Mary Nguyen
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View article: SUN-818 AI- Chatbots: Do they help our obese teenaged Type 2 DM patients?
SUN-818 AI- Chatbots: Do they help our obese teenaged Type 2 DM patients? Open
Disclosure: G. Wu: None. I. Chim: None. M. Nguyen: None. B. Hoang: None. N. Mansubi: None. V.V. Toram: None. R. Toram: None. A. Madala: None. Background: Many patients ask healthcare questions to AI-mediated chatbots/LLMs, such as ChatGPT,…
View article: Healthcare, smartphones, and the carbon footprint
Healthcare, smartphones, and the carbon footprint Open
Smartphones are widely used by physicians and patients. The carbon footprint of healthcare devices is poorly documented. Physicians report an average daily smartphone usage of 1 – 5 h for activities, such as reviewing diagnostic info…
View article: Clinical response to azacitidine in MDS is associated with distinct DNA methylation changes in HSPCs
Clinical response to azacitidine in MDS is associated with distinct DNA methylation changes in HSPCs Open
Hypomethylating agents are frontline therapies for myelodysplastic neoplasms (MDS), yet clinical responses remain unpredictable. We conducted a phase 2 trial comparing injectable and oral azacitidine (AZA) administered over one or three we…
View article: Clinical Response to Azacitidine in Myelodysplastic Neoplasms is Associated with Distinct DNA Methylation Changes in Haematopoietic Stem and Progenitor cells<i>in vivo</i>
Clinical Response to Azacitidine in Myelodysplastic Neoplasms is Associated with Distinct DNA Methylation Changes in Haematopoietic Stem and Progenitor cells<i>in vivo</i> Open
Hypomethylating agents are used as frontline therapy for myelodysplastic neoplasms (MDS), but clinical response is unpredictable. To determine whether response was associated with in vivo dynamics of DNA hypomethylation, we conducted a pha…
View article: Genome-Wide CRISPR-Cas9 Screening Identifies a Synergy between Hypomethylating Agents and SUMOylation Blockade in MDS/AML
Genome-Wide CRISPR-Cas9 Screening Identifies a Synergy between Hypomethylating Agents and SUMOylation Blockade in MDS/AML Open
Hypomethylating agents (HMAs) are frontline therapies effective at altering the natural course of Myelodysplastic Neoplasms (MDS) and Acute Myeloid Leukemia (AML). However, acquired resistance and treatment failure are hallmarks of HMA the…
View article: Hierarchical Materials from High Information Content Macromolecular Building Blocks: Construction, Dynamic Interventions, and Prediction
Hierarchical Materials from High Information Content Macromolecular Building Blocks: Construction, Dynamic Interventions, and Prediction Open
Hierarchical materials that exhibit order over multiple length scales are ubiquitous in nature. Because hierarchy gives rise to unique properties and functions, many have sought inspiration from nature when designing and fabricating hierar…
View article: Amphiphilic Peptoid‐Directed Assembly of Oligoanilines into Highly Crystalline Conducting Nanotubes
Amphiphilic Peptoid‐Directed Assembly of Oligoanilines into Highly Crystalline Conducting Nanotubes Open
It is reported herein the synthesis of a novel amphiphilic diblock peptoid bearing a terminal conjugated oligoaniline and its self‐assembly into small‐diameter ( D ≈ 35 nm) crystalline nanotubes with high aspect ratios (>30). It is shown t…
View article: Peer Review #2 of "Taxonomic, functional and expression analysis of viral communities associated with marine sponges (v0.2)"
Peer Review #2 of "Taxonomic, functional and expression analysis of viral communities associated with marine sponges (v0.2)" Open
Viruses play an essential role in shaping the structure and function of ecological communities.Marine sponges have the capacity to filter large volumes of "virus-laden" seawater through their bodies and host dense communities of microbial …
View article: Peer Review #2 of "Taxonomic, functional and expression analysis of viral communities associated with marine sponges (v0.3)"
Peer Review #2 of "Taxonomic, functional and expression analysis of viral communities associated with marine sponges (v0.3)" Open
Viruses play an essential role in shaping the structure and function of ecological communities.Marine sponges have the capacity to filter large volumes of "virus-laden" seawater through their bodies and host dense communities of microbial …
View article: Peer Review #1 of "Taxonomic, functional and expression analysis of viral communities associated with marine sponges (v0.2)"
Peer Review #1 of "Taxonomic, functional and expression analysis of viral communities associated with marine sponges (v0.2)" Open
Viruses play an essential role in shaping the structure and function of ecological communities.Marine sponges have the capacity to filter large volumes of "virus-laden" seawater through their bodies and host dense communities of microbial …
View article: Peer Review #1 of "Taxonomic, functional and expression analysis of viral communities associated with marine sponges (v0.1)"
Peer Review #1 of "Taxonomic, functional and expression analysis of viral communities associated with marine sponges (v0.1)" Open
Viruses play an essential role in shaping the structure and function of ecological communities.Marine sponges have the capacity to filter large volumes of "virus-laden" seawater through their bodies and host dense communities of microbial …
View article: Peer Review #2 of "Taxonomic, functional and expression analysis of viral communities associated with marine sponges (v0.1)"
Peer Review #2 of "Taxonomic, functional and expression analysis of viral communities associated with marine sponges (v0.1)" Open
Viruses play an essential role in shaping the structure and function of ecological communities.Marine sponges have the capacity to filter large volumes of "virus-laden" seawater through their bodies and host dense communities of microbial …
View article: Taxonomic, functional and expression analysis of viral communities associated with marine sponges
Taxonomic, functional and expression analysis of viral communities associated with marine sponges Open
Viruses play an essential role in shaping the structure and function of ecological communities. Marine sponges have the capacity to filter large volumes of ‘virus-laden’ seawater through their bodies and host dense communities of microbial…
View article: Navigating Naturopathic Remedies in Oncology
Navigating Naturopathic Remedies in Oncology Open
The use of naturopathic and other alternative forms of cancer treatment are pervasive, and many patients may firmly believe in their effectiveness. This can present headwinds for physicians who have been trained to incorporate evidence-bas…
View article: Galactose-alpha-1,3-galactose syndrome
Galactose-alpha-1,3-galactose syndrome Open
The galactose-alpha-1,3-galactose (alpha-Gal) syndrome is a newly recognized and unique form of food allergy, characterized by delayed reactions to mammalian meats. This form of allergy occurs in individuals who become sensitized to alpha-…
View article: Macromolecular Engineering by Applying Concurrent Reactions with ATRP
Macromolecular Engineering by Applying Concurrent Reactions with ATRP Open
Modern polymeric material design often involves precise tailoring of molecular/supramolecular structures which is also called macromolecular engineering. The available tools for molecular structure tailoring are controlled/living polymeriz…
View article: CCDC 1964620: Experimental Crystal Structure Determination
CCDC 1964620: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1964621: Experimental Crystal Structure Determination
CCDC 1964621: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Cobaviruses – a new globally distributed phage group infecting <i>Rhodobacteraceae</i> in marine ecosystems
Cobaviruses – a new globally distributed phage group infecting <i>Rhodobacteraceae</i> in marine ecosystems Open
Bacteriophages are widely considered to influence bacterial communities, however most phages are still unknown or not studied well enough to understand their ecological roles. We have isolated two phages infecting Lentibacter sp. SH36, aff…
View article: Peer Review #3 of "Diversity, host-specificity and stability of sponge-associated fungal communities of co-occurring sponges (v0.2)"
Peer Review #3 of "Diversity, host-specificity and stability of sponge-associated fungal communities of co-occurring sponges (v0.2)" Open
Fungi play a critical role in a range of ecosystems, however their interactions and functions in marine hosts, and particular sponges, is poorly understood.Here we assess the fungal community composition of three co-occurring sponges (Cymb…
View article: Peer Review #3 of "Diversity, host-specificity and stability of sponge-associated fungal communities of co-occurring sponges (v0.1)"
Peer Review #3 of "Diversity, host-specificity and stability of sponge-associated fungal communities of co-occurring sponges (v0.1)" Open
Fungi play a critical role in a range of ecosystems, however their interactions and functions in marine hosts, and particular sponges, is poorly understood.Here we assess the fungal community composition of three co-occurring sponges (Cymb…
View article: Diversity, host-specificity and stability of sponge-associated fungal communities of co-occurring sponges
Diversity, host-specificity and stability of sponge-associated fungal communities of co-occurring sponges Open
Fungi play a critical role in a range of ecosystems; however, their interactions and functions in marine hosts, and particular sponges, is poorly understood. Here we assess the fungal community composition of three co-occurring sponges ( C…
View article: Sample Processing Impacts the Viability and Cultivability of the Sponge Microbiome
Sample Processing Impacts the Viability and Cultivability of the Sponge Microbiome Open
Sponges host complex microbial communities of recognized ecological and biotechnological importance. Extensive cultivation efforts have been made to isolate sponge bacteria, but most still elude cultivation. To identify the bottlenecks of …
View article: Characterization of light-dependent regulation of state transitions in gymnosperms
Characterization of light-dependent regulation of state transitions in gymnosperms Open
The goal of this study was to characterize the light-dependent regulation of state transitions in gymnosperms. Two species of conifer were examined: eastern white pine (Pinus strobus L.) and white spruce [Picea glauca (Moench) Voss], as we…