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View article: Evaluation of PADI4 (Human Peptidyl Arginine Deiminase Type 4) levels in patients with type 2 diabetes mellitus with/without complications
Evaluation of PADI4 (Human Peptidyl Arginine Deiminase Type 4) levels in patients with type 2 diabetes mellitus with/without complications Open
Purpose: Human peptidyl arginine deiminase 4 (PADI4) transforms arginine residues on histone tails to citrulline. Recently, researchers have studied PADI4 in inflammation, infection, cancer, and autoimmune disorders. PADI4 also modulates t…
View article: Clinical Manifestations, Treatment Characteristics and Clinical Outcome in Patients with Acquired Thrombotic Thrombocytopenic Purpura (aTTP) in the Real-World Setting: An Interim Analysis of the Turkish aTTP Registry
Clinical Manifestations, Treatment Characteristics and Clinical Outcome in Patients with Acquired Thrombotic Thrombocytopenic Purpura (aTTP) in the Real-World Setting: An Interim Analysis of the Turkish aTTP Registry Open
This interim analysis of the nationwide Turkish iTTP Registry study provides valuable data on real-world clinical practices in the diagnosis and management of iTTP at different hematology clinics across the country.
View article: Does the level of oxidative stress and genotoxicity increase in patients with acute myeloid leukemia?
Does the level of oxidative stress and genotoxicity increase in patients with acute myeloid leukemia? Open
Purpose: The present study evaluates the levels of oxidative stress and DNA damage in patients diagnosed with acute myeloid leukemia (AML; newly diagnosed patients and patients in remission) compared to healthy controls. Materials and meth…
View article: Combined and alone apoptotic effects of Ankaferd hemostat and silver nanoparticles on chronic myeloid leukemia (CML) cell line K562
Combined and alone apoptotic effects of Ankaferd hemostat and silver nanoparticles on chronic myeloid leukemia (CML) cell line K562 Open
Purpose: This study aimed to evaluate the effects of Ankaferd hemostat (ABS; Ankaferd Blood Stopper®) and silver nanoparticles (AgNPs), alone or in combination, on human chronic myeloid leukemia (CML) cells. Materials and methods: The cyto…
View article: Enhancing Hematopoietic Stem Cell Transplantation Success: The Crucial Role of Architectural Design in Transplant Units and Hematology Departments
Enhancing Hematopoietic Stem Cell Transplantation Success: The Crucial Role of Architectural Design in Transplant Units and Hematology Departments Open
Aim: This paper aims to explore the critical role of architectural design in Hematopoietic Stem Cell Transplantation (HSCT) procedures, focusing on how various aspects of design influence patient outcomes, staff efficiency, infection contr…
View article: Investigation of erythrocyte membrane lipid profile, oxidative stress and dna damage parameters in patients with chronic lymphoid leukemia
Investigation of erythrocyte membrane lipid profile, oxidative stress and dna damage parameters in patients with chronic lymphoid leukemia Open
Purpose: Chronic lymphocytic leukemia (CLL) is the most seen type of leukemia in adults. There are few biomarkes that are used for better understanding how oxidative stress is involved in the pathophysiology of hematologic malignency.We ai…
View article: Hematopoetik Kök Hücre Nakli Başarısını Artırma: Nakil Üniteleri ve Hematoloji Bölümlerindeki Mimarlık Tasarımının Kritik Rolü
Hematopoetik Kök Hücre Nakli Başarısını Artırma: Nakil Üniteleri ve Hematoloji Bölümlerindeki Mimarlık Tasarımının Kritik Rolü Open
Amaç: Bu çalışmanın amacı, Hematopoietik Kök Hücre Nakli (HSCT) prosedürlerinde mimari tasarımın kritik rolünü araştırmak ve tasarımın hasta sonuçları, personel verimliliği, enfeksiyon kontrolü ve genel güvenlik üzerindeki çeşitli etkileri…
View article: Complications of imaging-assisted port catheters and factors affecting complications
Complications of imaging-assisted port catheters and factors affecting complications Open
Purpose: The aim of this research paper is to comprehensively investigate the complications associated with imaging-assisted port catheters (IAPCs) and identify the factors influencing the occurrence of these complications.
Materials and…
View article: Metachronous or Synchronous Presentation of Acute Myeloid Leukemia and Lung Cancer: A Single Center Experience
Metachronous or Synchronous Presentation of Acute Myeloid Leukemia and Lung Cancer: A Single Center Experience Open
Aims: Acute myeloid leukemia (AML) is the most common type of leukemia in adults. Lung cancer is one of the most common types of cancer. The concomitant presentation of AML and lung cancer is extremely rare. This study aimed to report a ca…
View article: Effects of Gonadotropins on Blood, Bone Marrow, and Spleen in Cyclophosphamide-Exposed Rats
Effects of Gonadotropins on Blood, Bone Marrow, and Spleen in Cyclophosphamide-Exposed Rats Open
Cyclophosphamide (CTX) is an effective chemotherapeutic agent. Gonadotropins are molecules with various actions. We investigated the effects of gonadotropins on the peripheral blood, bone marrow, and spleen in rats given CTX. Three groups …
View article: Kültür Mantarından (Agaricus bisporus) İzole Edilen Kitosanın Hemostatik ve Antimikrobiyal Yara Örtüsünde Kullanımın Araştırılması
Kültür Mantarından (Agaricus bisporus) İzole Edilen Kitosanın Hemostatik ve Antimikrobiyal Yara Örtüsünde Kullanımın Araştırılması Open
The objective of this study was to examine the antimicrobial and hemostatic properties of chitosan derived from Agaricus bisporus, with the intention of utilizing it in wound dressings. This study involved the extraction of chitin from Aga…
View article: The Electrospinning of Different Hemostatic Agents and Their Effectiveness
The Electrospinning of Different Hemostatic Agents and Their Effectiveness Open
The purpose of this study is to present effective solutions for severe bleeding and tissue damage occurring during situations such as conflicts, disasters, and crises. The aim is to produce nanofibers that can serve as a hemostatic wound d…
View article: A Multiple myeloma case with ascites
A Multiple myeloma case with ascites Open
Ascites is an unusual finding of multiple myeloma. It is a sign of poor prognosis and can be seen not only at the initial diagnosis, but also at any stage of the disease. In this case report, we present the peritoneal involvement of a rela…
View article: Radiation exposure in acute myeloid leukaemia, diffuse large B-cell lymphoma, and multiple myeloma patients in the first year following diagnosis
Radiation exposure in acute myeloid leukaemia, diffuse large B-cell lymphoma, and multiple myeloma patients in the first year following diagnosis Open
Introduction Radiological examinations are critical in the evaluation of patients with haematological malignancies for diagnosis and treatment. Any dose of radiation has been shown in studies to be harmful. In this regard, we assessed the …
View article: Predictive and prognostic value of serum vitamin b12 elevation in acute leukemia
Predictive and prognostic value of serum vitamin b12 elevation in acute leukemia Open
Purpose: In this study; we sought to assess whether elevated vitamin B12 levels during the course of diagnosis might be a predictor of acute leukemias.
Materials and Method: The study was prepared by retrospectively evaluating the anamnes…
View article: Turkey Real-Life Data: Demographic Features, Treatment Results and Effects of Comorbidities in Chronic Myeloid Leukemia
Turkey Real-Life Data: Demographic Features, Treatment Results and Effects of Comorbidities in Chronic Myeloid Leukemia Open
The response rates of CP-CML patients to the tyrosine kinase inhibitors were satisfactory. In addition to tolerability and side effect profiles of drugs, comorbidity status of patients should also be considered in treatment choice in CML p…
View article: The Haemostatic Effects of Ankaferd Blood Stopper® on Mammalian Brain Parenchyma: An Experimental Study
The Haemostatic Effects of Ankaferd Blood Stopper® on Mammalian Brain Parenchyma: An Experimental Study Open
Aim: Haemostasis is a vital stage for the success of the surgery. Although Ankaferd Blood Stopper
(ABS), a low-cost and reliable agent, is used in many surgeries, it is not yet available for use in the
intracranial area. This study aims …
View article: A Life-Saving Early Diagnosis of Burkitt Lymphoma Involving both Jaws, Misdiagnosed as Pericoronitis
A Life-Saving Early Diagnosis of Burkitt Lymphoma Involving both Jaws, Misdiagnosed as Pericoronitis Open
Purpose: Burkitt lymphoma (BL) is a highly aggressive and rare B-cell non-Hodgkin’s lymphoma. In this paper, a rare case of BL, involving both jaws, was presented. Case Report: A 24-year-old male patient was referred to our clinic with the…
View article: Covid-19 case with prolonged neutropenia
Covid-19 case with prolonged neutropenia Open
Bu yazıda sağlıklı bir erişkinde COVID-19 enfeksiyonu sırasında gelişen ve yaklaşık 1,5 ay devam eden nötropeni tablosunun takip ve tedavi sürecini sunuyoruz. Halsizlik ve eklem ağrısı şikayeti ile başvurusunda pcr pozitifliği ve laboratuv…
View article: Serum Hepcidin and Prohepcidin Levels in Nonfebrile and Febrile Neutropenia
Serum Hepcidin and Prohepcidin Levels in Nonfebrile and Febrile Neutropenia Open
Although there was no significant difference between afebnile neutropenia and neutropenic fever in patients in terms of hepcidin and prohepcidin levels, higher levels were found in both groups compared to the control group. Key Words: Hepc…
View article: Is CONUT score a prognostic index in patients with diffuse large cell lymphoma?
Is CONUT score a prognostic index in patients with diffuse large cell lymphoma? Open
High CONUT score reduces OS and PFS in DLBCL. CONUT score is an independent, strong prognostic index in patients with DLBCL.
View article: Evaluation of the achievement of hematologists to transfusion medicine education with self-assessment questionnaire in Turkey
Evaluation of the achievement of hematologists to transfusion medicine education with self-assessment questionnaire in Turkey Open
Background: Proper clinical use of blood and blood products requires competent theoretical and practical knowledge of transfusion medicine. The Curriculum Development and Standard Determination System Medical Specialization Board is prepar…
View article: Evaluation of the knowledge of intern doctors on transfusion medicine in Turkey
Evaluation of the knowledge of intern doctors on transfusion medicine in Turkey Open
Background: Proper clinical use of blood products requires competent theoretical and practical knowledge of transfusion medicine. In this study, we aimed to evaluate levels of transfusion medicine knowledge and attainment of educational ta…
View article: PB1933 CLINICAL FEATURES AND TREATMENT OUTCOMES OF CHRONIC PHASE‐CHRONIC MYELOID LEUKEMIA PATIENTS IN TURKEY: REAL‐WORLD DATA
PB1933 CLINICAL FEATURES AND TREATMENT OUTCOMES OF CHRONIC PHASE‐CHRONIC MYELOID LEUKEMIA PATIENTS IN TURKEY: REAL‐WORLD DATA Open
Background: Tyrosine kinase inhibitors (TKIs) have been standard‐of‐care for patients with chronic myeloid leukemia (CML) and improvements with TKIs have been obtained in survival rates. In Turkey, imatinib is the only reimbursed TKI for f…
View article: Combination therapy with azacitidine, etoposide, and cytarabine in the treatment of elderly acute myeloid leukemia patients
Combination therapy with azacitidine, etoposide, and cytarabine in the treatment of elderly acute myeloid leukemia patients Open
We concluded that combination therapy of Aza with Eto and ARA-C increases response rates, and prolong survival for this poor prognosed patient group. We believe that larger controlled studies investigating Aza combinations with other antil…
View article: Protective effect of Solanum tuberosum against the breakdown of red blood cells: an experimental study in burn injury model
Protective effect of Solanum tuberosum against the breakdown of red blood cells: an experimental study in burn injury model Open
Introduction: Anemia is known to be an important problem in burn injury. We aimed to investigate the protective effect of Solanum tuberosum (potatoes), against abnormal breakdown of erythrocytes in burn injury. Methods: Ninety-six male (9 …
View article: The Predictive Role of the Neutrophil/Lymphocyte Ratio in Survival with Multiple Myeloma: A Single Center Experience
The Predictive Role of the Neutrophil/Lymphocyte Ratio in Survival with Multiple Myeloma: A Single Center Experience Open
Neutrophil/lymphocyte ratio, which is associated with stage, performance status, and kidney functions, can be used in daily practice as a predictor for survival in multiple myeloma. Simply adding NLR to the routine charts may enrich our da…