly hinders the availability of this life-saving procedure for patients in need. To alleviate this shortage, researcher…
View article: Single-center experience of transitioning from video-assisted laparoscopic to robotic Heller myotomy with Dor fundoplication for esophageal motility disorders
Single-center experience of transitioning from video-assisted laparoscopic to robotic Heller myotomy with Dor fundoplication for esophageal motility disorders Open
Background Video-assisted laparoscopic Heller myotomy (LHM) has become the standard treatment option for achalasia. While robotic surgery offering some specific advantages such as better three-dimensional (3D) stereoscopic vision, hand-eye…
View article: Retraction: ET-1 promotes the growth and metastasis of esophageal squamous cell carcinoma via activating PI3K/Akt pathway
Retraction: ET-1 promotes the growth and metastasis of esophageal squamous cell carcinoma via activating PI3K/Akt pathway Open
[This retracts the article DOI: 10.21037/tcr.2020.04.26.].
View article: Impact of endoscopic thoracic R4 sympathicotomy combined with R3 ramicotomy for primary palmar hyperhidrosis
Impact of endoscopic thoracic R4 sympathicotomy combined with R3 ramicotomy for primary palmar hyperhidrosis Open
Background Endoscopic thoracoscopic sympathectomy (ETS) is the preferred method for treating primary palmar hyperhidrosis (PPH) that bears the risk of compensatory hyperhidrosis (CH) following surgery. The current study aims to evaluate th…
View article: Effect of pleural invasion on survival of patients with small cell lung cancer: Propensity score analysis and nomogram establishment based on the SEER database
Effect of pleural invasion on survival of patients with small cell lung cancer: Propensity score analysis and nomogram establishment based on the SEER database Open
Objectives Pleural invasion (PI) is identified as an adverse prognostic factor for non-small cell lung cancer (NSCLC), but its value in small cell lung cancer (SCLC) remains unclear. We aimed to evaluate the survival effect of PI on overal…
View article: Development and Validation of Nomograms to Predict Overall Survival and Cancer-Specific Survival for Non-Small Cell Lung Cancer with Chest Wall Invasion: A Population-Based Study
Development and Validation of Nomograms to Predict Overall Survival and Cancer-Specific Survival for Non-Small Cell Lung Cancer with Chest Wall Invasion: A Population-Based Study Open
Background: Chest wall invasion is a relatively kind of infrequent direct tumor extension in non-small cell lung cancer (NSCLC) with a poor survival outcome. Risk factors that impact overall survival (OS) and cancer-specific survival (CSS)…
View article: Deep learning for predicting major pathological response to neoadjuvant chemoimmunotherapy in non-small cell lung cancer: A multicentre study
Deep learning for predicting major pathological response to neoadjuvant chemoimmunotherapy in non-small cell lung cancer: A multicentre study Open
This study was supported by National Key Research and Development Program of China, China (2017YFA0205200); National Natural Science Foundation of China, China (91959126, 82022036, 91959130, 81971776, 81771924, 6202790004, 81930053, 919591…
View article: Expert consensus on indocyanine green fluorescence imaging for thoracoscopic lung resection (The Version 2022)
Expert consensus on indocyanine green fluorescence imaging for thoracoscopic lung resection (The Version 2022) Open
The use of the white-light thoracoscopy is hampered by the low contrast between oncologic margins and surrounding normal parenchyma. As a result, many patients with in situ or micro-infiltrating adenocarcinoma have to undergo lobectomy due…
View article: Feasibility of double sleeve lobectomy after neoadjuvant chemotherapy in patients with non-small-cell lung cancer
Feasibility of double sleeve lobectomy after neoadjuvant chemotherapy in patients with non-small-cell lung cancer Open
OBJECTIVES This study intends to appraise the feasibility of double sleeve lobectomy after neoadjuvant chemotherapy in central non-small-cell lung cancer with bronchovascular aggression. METHODS This retrospective study included non-small-…
View article: Multicenter, single-arm, phase II trial of camrelizumab and chemotherapy as neoadjuvant treatment for locally advanced esophageal squamous cell carcinoma
Multicenter, single-arm, phase II trial of camrelizumab and chemotherapy as neoadjuvant treatment for locally advanced esophageal squamous cell carcinoma Open
Background Camrelizumab and chemotherapy demonstrated durable antitumor activity with a manageable safety profile as first-line treatment in patients with advanced esophageal squamous cell carcinoma (ESCC). This study aimed to evaluate the…
View article: Implementation of artificial intelligence in the histological assessment of pulmonary subsolid nodules
Implementation of artificial intelligence in the histological assessment of pulmonary subsolid nodules Open
The AI diagnostic system achieved non-inferior performance to doctors, and will potentially improve diagnostic performance and efficiency in SSN evaluation.
View article: Chimeric Antigen Receptor T-Cell Therapy in Lung Cancer: Potential and Challenges
Chimeric Antigen Receptor T-Cell Therapy in Lung Cancer: Potential and Challenges Open
Chimeric antigen receptor T (CAR-T) cell therapy has exhibited a substantial clinical response in hematological malignancies, including B-cell leukemia, lymphoma, and multiple myeloma. Therefore, the feasibility of using CAR-T cells to tre…
View article: FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma
FAIM regulates autophagy through glutaminolysis in lung adenocarcinoma Open
Altered glutamine metabolism is an important aspect of cancer metabolic reprogramming. The GLS isoform GAC (glutaminase C), the rate-limiting enzyme in glutaminolysis, plays a vital role in cancer initiation and progression. Our previous s…