Toshiyuki Yamada
YOU?
Author Swipe
View article: Opsin 3-mediated regulation of blue light-induced β-hexosaminidase release from mast cells
Opsin 3-mediated regulation of blue light-induced β-hexosaminidase release from mast cells Open
The human body is constantly exposed to light from the environment, and intense light is a source of skin inflammation. Although cellular responses to high-energy ultraviolet light have long been reported, the photoresponsive mechanism occ…
View article: Safety and Efficacy of Low-Dose Triamcinolone Injection without Injection Frequency Limitation for Trigger Finger
Safety and Efficacy of Low-Dose Triamcinolone Injection without Injection Frequency Limitation for Trigger Finger Open
Therapeutic Ⅳ.
View article: Electrolytic-reduction ion water protects keratinocytes from hydrogen peroxide through radical scavenging activity and induction of AQP3 expression
Electrolytic-reduction ion water protects keratinocytes from hydrogen peroxide through radical scavenging activity and induction of AQP3 expression Open
Skin exposed to ultraviolet light produces hydrogen peroxide (H2O2) and reactive oxygen species (ROS) that cause protein denaturation and other disorders. We investigated whether electrolytic-reduction ion water (ERI)…
View article: Relationship of thyroid function with renal hemodynamics and cholesterol metabolism in proteinuric kidney disease: A retrospective pilot study
Relationship of thyroid function with renal hemodynamics and cholesterol metabolism in proteinuric kidney disease: A retrospective pilot study Open
Back ground. Massive proteinuria and hypothyroidism are respectively reported to influence renal hemodynamic and hypercholesterolemia. However, the relationship of proteinuria-associated thyroid function with renal hemodynamics and cholest…
View article: Issue Information
Issue Information Open
Study of unilateral cleft lip and palate using different impressions techniques on the same patient. A. Conventional impression technique, B. Impression technique using intraoral scanner, C. Superimposed results of impression methods showi…
View article: Membrane translocation of vinculin after UVA exposure facilitates melanosome trafficking
Membrane translocation of vinculin after UVA exposure facilitates melanosome trafficking Open
Skin pigmentation is among the defenses against ultraviolet (UV) radiation. During formation of skin pigmentation, melanosomes that are transported to the cell membrane and released are internalized by keratinocytes. We here examined wheth…
View article: Effects of oral cystine and glutamine on exercise-induced changes in gastrointestinal permeability and damage markers in young men
Effects of oral cystine and glutamine on exercise-induced changes in gastrointestinal permeability and damage markers in young men Open
Purpose Although acute prolonged strenuous exercise has been shown to increase markers of gastrointestinal permeability and damage, little is known regarding the efficacy of nutritional supplement interventions on the attenuation of exerci…
View article: Calcium phosphate microcrystals in the renal tubular fluid accelerate chronic kidney disease progression
Calcium phosphate microcrystals in the renal tubular fluid accelerate chronic kidney disease progression Open
The Western pattern diet is rich not only in fat and calories but also in phosphate. The negative effects of excessive fat and calorie intake on health are widely known, but the potential harms of excessive phosphate intake are poorly reco…
View article: Correction to: Precocious maturation in male tiger pufferfish Takifugu rubripes: genetics and endocrinology
Correction to: Precocious maturation in male tiger pufferfish Takifugu rubripes: genetics and endocrinology Open
A correction to this paper has been published: https://doi.org/10.1007/s12562-021-01505-w
View article: Correction to: Prevention of hypermelanosis by rearing Japanese flounder Paralichthys olivaceus in net‑lined tanks
Correction to: Prevention of hypermelanosis by rearing Japanese flounder Paralichthys olivaceus in net‑lined tanks Open
A correction to this paper has been published: https://doi.org/10.1007/s12562-021-01504-x
View article: Genetic Dissection of a Precocious Phenotype in Male Tiger Pufferfish (Takifugu rubripes) using Genotyping by Random Amplicon Sequencing, Direct (GRAS-Di)
Genetic Dissection of a Precocious Phenotype in Male Tiger Pufferfish (Takifugu rubripes) using Genotyping by Random Amplicon Sequencing, Direct (GRAS-Di) Open
The novel non-targeted PCR-based genotyping system, namely Genotyping by Random Amplicon Sequencing, Direct (GRAS-Di), is characterized by the simplicity in library construction and robustness against DNA degradation and is expected to fac…
View article: Using the neutrophil-to-lymphocyte ratio to estimate the severity of coronavirus disease 2019
Using the neutrophil-to-lymphocyte ratio to estimate the severity of coronavirus disease 2019 Open
View article: The Effect of Leucine-Enriched Essential Amino Acid Supplementation on Anabolic and Catabolic Signaling in Human Skeletal Muscle after Acute Resistance Exercise: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Comparison Trial
The Effect of Leucine-Enriched Essential Amino Acid Supplementation on Anabolic and Catabolic Signaling in Human Skeletal Muscle after Acute Resistance Exercise: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Comparison Trial Open
Resistance exercise transiently activates anabolic and catabolic systems in skeletal muscle. Leucine-enriched essential amino acids (LEAAs) are reported to stimulate the muscle anabolic response at a lower dose than whey protein. However, …
View article: Vinculin Migrates to the Cell Membrane of Melanocytes After UVB Irradiation
Vinculin Migrates to the Cell Membrane of Melanocytes After UVB Irradiation Open
Melanocytes increase melanin production upon exposure to ultraviolet rays (UV) as a defense mechanism. Melanin synthesis in melanocytes is regulated by bioactive factors produced and secreted by keratinocytes. In addition, melanocytes tran…
View article: Precocious maturation in male tiger pufferfish Takifugu rubripes: genetics and endocrinology
Precocious maturation in male tiger pufferfish Takifugu rubripes: genetics and endocrinology Open
Testes of the tiger pufferfish Takifugu rubripes are a delicacy in Japan, and selective breeding for a male precocious phenotype, i.e., with early initiation of testes development, is desirable. However, it is unknown if precocious gonad d…
View article: Prevention of hypermelanosis by rearing Japanese flounder Paralichthys olivaceus in net-lined tanks
Prevention of hypermelanosis by rearing Japanese flounder Paralichthys olivaceus in net-lined tanks Open
In artificially reared flatfish, especially the Japanese flounder Paralichthys olivaceus , pigmented skin (hypermelanosis) frequently appears on the fish’s blind side after normal metamorphosis. As no practical prevention method has yet be…
View article: Delay in hepatocyte proliferation and prostaglandin D2 synthase expression for cholestasis due to endotoxin during partial hepatectomy in rats
Delay in hepatocyte proliferation and prostaglandin D2 synthase expression for cholestasis due to endotoxin during partial hepatectomy in rats Open
Infection is a frequent complication of liver transplantation or partial hepatectomy (PH) and sometimes results in cholestasis. We examined factors involved in infection‑induced cholestasis after PH, employing a rat PH model and lipopolysa…
View article: A Questionnaire Survey on Extracorporeal Membrane Oxygenation Targeting Under-Forty Cardiovascular Surgeons No.8
A Questionnaire Survey on Extracorporeal Membrane Oxygenation Targeting Under-Forty Cardiovascular Surgeons No.8 Open
われわれ心臓血管外科医が当たり前に行っている基本的手技は，施設間の差異が大きいにもかかわらず，基本的であるがゆえに議論されることが少ない．今回われわれは，ECMO/PCPSのテーマで全国のU-40幹事にアンケート調査を行い，53名からの返答を得た．アンケート結果を報告する．
View article: Hair keratin KRT81 is expressed in normal and breast cancer cells and contributes to their invasiveness
Hair keratin KRT81 is expressed in normal and breast cancer cells and contributes to their invasiveness Open
Keratins are fibrous proteins. Hair keratins constitute hard structures such as the hair and nails, and cytokeratins have been used as markers of breast carcinoma. However, the expression and function of full-size hair keratin genes have n…
View article: The significance which conducts a serum protein fraction in the hospital laboratory
The significance which conducts a serum protein fraction in the hospital laboratory Open
血清蛋白分画検査は，血清蛋白異常症のスクリーニング検査として広く用いられており，特に多発性骨髄腫の診断および治療効果の判定に欠かせないM蛋白の検出方法である．血清蛋白分画を院内で実施する最大の意義は，重要な所見を発見し，その病態を把握したうえでいち早く依頼医に報告できることである．当院における取り組みとしては以下のようなものがある．第一に，悪性M蛋白等異常所見を認めた患者においては，検査技師がカルテを閲覧し，検査目的や他の検査所見を参考に，疑われる病態を考察する．第二に特徴…
View article: Analysis of cryoglobulin for providing valuable reports from clinical laboratory
Analysis of cryoglobulin for providing valuable reports from clinical laboratory Open
温度依存性蛋白とは,反応温度により性状が変化する異常蛋白で,主として免疫グロブリンである.特に臨床検査室でよく遭遇するクリオグロブリンは,室温以下で白濁し,37°Cで再溶解する免疫グロブリンであり,免疫化学的検査において異常反応を起こすことがある.臨床的には,原因不明のレイノー現象,紫斑性血管炎,動静脈炎,腎症および原因不明の過粘稠症候群に関連する.クリオグロブリンには3つの型があり,I型:M蛋白からなる,II型:M蛋白とポリクローナル免疫グロブリンの混合型,III型:ポリ…
View article: H-2Aロケット試験機1号機SRB-Aフライト結果
H-2Aロケット試験機1号機SRB-Aフライト結果 Open
H-2A Test Flight #1 was launched successfully at 16:00, August 29, 2001 (JST) from Tanegashima Space Center, NASDA. This paper describes the overview on the SRB-A flight results evaluation and design improvements toward the next flight, Te…
View article: Fatty acid synthase-positive hepatocytes and subsequent steatosis in rat livers by irinotecan
Fatty acid synthase-positive hepatocytes and subsequent steatosis in rat livers by irinotecan Open
Using a rat model, we investigated factors contributing to the pathogenesis of irinotecan-associated fatty liver disease. Male Sprague-Dawley rats were administered 200 mg/kg irinotecan by intraperitoneal injection on days 1-4, but not on …
View article: A Rare Complication after Tricuspid Annuloplasty
A Rare Complication after Tricuspid Annuloplasty Open
症例は83歳女性．僧帽弁閉鎖不全症（mitral valve regurgitation ; MR）による心不全のため前医より紹介された．僧帽弁置換術（mitral valve replacement ; MVR），三尖弁輪形成術（tricuspid annuloplasty ; TAP）を施行した．術直後は良好な経過であった．術後7日目から心不全症状を認め，心エコーで重症大動脈弁閉鎖不全（aortic valve regurgitation ; AR）を指摘された．心不全…
View article: Occurrence of the Bluefin Tuna Blood Fluke <i>Cardicola opisthorchis</i> in the Intermediate Host <i>Terebella</i> sp.
Occurrence of the Bluefin Tuna Blood Fluke <i>Cardicola opisthorchis</i> in the Intermediate Host <i>Terebella</i> sp. Open
The blood fluke Cardicola opisthorchis (Trematoda: Aporocotylidae) is a significant pathogen of cultured Pacific bluefin tuna Thunnus orientalis in Japan. We conducted monthly surveys of the intermediate polychaete host Terebella sp. (Poly…
View article: Possible relationship between the heart rates and serum amyloid A in a hyperglycemic population
Possible relationship between the heart rates and serum amyloid A in a hyperglycemic population Open
Hyperglycemia predicts cardiovascular disease (CVD)-related outcomes. The resting heart rates (HRs) and serum amyloid A (SAA), an inflammatory marker, are respectively factors associated with CVD-related outcomes; however, little is known …
View article: Eliminating the EPP toward a Principled Explanation : Labeling in the ECM Construction
Eliminating the EPP toward a Principled Explanation : Labeling in the ECM Construction Open