Tracie R. Baker
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View article: Lead as a Reproductive Endocrine Disruptor in Aquatic Species and Agricultural Livestock
Lead as a Reproductive Endocrine Disruptor in Aquatic Species and Agricultural Livestock Open
Lead (Pb) is a naturally occurring metal that is environmentally ubiquitous due to industrial activities, such as mining, smelting, and fossil fuel combustion. Exposure to Pb adversely affects the central nervous system, gastrointestinal t…
View article: Multi- and Transgenerational Histological and Transcriptomic Outcomes of Developmental TCDD Exposure in Zebrafish (Danio rerio) Ovary
Multi- and Transgenerational Histological and Transcriptomic Outcomes of Developmental TCDD Exposure in Zebrafish (Danio rerio) Ovary Open
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) exposure has long been associated with reproductive dysfunction in males and females even at miniscule levels, which can persist across generations. Given the continued industrial use and detectio…
View article: Environmental Exposure to Per- and Polyfluorylalkyl Substances (PFASs) and Reproductive Outcomes in the General Population: A Systematic Review of Epidemiological Studies
Environmental Exposure to Per- and Polyfluorylalkyl Substances (PFASs) and Reproductive Outcomes in the General Population: A Systematic Review of Epidemiological Studies Open
This Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) systematic review synthesized effects of background levels of per- and polyfluorylalkyl substance (PFAS) levels on reproductive health outcomes in the general…
View article: Implications of Lead (Pb)-Induced Transcriptomic and Phenotypic Alterations in the Aged Zebrafish (Danio rerio)
Implications of Lead (Pb)-Induced Transcriptomic and Phenotypic Alterations in the Aged Zebrafish (Danio rerio) Open
Lead (Pb) is a well-known neurotoxin with established adverse effects on the neurological functions of children and younger adults, including motor, learning, and memory abilities. However, its potential impact on older adults has received…
View article: Status of single-cell RNA sequencing for reproductive toxicology in zebrafish and the transcriptomic trade-off
Status of single-cell RNA sequencing for reproductive toxicology in zebrafish and the transcriptomic trade-off Open
View article: Juvenile exposure to low-level 2,3,7,8-tetrachlorodibenzo-<i>p</i>-dioxin (TCDD) alters behavior and longitudinal morphometrics in zebrafish and F<sub>1</sub> offspring
Juvenile exposure to low-level 2,3,7,8-tetrachlorodibenzo-<i>p</i>-dioxin (TCDD) alters behavior and longitudinal morphometrics in zebrafish and F<sub>1</sub> offspring Open
Exposure to 2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD), an environmental endocrine disruptor and model AhR agonist, is linked to skeletal abnormalities, cardiac edema, stunted growth rate, altered metabolism, and neurobehavioral deficits…
View article: Adult-Onset Transcriptomic Effects of Developmental Exposure to Benzene in Zebrafish (Danio rerio): Evaluating a Volatile Organic Compound of Concern
Adult-Onset Transcriptomic Effects of Developmental Exposure to Benzene in Zebrafish (Danio rerio): Evaluating a Volatile Organic Compound of Concern Open
Urban environments are afflicted by mixtures of anthropogenic volatile organic compounds (VOCs). VOC sources that drive human exposure include vehicle exhaust, industrial emissions, and oil spillage. The highly volatile VOC benzene has bee…
View article: Sewage Transport Volumes and Physical Degradation Rates of Personal Care Wipes
Sewage Transport Volumes and Physical Degradation Rates of Personal Care Wipes Open
As personal care wipes become increasingly popular, inappropriate disposal to the sewage system is raising significant environmental and economic concerns. Many common brands, while marketed as “flushable,” do not degrade appreciably in th…
View article: Evaluating Phenotypic and Transcriptomic Responses Induced by Low-Level VOCs in Zebrafish: Benzene as an Example
Evaluating Phenotypic and Transcriptomic Responses Induced by Low-Level VOCs in Zebrafish: Benzene as an Example Open
Urban environments are plagued by complex mixtures of anthropogenic volatile organic compounds (VOCs), such as mixtures of benzene, toluene, ethylene, and xylene (BTEX). Sources of BTEX that drive human exposure include vehicle exhaust, in…
View article: Insight into 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced disruption of zebrafish spermatogenesis via single cell RNA-seq
Insight into 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced disruption of zebrafish spermatogenesis via single cell RNA-seq Open
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a potent and environmentally persistent endocrine disrupting chemical. Our previous work demonstrated the latent reproductive maladies of early-life TCDD exposure in zebrafish. Zebrafish acutel…
View article: Multi- and Transgenerational Effects of Developmental Exposure to Environmental Levels of PFAS and PFAS Mixture in Zebrafish (Danio rerio)
Multi- and Transgenerational Effects of Developmental Exposure to Environmental Levels of PFAS and PFAS Mixture in Zebrafish (Danio rerio) Open
Per- and polyfluoroalkyl substances (PFASs) are ubiquitous in the environment and are tied to myriad health effects. Despite the phasing out of the manufacturing of two types of PFASs (perfluorosulfonic acid (PFOS) and perfluorooctanoic ac…
View article: Comparative Toxicotranscriptomics of Single Cell RNA-Seq and Conventional RNA-Seq in TCDD-Exposed Testicular Tissue
Comparative Toxicotranscriptomics of Single Cell RNA-Seq and Conventional RNA-Seq in TCDD-Exposed Testicular Tissue Open
In this report, we compare the outcomes and limitations of two methods of transcriptomic inquiry on adult zebrafish testes exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) during sexual differentiation: conventional or bulk RNA-seq (b…
View article: <scp>Point‐of‐use</scp> carbon‐block drinking water filters change gut microbiome of larval zebrafish
<span>Point‐of‐use</span> carbon‐block drinking water filters change gut microbiome of larval zebrafish Open
Summary Activated carbon block (ACB) point‐of‐use (PoU) drinking water filters can change the bacterial composition in drinking water. Consuming ACB PoU filtered water may also influence gut microbiomes. This study uses the zebrafish model…
View article: Caring for Partners of a Dismal Dance: Listening for Spiritual Suffering in Family Caregivers of Patients with Huntington's Chorea (FR265)
Caring for Partners of a Dismal Dance: Listening for Spiritual Suffering in Family Caregivers of Patients with Huntington's Chorea (FR265) Open
View article: Developmental Phenotypic and Transcriptomic Effects of Exposure to Nanomolar Levels of 4-Nonylphenol, Triclosan, and Triclocarban in Zebrafish (Danio rerio)
Developmental Phenotypic and Transcriptomic Effects of Exposure to Nanomolar Levels of 4-Nonylphenol, Triclosan, and Triclocarban in Zebrafish (Danio rerio) Open
Triclosan, triclocarban and 4-nonylphenol are all chemicals of emerging concern found in a wide variety of consumer products that have exhibited a wide range of endocrine-disrupting effects and are present in increasing amounts in groundwa…
View article: Phenotypic and transcriptomic effects of developmental exposure to nanomolar levels of pesticides in zebrafish
Phenotypic and transcriptomic effects of developmental exposure to nanomolar levels of pesticides in zebrafish Open
This study investigates the pesticides atrazine, chlorpyrifos, and dieldrin for endocrine disrupting, phenotypic, and neurobehavioral effects. Zebrafish embryos were exposed to various environmentally relevant concentrations of pesticides …
View article: Developmental phenotypic and transcriptomic effects of exposure to nanomolar levels of metformin in zebrafish
Developmental phenotypic and transcriptomic effects of exposure to nanomolar levels of metformin in zebrafish Open
View article: Adipocyte-driven unfolded protein response is a shared transcriptomic signature of metastatic prostate carcinoma cells
Adipocyte-driven unfolded protein response is a shared transcriptomic signature of metastatic prostate carcinoma cells Open
View article: A Review of Volatile Organic Compound Contamination in Post-Industrial Urban Centers: Reproductive Health Implications Using a Detroit Lens
A Review of Volatile Organic Compound Contamination in Post-Industrial Urban Centers: Reproductive Health Implications Using a Detroit Lens Open
Volatile organic compounds (VOCs) are a group of aromatic or chlorinated organic chemicals commonly found in manufactured products that have high vapor pressure, and thus vaporize readily at room temperature. While airshed VOCs are well st…
View article: Cisplatin-induced hair cell loss in zebrafish neuromasts is accompanied by protein nitration and Lmo4 degradation
Cisplatin-induced hair cell loss in zebrafish neuromasts is accompanied by protein nitration and Lmo4 degradation Open
View article: The phenotypic and transcriptomic effects of developmental exposure to nanomolar levels of estrone and bisphenol A in zebrafish
The phenotypic and transcriptomic effects of developmental exposure to nanomolar levels of estrone and bisphenol A in zebrafish Open
View article: Nanoplastics impact the zebrafish (Danio rerio) transcriptome: Associated developmental and neurobehavioral consequences
Nanoplastics impact the zebrafish (Danio rerio) transcriptome: Associated developmental and neurobehavioral consequences Open
View article: Removal efficiency of micro- and nanoplastics (180 nm–125 μm) during drinking water treatment
Removal efficiency of micro- and nanoplastics (180 nm–125 μm) during drinking water treatment Open
View article: TCDD-induced multi- and transgenerational changes in the methylome of male zebrafish gonads
TCDD-induced multi- and transgenerational changes in the methylome of male zebrafish gonads Open
The legacy endocrine disrupting chemical and aryl hydrocarbon receptor agonist, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), is produced as a byproduct of industrial processes and causes adverse health effects ranging from skin irritation t…
View article: Developmental exposure to Pb2+ induces transgenerational changes to zebrafish brain transcriptome
Developmental exposure to Pb2+ induces transgenerational changes to zebrafish brain transcriptome Open
View article: Sox9 in mouse urogenital sinus epithelium mediates elongation of prostatic buds and expression of genes involved in epithelial cell migration
Sox9 in mouse urogenital sinus epithelium mediates elongation of prostatic buds and expression of genes involved in epithelial cell migration Open
View article: Exposure of Larval Zebrafish to the Insecticide Propoxur Induced Developmental Delays that Correlate with Behavioral Abnormalities and Altered Expression of hspb9 and hspb11
Exposure of Larval Zebrafish to the Insecticide Propoxur Induced Developmental Delays that Correlate with Behavioral Abnormalities and Altered Expression of hspb9 and hspb11 Open
Recent studies suggest that organophosphates and carbamates affect human fetal development, resulting in neurological and growth impairment. However, these studies are conflicting and the extent of adverse effects due to pesticide exposure…
View article: Environmental Contaminants in the Lake Huron to Erie Corridor: Effects on Zebrafish
Environmental Contaminants in the Lake Huron to Erie Corridor: Effects on Zebrafish Open
Contaminants of emerging concern (CECs) and endocrine-disrupting chemicals (EDCs) include pharmaceutical, personal care, agricultural, and industrial byproducts that enter waterways via effluent, runoff, aging infrastructure, and inadequat…
View article: Management of Multiple Protozoan Ectoparasites in a Research Colony of Axolotls (<i>Ambystoma mexicanum</i>)
Management of Multiple Protozoan Ectoparasites in a Research Colony of Axolotls (<i>Ambystoma mexicanum</i>) Open
Axolotls (Ambystoma mexicanum) from a research colony presented with multifocal, white chalky to gray skin lesions, a diffuse whitish to blue hue to the integument, and friable gill filaments. Skin scrapings and wet mounts revealed …
View article: Developmental Dioxin Exposure Alters the Methylome of Adult Male Zebrafish Gonads
Developmental Dioxin Exposure Alters the Methylome of Adult Male Zebrafish Gonads Open
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a persistent environmental toxicant and endocrine disrupting compound with reproductive and developmental effects in humans and model organisms, including zebrafish. Our previous microar…