Tsun Ming Lau
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View article: Outcomes of pediatric patients with suspected allergies to COVID-19 vaccines
Outcomes of pediatric patients with suspected allergies to COVID-19 vaccines Open
Children with a history of urticaria or angioedema related or unrelated to prior COVID-19 vaccination were at higher risk of a COVID-19-related AEFI on revaccination, although most were able to complete the vaccination series under the man…
View article: Outcomes of X-Linked Agammaglobulinaemia Patients
Outcomes of X-Linked Agammaglobulinaemia Patients Open
View article: Superior antibody and membrane protein-specific T-cell responses to CoronaVac by intradermal versus intramuscular routes in adolescents
Superior antibody and membrane protein-specific T-cell responses to CoronaVac by intradermal versus intramuscular routes in adolescents Open
Background Optimising the immunogenicity of COVID-19 vaccines to improve their protection against disease is necessary. Fractional dosing by intradermal (ID) administration has been shown to be equally immunogenic as intramuscular (IM) adm…
View article: Superior antibody and membrane protein-specific T cell responses to CoronaVac by intradermal versus intramuscular routes in adolescents
Superior antibody and membrane protein-specific T cell responses to CoronaVac by intradermal versus intramuscular routes in adolescents Open
Strategies to improve the immunogenicity of COVID-19 vaccines are necessary to optimise their protection against disease. Fractional dosing by intradermal administration (ID) has been shown to be equally immunogenic as intramuscular (IM) f…
View article: Chronic alcohol metabolism results in <scp>DNA</scp> repair infidelity and cell cycle‐induced senescence in neurons
Chronic alcohol metabolism results in <span>DNA</span> repair infidelity and cell cycle‐induced senescence in neurons Open
Chronic binge‐like drinking is a risk factor for age‐related dementia, however, the lasting and irreversible effect of alcohol on the brain remains elusive. Transcriptomic changes in brain cortices revealed pro‐ageing hallmarks upon chroni…
View article: Low‐Density Lipoprotein Receptor‐Related Protein 6 Cell Surface Availability Regulates Fuel Metabolism in Astrocytes
Low‐Density Lipoprotein Receptor‐Related Protein 6 Cell Surface Availability Regulates Fuel Metabolism in Astrocytes Open
Early changes in astrocyte energy metabolism are associated with late‐onset Alzheimer's disease (LOAD), but the underlying mechanism remains elusive. A previous study suggested an association between a synonymous SNP (rs1012672, C→T) in LR…