Travis W. Moore
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View article: Cell free RNA detection of pancreatic cancer in pre diagnostic high risk and symptomatic patients
Cell free RNA detection of pancreatic cancer in pre diagnostic high risk and symptomatic patients Open
View article: Multiomic profiling of hypoxic glioblastoma stem cells reveals expansion of subpopulations with distinct epigenetic and CNV profiles
Multiomic profiling of hypoxic glioblastoma stem cells reveals expansion of subpopulations with distinct epigenetic and CNV profiles Open
Glioblastoma is characterized by extensive intratumoral heterogeneity driven by dynamic mi-croenvironmental cues such as hypoxia. While transcriptional and epigenetic variability have been separately linked to hypoxia responses, the integr…
View article: A Scaled Proteomic Discovery Study for Prostate Cancer Diagnostic Markers Using ProteographTM and Trapped Ion Mobility Mass Spectrometry
A Scaled Proteomic Discovery Study for Prostate Cancer Diagnostic Markers Using ProteographTM and Trapped Ion Mobility Mass Spectrometry Open
There is a significant unmet need for clinical reflex tests that increase the specificity of prostate-specific antigen blood testing, the longstanding but imperfect tool for prostate cancer diagnosis. Towards this endpoint, we present the …
View article: Accessible high-throughput single-cell whole-genome sequencing with paired chromatin accessibility
Accessible high-throughput single-cell whole-genome sequencing with paired chromatin accessibility Open
Single-cell whole-genome sequencing (scWGS) enables the assessment of genome-level molecular differences between individual cells with particular relevance to genetically diverse systems like solid tumors. The application of scWGS was limi…
View article: Robust CNV detection using single-cell ATAC-seq
Robust CNV detection using single-cell ATAC-seq Open
Copy number variation (CNV) is a widely studied type of structural variation seen in the genomes of cancerous and other dysfunctional cells. CNVs can have direct and indirect effects on gene dosage, and are thought to drive cancer progress…