Torben Meiners
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Dysfunctional copper homeostasis in Caenorhabditis elegans affects genomic and neuronal stability Open
While copper (Cu) is an essential trace element for biological systems due to its redox properties, excess levels may lead to adverse effects partly due to overproduction of reactive species. Thus, a tightly regulated Cu homeostasis is cru…
Copper-mediated neurotoxicity and genetic vulnerability in the background of neurodegenerative diseases in <i>C. elegans</i> Open
The mechanisms associated with neurodegenerative diseases, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), have yet to be fully characterized, and genetic as well as environmental factors in their disease etiology are undera…