Ullrich Jahn
YOU?
Author Swipe
View article: A Synthetic Approach to Sterically Hindered P‐Chiral Phosphine Ligands and Their Applications for Asymmetric Gold Catalysis
A Synthetic Approach to Sterically Hindered P‐Chiral Phosphine Ligands and Their Applications for Asymmetric Gold Catalysis Open
In contrast to wide‐ranging applications of axially and planar chiral bidentate phosphine ligands, the development of P‐chiral monophosphine ligands is much less advanced. Here a practical method is outlined for the synthesis of P‐chiral b…
View article: Beyond Neuroprostanes: Total Synthesis and Epilipidomic Studies of a Novel Cyclopentenone Metabolite of Docosahexaenoic Acid
Beyond Neuroprostanes: Total Synthesis and Epilipidomic Studies of a Novel Cyclopentenone Metabolite of Docosahexaenoic Acid Open
Neuroprostanes (NeuroPs) are bioactive oxylipins formed in vivo from docosahexaenoic acid (DHA), the main polyunsaturated fatty acid of the human brain, by a nonenzymatic auto‐oxidative process as mixtures of regio‐ and diastereoisomers. T…
View article: An update of isoprostanoid nomenclature
An update of isoprostanoid nomenclature Open
Polyunsaturated fatty acids (PUFAs) play numerous roles in living organisms but are also prone to rapid aerobic oxidation, resulting in the production of a wide range of isomeric metabolites called oxylipins. Among these, isoprostanes, dis…
View article: Foldamers controlled by functional triamino acids: structural investigation of α/γ-hybrid oligopeptides
Foldamers controlled by functional triamino acids: structural investigation of α/γ-hybrid oligopeptides Open
Peptide-like foldamers controlled by normal amide backbone hydrogen bonding have been extensively studied, and their folding patterns largely rely on configurational and conformational constraints induced by the steric properties of backbo…
View article: Primary and Secondary Amines by Flavin‐Photocatalyzed Consecutive Desulfonylation and Dealkylation of Sulfonamides
Primary and Secondary Amines by Flavin‐Photocatalyzed Consecutive Desulfonylation and Dealkylation of Sulfonamides Open
Alkane‐, arene‐, and perfluoroalkanesulfonyl groups are widely used in organic synthesis to protect amino functionalities or to facilitate their installation. Protection of amino functions by a sulfonyl group to form sulfonamides is advant…
View article: Concise Total Syntheses of (+)‐Brefeldin A, Diastereomers and Analogs and Their Biological Activity
Concise Total Syntheses of (+)‐Brefeldin A, Diastereomers and Analogs and Their Biological Activity Open
Brefeldin A is an important natural product and biochemical tool with cell‐modulating and other diverse biological activities. To explore its chemical space, a generally applicable strategy for total syntheses of naturally occurring (+)‐br…
View article: CCDC 2097883: Experimental Crystal Structure Determination
CCDC 2097883: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2097881: Experimental Crystal Structure Determination
CCDC 2097881: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2097885: Experimental Crystal Structure Determination
CCDC 2097885: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2097882: Experimental Crystal Structure Determination
CCDC 2097882: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2070235: Experimental Crystal Structure Determination
CCDC 2070235: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2070234: Experimental Crystal Structure Determination
CCDC 2070234: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2070236: Experimental Crystal Structure Determination
CCDC 2070236: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2047587: Experimental Crystal Structure Determination
CCDC 2047587: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Sulfonyl Nitrene and Amidyl Radical: Structure and Reactivity
Sulfonyl Nitrene and Amidyl Radical: Structure and Reactivity Open
Photocatalytic generation of nitrenes and radicals can be used to tune or even control their reactivity. Photocatalytic activation of sulfonyl azides leads to the elimination of N 2 and the resulting reactive species initiate C−H activatio…
View article: A Diastereoselective Catalytic Approach to Pentasubstituted Pyrrolidines by Tandem Anionic‐Radical Cross‐Over Reactions
A Diastereoselective Catalytic Approach to Pentasubstituted Pyrrolidines by Tandem Anionic‐Radical Cross‐Over Reactions Open
Pentasubstituted pyrrolidines are ubiquitous constituents of natural products and drugs, however the access options to them especially with respect to absolute and relative stereochemistry are not well developed. We report an asymmetric sy…
View article: Design of Novel Uncharged Organic Superbases: Merging Basicity and Functionality
Design of Novel Uncharged Organic Superbases: Merging Basicity and Functionality Open
ConspectusOne of the constant challenges of synthetic chemistry is the molecular design and synthesis of nonionic, metal-free superbases as chemically stable neutral organic compounds of moderate molecular weight, intrinsically high thermo…
View article: Cover Feature: First Total Synthesis of Phytoprostanes with Prostaglandin‐Like Configuration, Evidence for Their Formation in Edible Vegetable Oils and Orienting Study of Their Biological Activity (Chem. Eur. J. 37/2021)
Cover Feature: First Total Synthesis of Phytoprostanes with Prostaglandin‐Like Configuration, Evidence for Their Formation in Edible Vegetable Oils and Orienting Study of Their Biological Activity (Chem. Eur. J. 37/2021) Open
Phytoglandins from the reaction flask enable their identification in Nature. Hypothetical plant-based prostaglandin analogs were obtained by a 15-step asymmetric total synthesis. They were applied as an analytical standard in a detailed LC…
View article: α,γ-Dioxygenated amides via tandem Brook rearrangement/radical oxygenation reactions and their application to syntheses of γ-lactams
α,γ-Dioxygenated amides via tandem Brook rearrangement/radical oxygenation reactions and their application to syntheses of γ-lactams Open
Pyrrolidones are common heterocyclic fragments in various biologically active compounds. Here, a two-step radical-based approach to γ-lactams bearing three to four stereocenters starting from epoxides, N -allylic silylacetamides and TEMPO …
View article: CCDC 1968542: Experimental Crystal Structure Determination
CCDC 1968542: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1968545: Experimental Crystal Structure Determination
CCDC 1968545: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1968544: Experimental Crystal Structure Determination
CCDC 1968544: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1968537: Experimental Crystal Structure Determination
CCDC 1968537: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1968538: Experimental Crystal Structure Determination
CCDC 1968538: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1968540: Experimental Crystal Structure Determination
CCDC 1968540: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1968543: Experimental Crystal Structure Determination
CCDC 1968543: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 1968541: Experimental Crystal Structure Determination
CCDC 1968541: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: First Total Syntheses of Novel Non‐Enzymatic Polyunsaturated Fatty Acid Metabolites and Their Identification in Edible Oils
First Total Syntheses of Novel Non‐Enzymatic Polyunsaturated Fatty Acid Metabolites and Their Identification in Edible Oils Open
Oxidative stress (OS) is an in vivo process leading to free radical overproduction, which triggers polyunsaturated fatty acid (PUFA) peroxidation resulting in the formation of racemic non‐enzymatic oxygenated metabolites. As potential biom…