Torben Seested
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View article: Elucidating the Mechanism of Absorption of Fast-Acting Insulin Aspart: The Role of Niacinamide
Elucidating the Mechanism of Absorption of Fast-Acting Insulin Aspart: The Role of Niacinamide Open
Niacinamide mediates the acceleration of initial insulin aspart absorption, and the mechanism of action appears to be multifaceted. Niacinamide increases the initial abundance of insulin aspart monomers and transport of insulin aspart afte…
View article: Delayed insulin absorption correlates with alterations in subcutaneous depot kinetics in rats with diet‐induced obesity
Delayed insulin absorption correlates with alterations in subcutaneous depot kinetics in rats with diet‐induced obesity Open
Summary Objective Obesity is associated with delayed insulin absorption upon subcutaneous (s.c.) dosing in humans. The aim of this study was to investigate whether alterations in depot structure and kinetics of the s.c. injection depot con…
View article: Factors Affecting the Absorption of Subcutaneously Administered Insulin: Effect on Variability
Factors Affecting the Absorption of Subcutaneously Administered Insulin: Effect on Variability Open
Variability in the effect of subcutaneously administered insulin represents a major challenge in insulin therapy where precise dosing is required in order to achieve targeted glucose levels. Since this variability is largely influenced by …