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View article: Nocturnal respiratory support with nasal high flow in hypercapnic COPD: a randomised, crossover trial
Nocturnal respiratory support with nasal high flow in hypercapnic COPD: a randomised, crossover trial Open
Background Nasal high flow (NHF) is an established treatment option in acute respiratory failure and has been shown to increase the elimination of carbon dioxide (CO 2 ) in hypercapnic COPD patients. The aim of the study was to investigate…
View article: Effect of respiratory rate and size of cannula on pressure and dead-space clearance during nasal high flow in patients with COPD and acute respiratory failure
Effect of respiratory rate and size of cannula on pressure and dead-space clearance during nasal high flow in patients with COPD and acute respiratory failure Open
During nasal high flow (NHF) an increased breathing frequency, which is commonly observed in acute respiratory failure, can lead to decreased dead-space clearance. Higher NHF rates increase the clearance and reduce the rebreathing which ma…
View article: Mask humidity during CPAP: influence of ambient temperature, heated humidification and heated tubing
Mask humidity during CPAP: influence of ambient temperature, heated humidification and heated tubing Open
Clinically-relevant reductions in aH were documented during CPAP given under winter conditions. The addition of heated humidification, using a heated tube to avoid condensation is recommended to increase aH, which could be useful in CPAP u…
View article: A randomized controlled trial to validate the Alice PDX ambulatory device
A randomized controlled trial to validate the Alice PDX ambulatory device Open
In a population with a high suspicion of OSA, the Alice PDX showed a high level of diagnostic agreement with a simultaneous PSG and performed valid home diagnostic studies for OSA. If manually scored, the portable device can be used by sle…
View article: Non-invasive ventilation with intelligent volume-assured pressure support versus pressure-controlled ventilation: effects on the respiratory event rate and sleep quality in COPD with chronic hypercapnia
Non-invasive ventilation with intelligent volume-assured pressure support versus pressure-controlled ventilation: effects on the respiratory event rate and sleep quality in COPD with chronic hypercapnia Open
Our results show that IVAPS NIV allows application of higher nocturnal ventilation pressures versus ST without affecting sleep quality or inducing ventilation- associated events.
View article: Nasal high flow reduces dead space
Nasal high flow reduces dead space Open
Recent studies show that nasal high flow (NHF) therapy can support ventilation in patients with acute or chronic respiratory disorders. Clearance of dead space has been suggested as being the key mechanism of respiratory support with NHF t…
View article: Telemonitoring of home exercise cycle training in patients with COPD
Telemonitoring of home exercise cycle training in patients with COPD Open
Telemonitoring is a simple method to enhance home exercise training and physical activity, improving health-related quality of life.
View article: Nasal high flow reduces hypercapnia by clearance of anatomical dead space in a COPD patient
Nasal high flow reduces hypercapnia by clearance of anatomical dead space in a COPD patient Open
Chronic obstructive pulmonary disease (COPD) with hypercapnia is associated with increased mortality. Non-invasive ventilation (NIV) can lower hypercapnia and ventilator loads but is hampered by a low adherence rate leaving a majority of p…