Ty J. Gluckman
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View article: PATIENT JOURNEY AND HEALTHCARE PROFESSIONALS’ PERSPECTIVES OF INFLAMMATION IN ATHEROSCLEROTIC CARDIOVASCULAR DISEASE
PATIENT JOURNEY AND HEALTHCARE PROFESSIONALS’ PERSPECTIVES OF INFLAMMATION IN ATHEROSCLEROTIC CARDIOVASCULAR DISEASE Open
View article: Temporal Shift in Prevalence of Heart Failure Diagnoses and Comorbidities Within 2 US Integrated Health Systems
Temporal Shift in Prevalence of Heart Failure Diagnoses and Comorbidities Within 2 US Integrated Health Systems Open
The study highlighted a significant shift in HF diagnosis codes, with hypertensive heart disease with HF with and without CKD now predominant. The findings highlight the need for standardized coding practices across health systems for qual…
View article: GLP-1 Receptor Agonists vs Alternatives for Alcohol Use Disorder: A Multi-Target Trial Emulation
GLP-1 Receptor Agonists vs Alternatives for Alcohol Use Disorder: A Multi-Target Trial Emulation Open
Background Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) have shown promise for alcohol use disorder (AUD). Objective To evaluate the association between use of newer GLP-1 RAs (semaglutide, tirzepatide) and alcohol-related hospita…
View article: Perceptions of high-sensitivity C-reactive protein testing (hsCRP) in atherosclerotic cardiovascular disease: a US survey on cardiologists and nephrologists
Perceptions of high-sensitivity C-reactive protein testing (hsCRP) in atherosclerotic cardiovascular disease: a US survey on cardiologists and nephrologists Open
In this limited study sample, perceived limitations of hsCRP testing included insufficient evidence of improved cardiovascular outcomes in patients with ASCVD.
View article: Health Disparity Clusters of Off Label Prescriptions for Glucagon-Like Peptide 1 Receptor Agonists
Health Disparity Clusters of Off Label Prescriptions for Glucagon-Like Peptide 1 Receptor Agonists Open
View article: High-sensitivity C-reactive Protein in Atherosclerotic Cardiovascular Disease: To Measure or Not to Measure?
High-sensitivity C-reactive Protein in Atherosclerotic Cardiovascular Disease: To Measure or Not to Measure? Open
Inflammation and dyslipidemia are central to the pathogenesis of atherosclerotic cardiovascular disease (ASCVD). While lipid-lowering therapies are the cornerstone of ASCVD prevention and treatment, there are other emerging targets, includ…
View article: Patterns of Prophylactic Anticoagulation Among Patients Hospitalized for COVID‐19: An Analysis of the American Heart Association COVID‐19 Cardiovascular Disease Registry
Patterns of Prophylactic Anticoagulation Among Patients Hospitalized for COVID‐19: An Analysis of the American Heart Association COVID‐19 Cardiovascular Disease Registry Open
Background Limited knowledge exists about prophylactic anticoagulation patterns in patients hospitalized for COVID‐19. Methods and Results We conducted a retrospective cohort study using American Heart Association COVID‐19 Cardiovascular D…
View article: Identification and management of cardiopulmonary risk in patients with chronic obstructive pulmonary disease: a multidisciplinary consensus and modified Delphi study
Identification and management of cardiopulmonary risk in patients with chronic obstructive pulmonary disease: a multidisciplinary consensus and modified Delphi study Open
Aims Cardiovascular disease is a common comorbidity in chronic obstructive pulmonary disease. Yet, cardiovascular disease and risk are underdiagnosed in chronic obstructive pulmonary disease and are often undertreated, increasing the risk …
View article: Prevalence and clinical characteristics of patients with hsCRP testing and test-confirmed systemic inflammation among individuals with atherosclerotic cardiovascular disease with or without chronic kidney disease in the United States (PLUTUS)
Prevalence and clinical characteristics of patients with hsCRP testing and test-confirmed systemic inflammation among individuals with atherosclerotic cardiovascular disease with or without chronic kidney disease in the United States (PLUTUS) Open
View article: Discontinuation and Reinitiation of Dual-Labeled GLP-1 Receptor Agonists Among US Adults With Overweight or Obesity
Discontinuation and Reinitiation of Dual-Labeled GLP-1 Receptor Agonists Among US Adults With Overweight or Obesity Open
Importance Adherence to glucagon-like peptide-1 receptor agonists (GLP-1 RAs) is important for their effectiveness. Discontinuation and reinitiation patterns are not well understood. Objective To describe rates of and factors associated wi…
View article: Relationship Between Left Ventricular Ejection Fraction and ICD‐10 Codes Among Patients Hospitalized With Heart Failure
Relationship Between Left Ventricular Ejection Fraction and ICD‐10 Codes Among Patients Hospitalized With Heart Failure Open
Introduction While left ventricular ejection fraction (LVEF) represents an important means by which to classify patients with heart failure (HF), relatively little is known about the distribution of LVEFs among patients hospitalized for HF…
View article: Emerging Educational and Networking Platforms in Interventional Cardiology: Expanding Beyond Traditional Social Media
Emerging Educational and Networking Platforms in Interventional Cardiology: Expanding Beyond Traditional Social Media Open
With ubiquitous use of smartphones and other Internet‐enabled devices, clinicians have access to a plethora of multimedia platforms that enable them to network, share educational content, and learn. Several platforms also enable resources …
View article: Discontinuation and Reinitiation of GLP-1 Receptor Agonists Among US Adults with Overweight or Obesity
Discontinuation and Reinitiation of GLP-1 Receptor Agonists Among US Adults with Overweight or Obesity Open
Importance Adherence to GLP-1 RA is important for efficacy. Discontinuation and reinitiation patterns for patients with and without type 2 diabetes (T2D) are not well-understood. Objective To describe rates and factors associated with disc…
View article: Semaglutide vs Tirzepatide for Weight Loss in Adults With Overweight or Obesity
Semaglutide vs Tirzepatide for Weight Loss in Adults With Overweight or Obesity Open
Importance Although tirzepatide and semaglutide were shown to reduce weight in randomized clinical trials, data from head-to-head comparisons in populations with overweight or obesity are not yet available. Objective To compare on-treatmen…
View article: Optimizing Care Delivery in Patients with Chronic Kidney Disease in the United States: Proceedings of a Multidisciplinary Roundtable Discussion and Literature Review
Optimizing Care Delivery in Patients with Chronic Kidney Disease in the United States: Proceedings of a Multidisciplinary Roundtable Discussion and Literature Review Open
Background: Approximately 37 million individuals in the United States (US) have chronic kidney disease (CKD). Patients with CKD have a substantial morbidity and mortality, which contributes to a huge economic burden to the healthcare syste…
View article: Comparative Effectiveness of Semaglutide and Tirzepatide for Weight Loss in Adults with Overweight and Obesity in the US: A Real-World Evidence Study
Comparative Effectiveness of Semaglutide and Tirzepatide for Weight Loss in Adults with Overweight and Obesity in the US: A Real-World Evidence Study Open
Background Both tirzepatide and semaglutide have been shown to reduce weight for patients with overweight or obesity in randomized controlled trials (RCTs). While tirzepatide appears to provide greater weight loss than semaglutide in this …
View article: First-Time Prescribing of GLP-1 Receptor Agonists from 2018-2023: A Descriptive Analysis
First-Time Prescribing of GLP-1 Receptor Agonists from 2018-2023: A Descriptive Analysis Open
Aims Limited recent data exist on prescribing patterns and patient characteristics for glucagon-like peptide 1 receptor agonists (GLP-1 RAs), an important drug class for patients with type 2 diabetes mellitus (T2D) and/or overweight or obe…
View article: Retrospective comparison of traditional and artificial intelligence-based heart failure phenotyping in a US health system to enable real-world evidence
Retrospective comparison of traditional and artificial intelligence-based heart failure phenotyping in a US health system to enable real-world evidence Open
Objective Quantitatively evaluate the quality of data underlying real-world evidence (RWE) in heart failure (HF). Design Retrospective comparison of accuracy in identifying patients with HF and phenotypic information was made using traditi…
View article: Characterization of Individuals With Apparent Resistant Hypertension Using Contemporary Guidelines: Insights From CV-QUIC
Characterization of Individuals With Apparent Resistant Hypertension Using Contemporary Guidelines: Insights From CV-QUIC Open
BACKGROUND: Apparent resistant hypertension (aRH) carries excess cardiovascular risk beyond nonresistant forms of hypertension; however, our understanding of this at-risk population, as defined by current US practice guidelines, is limited…
View article: Advance Care Planning and End-of-Life Education in Heart Failure: Insights From the NCDR PINNACLE Registry
Advance Care Planning and End-of-Life Education in Heart Failure: Insights From the NCDR PINNACLE Registry Open
View article: Sociodemographic determinants of oral anticoagulant prescription in patients with atrial fibrillations: findings from the PINNACLE registry using machine learning
Sociodemographic determinants of oral anticoagulant prescription in patients with atrial fibrillations: findings from the PINNACLE registry using machine learning Open
In a contemporary, national cohort of patients with AF underuse of OAC remains high, with notable geographic variation. Our results demonstrated the role of several important demographic and socioeconomic factors in underutilization of OAC…
View article: If the Fates Allow: The Zero-Sum Game of ISCHEMIA-EXTEND
If the Fates Allow: The Zero-Sum Game of ISCHEMIA-EXTEND Open
ccording to the ancient Greeks, the lives of the gods and mortals were immutably determined by 3 Fates: sisters Clotho, who spins the thread of life; Lachesis, who assigns each their destiny; and Atropos, whose scissors snip the thread of …
View article: Potential Impact of 2017 American College of Cardiology/American Heart Association Hypertension Guideline on Contemporary Practice: A Cross‐Sectional Analysis From NCDR PINNACLE Registry
Potential Impact of 2017 American College of Cardiology/American Heart Association Hypertension Guideline on Contemporary Practice: A Cross‐Sectional Analysis From NCDR PINNACLE Registry Open
Background Clinical implications of change in the 2017 American College of Cardiology (ACC)/American Heart Association (AHA) guideline on the diagnosis and management of hypertension, compared with recommendations by 2014 expert panel and …
View article: Clinical Trial Participation and COVID-19: a Descriptive Analysis from the American Heart Association’s Get With The Guidelines Registry
Clinical Trial Participation and COVID-19: a Descriptive Analysis from the American Heart Association’s Get With The Guidelines Registry Open
View article: Fulminant Myocarditis Following SARS-CoV-2 Infection
Fulminant Myocarditis Following SARS-CoV-2 Infection Open
View article: Fulminant Myocarditis Following SARS-CoV-2 Infection
Fulminant Myocarditis Following SARS-CoV-2 Infection Open
View article: 2022 ACC Expert Consensus Decision Pathway on Cardiovascular Sequelae of COVID-19 in Adults: Myocarditis and Other Myocardial Involvement, Post-Acute Sequelae of SARS-CoV-2 Infection, and Return to Play
2022 ACC Expert Consensus Decision Pathway on Cardiovascular Sequelae of COVID-19 in Adults: Myocarditis and Other Myocardial Involvement, Post-Acute Sequelae of SARS-CoV-2 Infection, and Return to Play Open
View article: Temporal trends and predictors of surgical ablation for atrial fibrillation across a multistate healthcare system
Temporal trends and predictors of surgical ablation for atrial fibrillation across a multistate healthcare system Open
Wide variability in rates of SA for AF exist, underscoring the need for greater preoperative collaboration between cardiologists, electrophysiologists, and cardiac surgeons.
View article: Repeated cross-sectional analysis of hydroxychloroquine deimplementation in the AHA COVID-19 CVD Registry
Repeated cross-sectional analysis of hydroxychloroquine deimplementation in the AHA COVID-19 CVD Registry Open
View article: Transradial Access for High-Risk Percutaneous Coronary Intervention: Implications of the Risk-Treatment Paradox
Transradial Access for High-Risk Percutaneous Coronary Intervention: Implications of the Risk-Treatment Paradox Open
Background: Transradial percutaneous coronary intervention (PCI; TRI) reduces adverse outcomes when compared with transfemoral PCI (TFI). However, TRI is also used less in high-risk patients. It remains unknown how baseline patient risk in…