Tze Kin Lau
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View article: A comparative analysis of deep learning-based quantitative hemorrhagic CT parameters versus traditional semi-quantitative CT scores for predicting delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage: a multicenter cohort study
A comparative analysis of deep learning-based quantitative hemorrhagic CT parameters versus traditional semi-quantitative CT scores for predicting delayed cerebral ischemia in aneurysmal subarachnoid hemorrhage: a multicenter cohort study Open
Background: Delayed cerebral ischemia (DCI) is the leading cause of poor outcomes after aneurysmal subarachnoid hemorrhage (aSAH). Hemorrhage extent assessment on pre-treatment CT is critical for DCI prediction, but traditional semi-quanti…
View article: Operational Challenges During the Rapid Intensification of Typhoon Wipha’s Near Hong Kong
Operational Challenges During the Rapid Intensification of Typhoon Wipha’s Near Hong Kong Open
Tropical cyclone Wipha brought destructive winds to Hong Kong in July 2025, resulting in many injuries and substantial property damage. Wipha posed considerable challenges for warning services because of (1) the high sensitivity of local w…
View article: Meteorological indices for potential occurrence of waterspout/tornado in Hong Kong
Meteorological indices for potential occurrence of waterspout/tornado in Hong Kong Open
Assessment of the potential occurrence of waterspouts and tornadoes in Hong Kong would be crucial in the timely alerting of these hazardous systems. This system provides for the first time a study of the meteorological parameters that may …
View article: Efficacy of the Web-Based Gamified Infection Control Training System on Practices for Health Care Workers in Residential Care Homes: Clustered Randomized Controlled Trial (Preprint)
Efficacy of the Web-Based Gamified Infection Control Training System on Practices for Health Care Workers in Residential Care Homes: Clustered Randomized Controlled Trial (Preprint) Open
BACKGROUND Staff working in residential care homes (RCHs) have played a significant role in preventing the spread of infection among residents, visitors, and staff. Providing continuous professional training to the staff is essential. Cur…
View article: Geodetic Monitoring at Axial Seamount Since Its 2015 Eruption Reveals a Waning Magma Supply and Tightly Linked Rates of Deformation and Seismicity
Geodetic Monitoring at Axial Seamount Since Its 2015 Eruption Reveals a Waning Magma Supply and Tightly Linked Rates of Deformation and Seismicity Open
Axial Seamount is a basaltic hot spot volcano with a summit caldera at a depth of ∼1,500 m below sea level, superimposed on the Juan de Fuca spreading ridge, giving it a robust and continuous magma supply. Axial erupted in 1998, 2011, and …
View article: A Fetus with Congenital Microcephaly, Microphthalmia and Cataract Was Detected with Biallelic Variants in the OCLN Gene: A Case Report
A Fetus with Congenital Microcephaly, Microphthalmia and Cataract Was Detected with Biallelic Variants in the OCLN Gene: A Case Report Open
Microcephaly and microphthalmia are both rare congenital abnormalities, while concurrently, these two are even rarer. The underlying etiology would be complex interplaying between heterogeneous genetic background and the environmental path…
View article: Clinical Implementation of Expanded Carrier Screening in Pregnant Women at Early Gestational Weeks: A Chinese Cohort Study
Clinical Implementation of Expanded Carrier Screening in Pregnant Women at Early Gestational Weeks: A Chinese Cohort Study Open
Demands for expanded carrier screening (ECS) are growing and ECS is becoming an important part of obstetrics practice and reproductive planning. The aim of this study is to evaluate the feasibility of a small-size ECS panel in clinical imp…
View article: Distribution of Methane Plumes on Cascadia Margin and Implications for the Landward Limit of Methane Hydrate Stability
Distribution of Methane Plumes on Cascadia Margin and Implications for the Landward Limit of Methane Hydrate Stability Open
Nearly 3,500 methane bubble streams, clustered into more than 1,300 methane emission sites, have been identified along the US Cascadia margin, derived both from archived published data and 2011, 2016–2018 dedicated multibeam surveys using …
View article: Expanded carrier screening for recessive genetic disorders: a review
Expanded carrier screening for recessive genetic disorders: a review Open
View article: Ocean sound levels in the northeast Pacific recorded from an autonomous underwater glider
Ocean sound levels in the northeast Pacific recorded from an autonomous underwater glider Open
Ocean gliders are a quiet and efficient mobile autonomous platform for passive acoustic monitoring and oceanographic measurements in remote marine environments. During July 20-August 6 2012, we used a Teledyne Webb Research Slocum G2 glide…
View article: Hydroacoustic, Meteorologic and Seismic Observations of the 2016 Nansen Ice Shelf Calving Event and Iceberg Formation
Hydroacoustic, Meteorologic and Seismic Observations of the 2016 Nansen Ice Shelf Calving Event and Iceberg Formation Open
On April 7, 2016 the Nansen ice shelf (NIS) front calved into two icebergs, the first large-scale calving event in >30 years. Three hydrophone moorings were deployed seaward of the NIS in December 2015 and over the following months recorde…
View article: A pulsed-air model of blue whale B call vocalizations
A pulsed-air model of blue whale B call vocalizations Open
View article: Identification of fragile X pre-mutation carriers in the Chinese obstetric population using a robust FMR1 polymerase chain reaction assay: implications for screening and prenatal diagnosis
Identification of fragile X pre-mutation carriers in the Chinese obstetric population using a robust FMR1 polymerase chain reaction assay: implications for screening and prenatal diagnosis Open
The overall prevalence of pre-mutation and asymptomatic full-mutation carriers in the Chinese pregnant population was one in 883, detected by a new FMR1 polymerase chain reaction assay.
View article: Obstetricians should get ready for expanded carrier screening
Obstetricians should get ready for expanded carrier screening Open
Single-gene disorders, although individually very rare, collectively affect about 10 in 1000 live births globally,1 and account for 20% of infant mortality and 18% of paediatric hospitalisations.2 These figures are likely to increase furth…
View article: P02.10: Twin anemia–polycythemia sequence: a clinical analysis of 7 cases
P02.10: Twin anemia–polycythemia sequence: a clinical analysis of 7 cases Open
To summarise and analyse the clinical characteristics including ultrasound features, prenatal characteristics, diagnosis, treatments and outcomes of the Twin Anemia–Polycythemia Sequence (TAPS) to improve the recognition of the disease. We…
View article: Canadian Academy of Geriatric Psychiatry 2015 Annual Scientific Meeting Abstracts
Canadian Academy of Geriatric Psychiatry 2015 Annual Scientific Meeting Abstracts Open
View article: AGING-RELATED POLICY, ECONOMIC WELL-BEING, EMPLOYMENT AND RETIREMENT ELDER BABY BOOMERS AND FINANCIAL EXPLOITATION
AGING-RELATED POLICY, ECONOMIC WELL-BEING, EMPLOYMENT AND RETIREMENT ELDER BABY BOOMERS AND FINANCIAL EXPLOITATION Open
Introduction: Many older adults report that self-tracking their physical activity (PA) influences their overall approach to health.Despite widespread availability of wearable devices and mobile health applications, older adults report doin…
View article: Cervical pessary placement for prevention of preterm birth in unselected twin pregnancies: a randomized controlled trial
Cervical pessary placement for prevention of preterm birth in unselected twin pregnancies: a randomized controlled trial Open
View article: Randomized trial of anaesthetic interventions in external cephalic version for breech presentation
Randomized trial of anaesthetic interventions in external cephalic version for breech presentation Open
View article: Association between PDCD1 Gene Polymorphisms and Risk of Systemic Lupus Erythematosus in Three Main Ethnic Groups of the Malaysian Population
Association between PDCD1 Gene Polymorphisms and Risk of Systemic Lupus Erythematosus in Three Main Ethnic Groups of the Malaysian Population Open
The programmed cell death 1 (PDCD1) gene encodes for the PD-1 (programmed death 1) molecule, which negatively regulates self-reactive T- and B-cells in the maintenance of peripheral tolerance. A previous report had shown the development of…
View article: Long‐term explosive degassing and debris flow activity at West Mata submarine volcano
Long‐term explosive degassing and debris flow activity at West Mata submarine volcano Open
West Mata is a 1200 m deep submarine volcano where explosive boninite eruptions were observed in 2009. The acoustic signatures from the volcano's summit eruptive vents Hades and Prometheus were recorded with an in situ (~25 m range) hydrop…
View article: Non‐invasive prenatal testing for trisomies 21, 18 and 13: clinical experience from 146 958 pregnancies
Non‐invasive prenatal testing for trisomies 21, 18 and 13: clinical experience from 146 958 pregnancies Open
Objectives To report the clinical performance of massively parallel sequencing‐based non‐invasive prenatal testing ( NIPT ) in detecting trisomies 21, 18 and 13 in over 140 000 clinical samples and to compare its performance in low‐risk an…
View article: Long-term Explosive Degassing, Debris Flows and Volatile Release at West Mata Submarine Volcano
Long-term Explosive Degassing, Debris Flows and Volatile Release at West Mata Submarine Volcano Open
West Mata is a 1200 m deep submarine volcano where explosive boninite eruptions were observed in 2009. The acoustic signatures from the volcano’s summit eruptive vents Hades and Prometheus were recorded with an in situ (~25m range) hydroph…