T. Sharma
YOU?
Author Swipe
View article: Miliary tuberculosis in a captive smooth-coated otter (Lutrogale perspicillata) in South Asia (India)
Miliary tuberculosis in a captive smooth-coated otter (Lutrogale perspicillata) in South Asia (India) Open
Background Tuberculosis is rarely observed in smooth-coated otter. This report describes a case of tuberculosis in an Asian smooth-coated otter ( Lutrogale perspicillata ). A ten-year-old male otter that had been raised in a zoological gar…
View article: <i>PPARγ</i> and <i>AKt</i> gene modulation following pregabalin and duloxetine combination for painful diabetic polyneuropathy
<i>PPARγ</i> and <i>AKt</i> gene modulation following pregabalin and duloxetine combination for painful diabetic polyneuropathy Open
Aim: Diabetic peripheral neuropathy (DPN) induces chronic neuropathic pain in diabetic patients. Current treatments like pregabalin and duloxetine offer limited efficacy. This study evaluates combining pregabalin and duloxetine vers…
View article: Impact of Poly(ADP-Ribose) Polymerase (PARP) and Immune Checkpoint Inhibitor Combinations on the Viability of Triple-Negative Breast Cancer Cells
Impact of Poly(ADP-Ribose) Polymerase (PARP) and Immune Checkpoint Inhibitor Combinations on the Viability of Triple-Negative Breast Cancer Cells Open
Background: Breast cancer is one of the most common cancer types and the second most frequent one among women in the United States [...]
View article: Modulation of microRNA-133B in Post Mastectomy Pain Syndrome Following Yoga Intervention
Modulation of microRNA-133B in Post Mastectomy Pain Syndrome Following Yoga Intervention Open
Objectives: This study aimed to compare the efficacy of yoga combined with an integrated multimodal approach on the incidence and severity of post-mastectomy pain syndrome (PMPS) and the role of miR-133B expressions in patients undergoing …
View article: The Variations Between Early and Late-Onset Alzheimer's Disease in Terms of Mini Mental State Examination Scores and Biochemical Profile
The Variations Between Early and Late-Onset Alzheimer's Disease in Terms of Mini Mental State Examination Scores and Biochemical Profile Open
the aim of this present study is about interrelation between biochemical markers and cognitive scores in patients with EOAD and LOAD in Himachal Pradesh state in India, in this study 31 Alzheimer patients were enrolled from various regions…
View article: Gut microbiota: a non-target victim of pesticide-induced toxicity
Gut microbiota: a non-target victim of pesticide-induced toxicity Open
The human gut microbiota can be potentially disrupted due to exposure of various environmental contaminants, including pesticides. These contaminants enter into non-target species in multiple ways and cause potential health risks. The gut …
View article: Risk Factors of Incident Kidney Stones in Indian Adults: A Hospital-Based Cross-Sectional Study
Risk Factors of Incident Kidney Stones in Indian Adults: A Hospital-Based Cross-Sectional Study Open
View article: Effect of Supplementation of Tinospora cordifolia (at Graded Levels) and Ascorbic Acid on Nutrient Metabolizability and Feed Passage Rate of Broiler Chickens
Effect of Supplementation of Tinospora cordifolia (at Graded Levels) and Ascorbic Acid on Nutrient Metabolizability and Feed Passage Rate of Broiler Chickens Open
A study was conducted September to October, 2016 to investigate the effect of Tinospora cordifolia (at graded levels) or ascorbic acid alone and in combinations on nutrient metabolizability and feed passage rate using 360 one day old broil…
View article: Role of mRNA expression of interleukin-6 and interleukin-10 in idiopathic preterm birth
Role of mRNA expression of interleukin-6 and interleukin-10 in idiopathic preterm birth Open
Background: India is one of the nation’s leading in number of preterm births (PTB), as reported by WHO. Despite extensive research the exact cause of PTB remains elusive. The present study was designed to study the effect of inflammatory g…
View article: Role of the AMPK signalling pathway in the aetiopathogenesis of ocular diseases
Role of the AMPK signalling pathway in the aetiopathogenesis of ocular diseases Open
Background AMP-activated protein kinase (AMPK) plays a precise role as a master regulator of cellular energy homeostasis. AMPK is activated in response to the signalling cues that exhaust cellular ATP levels such as hypoxia, ischaemia, glu…
View article: Modulation of the Extracellular Signal-Regulated Protein Kinase and Tissue Inhibitors of Matrix Metalloproteases-1 Gene in Chronic Neuropathic Pain
Modulation of the Extracellular Signal-Regulated Protein Kinase and Tissue Inhibitors of Matrix Metalloproteases-1 Gene in Chronic Neuropathic Pain Open
Objectives: The aim of this study is to study the modulation of extracellular signal-regulated protein kinase (ERK) and tissue inhibitors of matrix metalloproteases 1 (TIMP 1) gene in patients with neuropathic pain (NP). Materials and Meth…
View article: 745 Risk Factors of Incident Renal Stones in Indian Population: A Hospital-Based Case-Control Study
745 Risk Factors of Incident Renal Stones in Indian Population: A Hospital-Based Case-Control Study Open
Introduction Nephrolithiasis is pathological calcification in the excretory passages of the body and is prevalent among 7.6% of Indians. We aimed to study the various risk factors associated with renal stones from India. Method It was a ho…
View article: Effect of Feeding Moringa oleifera Leaf Meal with Multienzyme on Performance, Carcass Characteristics and Economics of Production of Broiler Chicks
Effect of Feeding Moringa oleifera Leaf Meal with Multienzyme on Performance, Carcass Characteristics and Economics of Production of Broiler Chicks Open
Background: Moringa leaves have wide range of medicinal value including antimicrobial property. Therefore, it could be an alternative of antibiotic growth promoters in poultry but the presence of phytate and other anti-nutrients can reduce…
View article: Adipose Tissue Levels of DDT as Risk Factor for Obesity and Type 2 Diabetes Mellitus
Adipose Tissue Levels of DDT as Risk Factor for Obesity and Type 2 Diabetes Mellitus Open
Background: Exposure to dichlorodiphenyltrichloroethane (DDT), a potent lipophilic organochlorine pesticide, has long been linked as a risk factor for type 2 diabetes mellitus (T2DM). However, its presence in the adipose tissues of the T2D…
View article: Level of Organochlorine Pesticide in Prediabetic and Newly Diagnosed Diabetes Mellitus Patients with Varying Degree of Glucose Intolerance and Insulin Resistance among North Indian Population
Level of Organochlorine Pesticide in Prediabetic and Newly Diagnosed Diabetes Mellitus Patients with Varying Degree of Glucose Intolerance and Insulin Resistance among North Indian Population Open
Background: Organochlorine pesticides (OCPs) exposure may induce an endocrine disruption which may lead to the risk of developing diabetes through alteration and disturbance of glucose metabolism, insulin resistance, and destruction of β-c…
View article: Effect of Feeding Moringa oleifera Leaf Meal as Feed Additive on the Performance and Carcass Characteristics of Broiler Chicks
Effect of Feeding Moringa oleifera Leaf Meal as Feed Additive on the Performance and Carcass Characteristics of Broiler Chicks Open
A study was carried out to evaluate the effect of Moringa oleifera leaf meal (MOLM) as feed additive on the growth performance and carcass characteristics of broiler chicks.A total of 150 one day-old broiler chicks (Vencobb-400) were rando…
View article: Effect of supplementation of Tinospora cordifolia and ascorbic acid either alone or in combinations on leucogram of broiler chickens
Effect of supplementation of Tinospora cordifolia and ascorbic acid either alone or in combinations on leucogram of broiler chickens Open
View article: Effect of incorporation of dried distillers grains with solubles (ddgs) in total mixed ration of magra lambs on blood parameters
Effect of incorporation of dried distillers grains with solubles (ddgs) in total mixed ration of magra lambs on blood parameters Open
The present experiment was conducted at ARC-CSWRI for thirteen weeks on Magra lambs of 3-4 months of age to observe the effect of incorporation of dried distillers grains with solubles (DDGS) in total mixed ration of magra lambs on blood p…
View article: Effect of Supplementation of Herbal Products as Feed Additive on Rumen Metabolites in Marwari Goats
Effect of Supplementation of Herbal Products as Feed Additive on Rumen Metabolites in Marwari Goats Open
The present study was conducted to investigate the effect of herbal products supplementation on rumen environment in Marwari goats. Marwari goats of 18-24 months of age were randomly divided into five groups (four in each) i.e. T1 (complet…
View article: Effect of supplementation of Tinospora cordifolia (Thunb.) Miers and ascorbic acid either alone or in combinations on serum protein profile and AG ratio of broiler chickens
Effect of supplementation of Tinospora cordifolia (Thunb.) Miers and ascorbic acid either alone or in combinations on serum protein profile and AG ratio of broiler chickens Open
A 42 day feeding trial was carried out to investigate the effect of Tinospora cordifolia (at graded levels) or ascorbic acid alone and in combinations on Leucogram and H/L ratio using 360 one-day-old broiler chicks in 5×2 factorial experim…
View article: A Case Control Study of Gene Environment Interaction in Pre-Eclampsia with Special Reference to Organochlorine Pesticides
A Case Control Study of Gene Environment Interaction in Pre-Eclampsia with Special Reference to Organochlorine Pesticides Open
Objectives: To study and compare the frequency of GSTM1 & T1 gene polymorphism in cases (Pre-eclampsia) and controls (normal pregnancy), to estimate and compare serum levels of Glutathione-S-Transferase enzyme in cases and controls, to qua…
View article: Effect of supplementation of geloi (<i>Tinospora Cordifolia</i>) stem powder and ascorbic acid on economics of broiler production in arid zone of Rajasthan
Effect of supplementation of geloi (<i>Tinospora Cordifolia</i>) stem powder and ascorbic acid on economics of broiler production in arid zone of Rajasthan Open
View article: Organochlorine pesticide exposure as a risk factor for breast cancer in young Indian women: A case–control study
Organochlorine pesticide exposure as a risk factor for breast cancer in young Indian women: A case–control study Open
Background: Incidence rates of breast cancer are showing an increasing trend in young women (≤40 years) in India. Risk for breast cancer in this age group can be attributed only partially to various known risk factors. Environmental exposu…
View article: High Resolution Based Quantitative Determination of Methylation Status of CDH1 and VIM Gene in Epithelial Ovarian Cancer
High Resolution Based Quantitative Determination of Methylation Status of CDH1 and VIM Gene in Epithelial Ovarian Cancer Open
In short HRM based DNA methylation can serve as a robust and sensitive diagnostic method for promoter methylation detection and as a biomarker for early epithelial ovarian cancer detection.
View article: Polymorphism of xenobiotic metabolizing gene and susceptibility of epithelial ovarian cancer with reference to organochlorine pesticides exposure
Polymorphism of xenobiotic metabolizing gene and susceptibility of epithelial ovarian cancer with reference to organochlorine pesticides exposure Open
The transformation of ovarian surface epithelial cells, stromal cells, sex cord, or germ cells initiates ovarian malignancy. Epithelial ovarian cancer (EOC) is clinically silent with vague, non-specific symptomatology and is generally diag…
View article: Effect of Feeding of Hydroponic Maize Fodder on Milk Production in Rathi Cows
Effect of Feeding of Hydroponic Maize Fodder on Milk Production in Rathi Cows Open
Sixteen lactating Rathi cows (BW 340–360 kg with average milk yield of ∼5–6 kg/d) were distributed in four equal groups in order to study the effect of feeding of hydroponic maize fodder on milk production during a 120 d feeding trial. The…
View article: Organochlorine Pesticides Exposure as a Risk Factor for Breast Cancer in Young Women: A Case Control Study
Organochlorine Pesticides Exposure as a Risk Factor for Breast Cancer in Young Women: A Case Control Study Open
Background: Young women (< 40 years) constitutes about 10%–25% of total breast cancer cases in south-Asian women and an increase in incidence rates have been noted in the recent past. It is higher compared with their western counterparts, …
View article: Delineating Potential Transcriptomic Association with Organochlorine Pesticides in the Etiology of Epithelial Ovarian Cancer
Delineating Potential Transcriptomic Association with Organochlorine Pesticides in the Etiology of Epithelial Ovarian Cancer Open
This study provides the first evidence showing that differentially expressed genes and dysregulation of signaling pathways might be associated with significant level of OCPs exposure in ovary tissue of epithelial ovarian cancer patients. M…
View article: Effect of phytase supplementation in maize–soybean based feed on comparative economy for broilers production
Effect of phytase supplementation in maize–soybean based feed on comparative economy for broilers production Open
A 42-days experiment with 150 one-day-old broiler chicks (Vencobb) was conducted in order to determine the effect of supplementation of phytase enzyme on comparative economics of rearing of broilers. Broilers were reared on phosphorus defi…
View article: Effect of phytase supplementation in maize–soybean based feed on tibia bone characteristic of broiler chickens
Effect of phytase supplementation in maize–soybean based feed on tibia bone characteristic of broiler chickens Open
An experiment of 42 days with 150 one day-old broiler (Vencobb) chicks was conducted to determine the effect of supplementation of different levels of phytase enzyme on tibia characteristics of broilers fed on phosphorus deficient maize-so…