Tracy E. Campbell
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View article: Human Papillomavirus T-Cell Cross-reactivity in Cervical Cancer
Human Papillomavirus T-Cell Cross-reactivity in Cervical Cancer Open
Cervical cancers that tested positive for HPV-18 were common in this study and may be common in other US clinical trial populations. Results showed that HPV-16/HPV-18 intergenotype T-cell cross-reactivity of T cells from HPV-16-positive an…
View article: Engineered T cells targeting E7 mediate regression of human papillomavirus cancers in a murine model
Engineered T cells targeting E7 mediate regression of human papillomavirus cancers in a murine model Open
T cell receptor (TCR) T cell therapy is a promising cancer treatment modality. However, its successful development for epithelial cancers may depend on the identification of high-avidity TCRs directed against tumor-restricted target antige…
View article: Complete Regression of Metastatic Cervical Cancer After Treatment With Human Papillomavirus–Targeted Tumor-Infiltrating T Cells
Complete Regression of Metastatic Cervical Cancer After Treatment With Human Papillomavirus–Targeted Tumor-Infiltrating T Cells Open
Purpose Metastatic cervical cancer is a prototypical chemotherapy-refractory epithelial malignancy for which better treatments are needed. Adoptive T-cell therapy (ACT) is emerging as a promising cancer treatment, but its study in epitheli…