Explanipedia

Acute Gas Toxicity at Work: A Tale of Two Cases with Review of Literature Open

Sanjay Kumar, Singh Jitender Pratap, Kishore Manjari, Garg HM · 2025

Hydrogen sulphide [ H2S] is created when sewage material breaks down. The well-known "rotten egg" odour is linked to H2S at low quantities. It is a colourless and odourless gas that, at greater quantities, can cause cerebral and respirator…

Exploring biochemical responses and cellular adaptations of Chlorella sorokiniana to polyethylene microplastic exposure Open

Jyoti Rawat, Pooja Bhatnagar, Abhilasha Mishra, Manisha Nanda, Prateek Gururani , et al. · 2025

Interaction of Anionic Surfactants with Native and Partially Unfolded RNase A: Binding Kinetics, Structural Changes, and Stability Open

Sanjay Kumar, N. Prakash Prabhu · 2025

In protein-surfactant interactions, the alkyl chain length of surfactants and the surface-exposed residues of proteins play essential roles in binding and unfolding. To investigate this, the interactions of sodium octyl (SOS), decyl (SDeS)…

Interaction of Anionic Surfactants with Native and Partially-Unfolded Rnase a: Binding Kinetics, Structural Changes, and Stability Open

N. Prakash Prabhu, Sanjay Kumar · 2025

Maximum Solar Energy Tracking Leverage High-DoF Robotics System with Deep Reinforcement Learning Open

Allen Jiang, Kangtong Mo, Satoshi Fujimoto, Michael D. Taylor, Sanjay Kumar , et al. · 2024

Solar trajectory monitoring is a pivotal challenge in solar energy systems, underpinning applications such as autonomous energy harvesting and environmental sensing. A prevalent failure mode in sustained solar tracking arises when the pred…

Maximum Solar Energy Tracking Leverage High-DoF Robotics System with Deep Reinforcement Learning Open

Allen Jiang, Kangtong Mo, Satoshi Fujimoto, Michael D. Taylor, Sanjay Kumar , et al. · 2024

Solar trajectory monitoring is a pivotal challenge in solar energy systems, underpinning applications such as autonomous energy harvesting and environmental sensing. A prevalent failure mode in sustained solar tracking arises when the pred…

Soil Phosphorus Distribution across Diverse Land Use Systems: A Comprehensive Review Open

N N Annappa, R. K. Murthy, N.R. Bhavya, K. Govinda, Sanjay Kumar · 2024

Phosphorus (P) is a crucial nutrient necessary for healthy plant growth. While soils typically contain a sufficient total amount of P (200-300 mg P kg–1), less than 1% of it is readily available to plants. In India, despite an adequate tot…

Caveolin-1 Knockout Mitigates Breast Cancer Metastasis to the Lungs via Integrin α3 Dysregulation. Open

Joseph Francis, Dhirendra Kumar Singh, Rashmi Pathak, Abhishek Pandit, Philip J. Ebenezer , et al. · 2023

Caveolin-1 (Cav-1) is a critical lipid raft protein playing divergent roles as both a tumor suppressor and promoter. While its role in tumorigenesis, progression, and metastasis is recognized, explicit contribution of Cav-1 to the onset of…

Untapped potential of non-conventional rubus species: bioactivity, nutrition, and livelihood opportunities Open

Saurav Chandra Bhatt, Bindu Naik, Vijay Kumar, Arun Kumar Gupta, Sanjay Kumar , et al. · 2023

Deep learning-based cell profiling based on neuronal morphology Open

Qiang Liu, Francesca J. Nicholls, Helen Rowland, Adrià Dangla-Valls, Shuhan Li , et al. · 2023

Treatment of neurons with β-amyloid peptide (Aβ 1-42 ) has been widely used as a model to interrogate the cellular and molecular mechanisms underlying Alzheimer’s disease, and as an assay system to identify drugs that reverse or block dise…

Can one detect intermediate denaturation states of DNA sequences by following the equilibrium open–close dynamic fluctuations of a single base pair? Open

Keerti Chauhan, Amit Raj Singh, Sanjay Kumar, Rony Granek · 2022

Melting of DNA sequences may occur through a few major intermediate states, whose influence on the melting curve has been discussed previously, while their effect on the kinetics has not been explored thoroughly. Here, we chose a simple DN…

Yeast Crf1p: An activator in need is an activator indeed Open

Sanjay Kumar, Muneera Mashkoor, Anne Grove · 2021

Intricate regulation of ribosome biogenesis genes in response to mTORC1 signaling Open

Sanjay Kumar, Muneera Mashkoor, Priya Balamurugan, Anne Grove · 2021

Summary Genes encoding ribosomal proteins are repressed in response to inhibition of mTORC1. In Saccharomyces cerevisiae , this involves dissociation of the activator Ifh1p in a process that depends on Utp22p, a protein that also functions…

Synthesis and Crystal Structure of 2-[(4-Chlorobenzoyl)amino]-3-(4-formylphenyl)prop-2-enoic Acid Open

Sanjay Kumar, K. Subbulakshmi, B. Narayana, B.K. Sarojini, Sumati Anthal , et al. · 2017

2-[(4-Chlorobenzoyl)amino]-3-(4-formylphenyl)prop-2-enoic acid (C 17 H 12 ClNO 4 ) crystallizes in the orthorhombic space group Pbcn with unit cell parameters: a = 17.2460(13)Å, b = 9.6735(8) Å, c = 19.953(2)Å, α = β = γ = 90.00o and Z=8.D…

SYNTHESIS AND CRYSTAL STRUCTURE OF (E)-3-(4-BUTOXYPHENYL)-1-(NAPHTHALEN-1-YL)PROP-2-EN-1-ONE Open

Sanjay Kumar, A. Jayashree, B. Narayana, B.K. Sarojini, László Kótai , et al. · 2017

Chalcone derivative (E)-3-(4-Butoxyphenyl)-1-(naphthalen-1-yl)prop-2-en-1-one (C23 H22 O2) crystallizes in monoclinic system with space group 'P 21/c ' and unit cell parameters: a = 15.1595(14) Å, b = 7.6644(7) Å, c = 15.8634(15) Å, b = 96…

SYNTHESIS AND CRYSTALLOGRAPHY OF A DIMERIZED CHALCONE DERIVATIVE Open

Sanjay Kumar, Vinutha V. Salian, B. Narayana, B.K. Sarojini, Sumati Anthal , et al. · 2017

The chalcone derivative, [3-(4-Chlorobenzoyl)-2,4-bis((4-propan-2-yl)phenyl)cyclobutyl](4-chlorophenyl)methan one (C36H34Cl2O2), crystallizes in the monoclinic crystal system with space group P21/c and unit cell parameters: a = 18.4793(1)Å…

Periodically driven DNA: Theory and simulation Open

Sanjay Kumar, Ravinder Kumar, Wolfhard Janke · 2016

We propose a generic model of driven DNA under the influence of an oscillatory force of amplitude F and frequency ν and show the existence of a dynamical transition for a chain of finite length. We find that the area of the hysteresis loop…

Rupture of DNA aptamer: New insights from simulations Open

Rakesh Kumar Mishra, Shesh Nath, Sanjay Kumar · 2015

Base-pockets (non-complementary base-pairs) in a double-stranded DNA play a crucial role in biological processes. Because of thermal fluctuations, it can lower the stability of DNA, whereas, in case of DNA aptamer, small molecules, e.g., a…

On the rupture of DNA molecule Open

Rakesh Kumar Mishra, Tushar Modi, Debasis Giri, Sanjay Kumar · 2015

Using Langevin Dynamic simulations, we study effects of the shear force on the rupture of a double stranded DNA molecule. The model studied here contains two single diblock copolymers interacting with each other. The elastic constants of i…

Complete Genome Sequence Analysis of Bacillus subtilis T30 Open

Shuang-yong Xu, Matthew Boitano, Tyson A. Clark, Tamas Vincze, Alexey Fomenkov , et al. · 2015

The complete genome sequence of Bacillus subtilis T30 was determined by SMRT sequencing. The entire genome contains 4,138 predicted genes. The genome carries one intact prophage sequence (37.4 kb) similar to Bacillus phage SPBc2 and one in…

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