Tyler Engel
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View article: The financial value of improving patient access to COVID-19 antiviral therapy in Medicare Part D: A simulation study
The financial value of improving patient access to COVID-19 antiviral therapy in Medicare Part D: A simulation study Open
Coverage of nirmatrelvir-ritonavir, on any tier, is cost-saving for the Medicare program overall. Preferred coverage with lower patient cost-sharing results in additional savings and improved patient outcomes from lower hospitalizations an…
View article: Prevalence and Economic Burden of Epilepsy in the Institutionalized Medicare Fee-for-Service Population.
Prevalence and Economic Burden of Epilepsy in the Institutionalized Medicare Fee-for-Service Population. Open
The high cost and inpatient resource utilization, as well as the projected growth of the institutionalized Medicare population with epilepsy highlight the need for further investigation of care management opportunities to reduce the cost b…
View article: The cost impact to Medicare of shifting treatment of worsening heart failure from inpatient to outpatient management settings
The cost impact to Medicare of shifting treatment of worsening heart failure from inpatient to outpatient management settings Open
Treatment options that can shift costly hospital admissions for worsening HF treatment to less expensive OP settings potentially lead to significant cost savings to Medicare. Pursuit of OP therapy options for treating worsening HF might be…
View article: Simulating Drug-Induced Arrhythmia Sensitivity using an Expression-Based Theoretical Model of Human IPSC-Derived Cardiomyocytes
Simulating Drug-Induced Arrhythmia Sensitivity using an Expression-Based Theoretical Model of Human IPSC-Derived Cardiomyocytes Open
View article: Computational Model for Simulating Drug-Induced Arrhythmia Sensitivity of Human iPSC-derived Cardiomyocytes
Computational Model for Simulating Drug-Induced Arrhythmia Sensitivity of Human iPSC-derived Cardiomyocytes Open
A mathematical model describing the electrophysiology and ion handling of cardiomyocytes is a complement to experimental analysis predicting drug-induced proarrhythmic potential in humans as proposed by Comprehensive in vitro Proarrhythmia…
View article: The Clinical and Economic Burden of Hyperkalemia on Medicare and Commercial Payers.
The Clinical and Economic Burden of Hyperkalemia on Medicare and Commercial Payers. Open
Hyperkalemia is associated with substantial clinical and economic burden among US commercially insured and Medicare populations.
View article: Computational modeling for cardiac safety pharmacology analysis: Contribution of fibroblasts
Computational modeling for cardiac safety pharmacology analysis: Contribution of fibroblasts Open
View article: Longitudinal Commercial Claims-Based Cost Analysis of Diabetic Retinopathy Screening Patterns.
Longitudinal Commercial Claims-Based Cost Analysis of Diabetic Retinopathy Screening Patterns. Open
Based on our analysis, the annual retinopathy screening rate for patients with diabetes has remained low since 2001, and has been well below the guideline-recommended screening levels. For patients with type 2 diabetes, the mean increase i…