Tony Bewersdorff
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View article: <p>Amphiphilic nanogels: influence of surface hydrophobicity on protein corona, biocompatibility and cellular uptake</p>
Amphiphilic nanogels: influence of surface hydrophobicity on protein corona, biocompatibility and cellular uptake Open
Background and purpose: Nanogels (NGs) are promising drug delivery tools but are typically limited to hydrophilic drugs. Many potential new drugs are hydrophobic. Our study systematically investigates amphiphilic NGs with varying hydrophob…
View article: Amphiphilic nanogels: influence of surface hydrophobicity on protein corona, biocompatibility and cellular uptake
Amphiphilic nanogels: influence of surface hydrophobicity on protein corona, biocompatibility and cellular uptake Open
Tony Bewersdorff,1 Alexandra Gruber,2 Murat Eravci,1 Malti Dumbani,1 Daniel Klinger,2 Andrea Haase1 1German Federal Institute for Risk Assessment (BfR), Department of Chemical and Product Safety, Berlin, Germany; 2Freie Universität Berlin,…
View article: The influence of surface charge on serum protein interaction and cellular uptake: studies with dendritic polyglycerols and dendritic polyglycerol-coated gold nanoparticles
The influence of surface charge on serum protein interaction and cellular uptake: studies with dendritic polyglycerols and dendritic polyglycerol-coated gold nanoparticles Open
Nanoparticles (NPs) have gained huge interest in the medical field, in particular for drug delivery purposes. However, binding of proteins often leads to fast NP uptake and rapid clearance, thereby hampering medical applications. Thus, it …