Phi-Long Tran
YOU?
Author Swipe
View article: RET Receptor Tyrosine Kinase Promotes Breast Cancer Metastasis to the Brain and RET Inhibitors Pralsetinib and Selpercatinib Suppress Breast Cancer Brain Metastases
RET Receptor Tyrosine Kinase Promotes Breast Cancer Metastasis to the Brain and RET Inhibitors Pralsetinib and Selpercatinib Suppress Breast Cancer Brain Metastases Open
Patients with breast cancer brain metastases (BCBM) exhibit dismal prognosis, largely due to the insufficient biological understanding of BCBM and the scarcity of therapeutics that can penetrate the blood-brain barrier. This study was focu…
View article: BSBM-06 A NOVEL THERAPEUTIC STRATEGY FOR THE TREATMENT OF BREAST CANCER BRAIN METASTASIS BY SELECTIVELY TARGETING RET USING FDA-APPROVED DRUGS.
BSBM-06 A NOVEL THERAPEUTIC STRATEGY FOR THE TREATMENT OF BREAST CANCER BRAIN METASTASIS BY SELECTIVELY TARGETING RET USING FDA-APPROVED DRUGS. Open
Breast cancer brain metastasis (BCBM) constitutes 10-30% of metastatic breast cancer. Clinical studies reported that BCBM patients typically have shorter survival times (6-12 months), compared to patients with lung, liver, or bone metastas…
View article: PRCA-08 A NOVEL BBB-PERMEABLE ANALOG FOR BREAST CANCER BRAIN METASTASES
PRCA-08 A NOVEL BBB-PERMEABLE ANALOG FOR BREAST CANCER BRAIN METASTASES Open
Breast cancer brain metastasis (BCBM) accounts for 10-30% of the breast cancer metastatic burden and is associated with dismal prognoses, having a median survival time of 7.9 months. The poor outcomes stem from limited understanding of BCB…
View article: SDCBP/Syntenin-1 stabilizes BACH1 by disassembling the SCFFBXO22–BACH1 complex in triple-negative breast cancer
SDCBP/Syntenin-1 stabilizes BACH1 by disassembling the SCFFBXO22–BACH1 complex in triple-negative breast cancer Open
View article: Mesenchymal Stem Cells Carrying Viral Fusogenic Protein p14 to Treat Solid Tumors by Inducing Cell–Cell Fusion and Immune Activation
Mesenchymal Stem Cells Carrying Viral Fusogenic Protein p14 to Treat Solid Tumors by Inducing Cell–Cell Fusion and Immune Activation Open
Background: Chimeric antigen receptor (CAR)-based immune cell therapies attack neighboring cancer cells after receptor recognition but are unable to directly affect distant tumor cells. This limitation may contribute to their inefficiency …
View article: Protective effects of extract of Cleistocalyx operculatus flower buds and its isolated major constituent against LPS-induced endotoxic shock by activating the Nrf2/HO-1 pathway
Protective effects of extract of Cleistocalyx operculatus flower buds and its isolated major constituent against LPS-induced endotoxic shock by activating the Nrf2/HO-1 pathway Open
The flower buds of Cleistocalyx operculatus are used as an important ingredient in herbal tea and herbal products in several tropical countries. However, their protective effects and underlying mechanisms on lipopolysaccharide (LPS)-induce…
View article: Anti-inflammatory effects of alkaloid enriched extract from roots of Eurycoma longifolia Jack
Anti-inflammatory effects of alkaloid enriched extract from roots of Eurycoma longifolia Jack Open
Objective: To examine the in vitro and in vivo anti-inflammatory effects of the alkaloid enriched extract (ELA) from the roots of Eurycoma longifolia. Methods: The in vitro antiinflammatory effects of ELA were evaluated by examining its in…
View article: CIRBP protects H9C2 cells against myocardial ischemia through inhibition of NF-κB pathway
CIRBP protects H9C2 cells against myocardial ischemia through inhibition of NF-κB pathway Open
Myocardial ischemia is a major cause of death and remains a disease with extremely deficient clinical therapies and a major problem worldwide. Cold inducible RNA-binding protein (CIRBP) is reported to be involved in multiple pathological p…
View article: CIRBP protects H9C2 cells against myocardial ischemia through inhibition of NF-κB pathway
CIRBP protects H9C2 cells against myocardial ischemia through inhibition of NF-κB pathway Open
Myocardial ischemia is a major cause of death and remains a disease with extremely deficient clinical therapies and a major problem worldwide. Cold inducible RNA-binding protein (CIRBP) is reported to be involved in multiple pathological p…