Thomas Abraham
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View article: Impact of fine particulate matter air pollution (PM2·5) on Nigerian children’s performance on tests of cognitive and neurobehavioral development at age seven years
Impact of fine particulate matter air pollution (PM2·5) on Nigerian children’s performance on tests of cognitive and neurobehavioral development at age seven years Open
Elevated personal PM2·5 exposures during middle childhood are associated with lower developmental assessment scores in Nigerian seven-year-old children. Household use of polluting cooking fuels contributes to these exposures.
View article: Assessment of Pain, Diet and Analgesic Use in Orthodontic Patients
Assessment of Pain, Diet and Analgesic Use in Orthodontic Patients Open
Background: Orthodontic treatment often causes varying levels of pain, particularly following appliance placement and adjustments. Objectives: To assess the intensity and progression of orthodontic pain, examine dietary modifications in re…
View article: Managing Differences in Global Learning: Perceptions and Practices of Teachers in Bukavu/DRCongo
Managing Differences in Global Learning: Perceptions and Practices of Teachers in Bukavu/DRCongo Open
This study explores teachers’ perceptions of global learning in the Democratic Republic of Congo (DRC) and how they manage differences in culturally and linguistically diverse classrooms. In an increasingly interconnected world, global lea…
View article: Porcine intestinal organoids cultured in an organ-on-a-chip microphysiological system
Porcine intestinal organoids cultured in an organ-on-a-chip microphysiological system Open
Preclinical studies are a vital component of pharmaceutical development and improvements in the predictive value of in vitro studies are essential. Organ-on-a-chip in vitro models are a recent advancement in the pursuit of improved reprodu…
View article: Effect of vermicompost and NPSB with urea fertilizer rates on finger millet yield and soil physico-chemical properties at Gobu Sayo district, Ethiopia
Effect of vermicompost and NPSB with urea fertilizer rates on finger millet yield and soil physico-chemical properties at Gobu Sayo district, Ethiopia Open
In Ethiopia’s highlands and middle lands, finger millet is a significant food and beverage crop; but, poor farming practices and ineffective fertilizer use have led to nutrient depletion and declining crop yields. In light of this, a study…
View article: Comparative study of soft tissue parameters reliability by digital and manual tracing method: A cephalometric study
Comparative study of soft tissue parameters reliability by digital and manual tracing method: A cephalometric study Open
Aim: To compare and evaluate soft tissue linear and angular measurements reliability between Digital and Manual Tracing method Objectives: The objective of the study is to conclude that digital and manual tracing method for soft tissue mea…
View article: Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial
Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial Open
UK Research and Innovation (Medical Research Council) and National Institute for Health Research (Grant ref: MC_PC_19056), and Wellcome Trust (Grant Ref: 222406/Z/20/Z).
View article: CCK Receptor Inhibition Reduces Pancreatic Tumor Fibrosis and Promotes Nanoparticle Delivery
CCK Receptor Inhibition Reduces Pancreatic Tumor Fibrosis and Promotes Nanoparticle Delivery Open
The poor prognosis for pancreatic ductal adenocarcinoma (PDAC) patients is due in part to the highly fibrotic nature of the tumors that impedes delivery of therapeutics, including nanoparticles (NPs). Our prior studies demonstrated that pr…
View article: Atrial Fibrillation In Patients With Stroke Attributed to Large- or Small-Vessel Disease
Atrial Fibrillation In Patients With Stroke Attributed to Large- or Small-Vessel Disease Open
Importance The STROKE AF study found that in patients with prior ischemic stroke attributed to large-artery atherosclerotic disease (LAD) or small-vessel occlusive disease (SVD), 12% developed AF over 1 year when monitored with an insertab…
View article: Modelling information usage and decision processes in new product introductions : an information-processing perspective.
Modelling information usage and decision processes in new product introductions : an information-processing perspective. Open
The objective of this study is to understand the problem solving process used in new product introductions, and other unstructured business problems. I hope this understanding will contribute to improved decision support systems. Based on …
View article: Unlocking the Science of Emotions through Pattern Recognition: Establishing Emotions as a Proper Field of Study
Unlocking the Science of Emotions through Pattern Recognition: Establishing Emotions as a Proper Field of Study Open
This study investigates the hypothesis that emotions are expressions of the combinatorial code language of internal representation for the mind. It suggests that emotions are a result of pattern recognition outputs of the nervous system, a…
View article: Integrated Effect of Vermicompost and Inorganic Fertilizer Rates on Yield and Yield Components of Finger Millet [Eleusine coracana (L.) Gaertn.] in Gobu-Sayo District
Integrated Effect of Vermicompost and Inorganic Fertilizer Rates on Yield and Yield Components of Finger Millet [Eleusine coracana (L.) Gaertn.] in Gobu-Sayo District Open
Finger millet is an important food and beverage crop in the highlands and mid lands of Ethiopia, however marginal cultivation and suboptimal fertilizer application have caused soil nutrient depletion and yield decline of the crop. With thi…
View article: Effect of Soil Compaction and Sowing Dates on Growth and Yield of Three Tef [Eragrostis tef (Zucc) Trotter] Varieties in Toke Kutaye District, Ethiopia
Effect of Soil Compaction and Sowing Dates on Growth and Yield of Three Tef [Eragrostis tef (Zucc) Trotter] Varieties in Toke Kutaye District, Ethiopia Open
Tef is a highly valued crop in Ethiopia as tef flour used to prepare Injera which is the most popular food of the country. However, its production and productivity are constrained by a number of problems, out of which soil compaction, inap…
View article: The role of tillage practices, nitrogen management by inorganic and organic manure and fertilizers and foliar applied of zinc on wheat (Triticum aestivum L.) crop performance and physico-chemical properties of soil under rainfed conditions
The role of tillage practices, nitrogen management by inorganic and organic manure and fertilizers and foliar applied of zinc on wheat (Triticum aestivum L.) crop performance and physico-chemical properties of soil under rainfed conditions Open
Field studies were conducted during rabi season of 2014-15 to 2015â16 to at Crop Research Farm, Block E ofSHUATS, Department of Agronomy, Naini Agricultural Institute, SHUATS, Prayagraj, to study effect oftillage practices, nitrogen and …
View article: An Early-stage Comparison of Functional Outcomes Following Robotic-assisted Versus Conventional Total Knee Arthroplasty: A Systematic Review and Meta-analysis
An Early-stage Comparison of Functional Outcomes Following Robotic-assisted Versus Conventional Total Knee Arthroplasty: A Systematic Review and Meta-analysis Open
Introduction: Conventional total knee arthroplasty (cTKA) is used to relieve pain and restore knee function and stability. Robotic-assisted TKA (rTKA) was introduced to improve the placement of surgical implants, decrease postoperative com…
View article: PIGN spatiotemporally regulates the spindle assembly checkpoint proteins in leukemia transformation and progression
PIGN spatiotemporally regulates the spindle assembly checkpoint proteins in leukemia transformation and progression Open
Phosphatidylinositol glycan anchor biosynthesis class N (PIGN) has been linked to the suppression of chromosomal instability. The spindle assembly checkpoint complex is responsible for proper chromosome segregation during mitosis to preven…
View article: One‐Year Landmark Analysis of the Effect of Beta‐Blocker Dose on Survival After Acute Myocardial Infarction
One‐Year Landmark Analysis of the Effect of Beta‐Blocker Dose on Survival After Acute Myocardial Infarction Open
Background Although beta‐blockers are recommended following myocardial infarction (MI), the benefits of long‐term treatment have not been established. The study's aim was to evaluate beta‐blocker efficacy by dose in 1‐year post‐MI survivor…
View article: Discovery of a Highly Conserved Peptide in the Iron Transporter Melanotransferrin that Traverses an Intact Blood Brain Barrier and Localizes in Neural Cells
Discovery of a Highly Conserved Peptide in the Iron Transporter Melanotransferrin that Traverses an Intact Blood Brain Barrier and Localizes in Neural Cells Open
The blood-brain barrier (BBB) hinders the distribution of therapeutics intended for treatment of diseases of the brain. Our previous studies demonstrated that that a soluble form of melanotransferrin (MTf; Uniprot P08582; also known as p97…
View article: Effect of Long-term Continuous Cardiac Monitoring vs Usual Care on Detection of Atrial Fibrillation in Patients With Stroke Attributed to Large- or Small-Vessel Disease
Effect of Long-term Continuous Cardiac Monitoring vs Usual Care on Detection of Atrial Fibrillation in Patients With Stroke Attributed to Large- or Small-Vessel Disease Open
ClinicalTrials.gov Identifier: NCT02700945.
View article: Corrigendum: A Nanomule Peptide Carrier Delivers siRNA Across the Intact Blood-Brain Barrier to Attenuate Ischemic Stroke
Corrigendum: A Nanomule Peptide Carrier Delivers siRNA Across the Intact Blood-Brain Barrier to Attenuate Ischemic Stroke Open
CORRECTION article Front. Mol. Biosci., 07 May 2021Sec. Molecular Diagnostics and Therapeutics https://doi.org/10.3389/fmolb.2021.687587
View article: A Nanomule Peptide Carrier Delivers siRNA Across the Intact Blood-Brain Barrier to Attenuate Ischemic Stroke
A Nanomule Peptide Carrier Delivers siRNA Across the Intact Blood-Brain Barrier to Attenuate Ischemic Stroke Open
The blood-brain barrier (BBB) hinders the distribution of therapeutics intended for treatment of neuroinflammation (NI) of the central nervous system. A twelve-amino acid peptide that transcytoses the BBB, termed MTfp, was chemically conju…
View article: Aptamer-Targeted Calcium Phosphosilicate Nanoparticles for Effective Imaging of Pancreatic and Prostate Cancer
Aptamer-Targeted Calcium Phosphosilicate Nanoparticles for Effective Imaging of Pancreatic and Prostate Cancer Open
Through specific interactions with CCK-B receptors, tumor-targeted nanoparticles containing either ICG or rhodamine WT were well distributed throughout the matrix of both pancreatic and prostate tumors. Tumor-targeted NJs carrying various …
View article: An Empirical Examination of the Use of IS-enabled Sustainability Initiatives across the Integrated Sustainability Framework
An Empirical Examination of the Use of IS-enabled Sustainability Initiatives across the Integrated Sustainability Framework Open
Background: Using the Resource Based View (RBV) and the Integrated Sustainability Framework (ISF) as theoretical foundation, this study proposes and empirically examines hypotheses on how different types of IS-enabled sustainability initia…
View article: PIGN Spatiotemporally Regulates the Spindle Assembly Checkpoint Proteins in Myelodysplastic Syndromes
PIGN Spatiotemporally Regulates the Spindle Assembly Checkpoint Proteins in Myelodysplastic Syndromes Open
Phosphatidylinositol glycan anchor biosynthesis class N (PIGN) has been previously linked to the suppression of chromosomal instability. The spindle assembly checkpoint complex is responsible for proper chromosome segregation during mitosi…