Uet Yu
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View article: Prognostic impact of donor KIR genotypes on clinical outcomes in pediatric allogeneic hematopoietic stem cell transplantation
Prognostic impact of donor KIR genotypes on clinical outcomes in pediatric allogeneic hematopoietic stem cell transplantation Open
Prognostic Impact of Donor KIR Genotypes on Clinical Outcomes in Pediatric Allogeneic Hematopoietic Stem Cell Transplantation Background: Donor killer immunoglobulin-like receptor (KIR) genotypes critically modulate natural killer (NK) cel…
View article: Circulating tumor cells and clusters as liquid biomarkers for the diagnosis and prognosis of neuroblastoma
Circulating tumor cells and clusters as liquid biomarkers for the diagnosis and prognosis of neuroblastoma Open
View article: Development of a prognostic model incorporating a cuproptosis-related signature and CNN3 as a predictor in childhood acute myelocytic leukemia
Development of a prognostic model incorporating a cuproptosis-related signature and CNN3 as a predictor in childhood acute myelocytic leukemia Open
Background Childhood acute myeloid leukemia (cAML) is the second most common pediatric blood cancer, with high heterogeneity and poor prognosis. Recent studies have highlighted cuproptosis, a newly discovered form of programmed cell death …
View article: TRIM8 as a predictor for prognosis in childhood acute lymphoblastic leukemia based on a signature of neutrophil extracellular traps
TRIM8 as a predictor for prognosis in childhood acute lymphoblastic leukemia based on a signature of neutrophil extracellular traps Open
Background Neutrophil extracellular traps (NETs) can be attributed to the metastasis, occurrence, and immune evasion of cancer cells. We investigated the prognostic value of NET-related genes in childhood acute lymphoblastic leukemia (cALL…
View article: Genome-wide methylation and gene-expression analyses in thalassemia
Genome-wide methylation and gene-expression analyses in thalassemia Open
Thalassemia is the most common autosomal genetic disorder in humans. The pathogenesis of thalassemia is principally due to the deletion or mutation of globin genes that then leads to disorders in globin-chain synthesis, and its predominant…
View article: Circulating Cell-in-Cell Tumor Cells with Neutrophil Signature are Hematogenous Metastasis-Initiating Cells
Circulating Cell-in-Cell Tumor Cells with Neutrophil Signature are Hematogenous Metastasis-Initiating Cells Open
View article: Surveillance and Outcomes of Pediatric Hematopoietic Stem Cell Transplantation Recipients During the Recent COVID-19 Outbreak in China
Surveillance and Outcomes of Pediatric Hematopoietic Stem Cell Transplantation Recipients During the Recent COVID-19 Outbreak in China Open
This study provides insights into clinical features, therapeutic measures, and outcomes of pediatric HSCT recipients following COVID-19 infection in a large HSCT center in China. These findings contribute to our understanding of COVID-19 i…
View article: Outcomes and Risk Factor Analysis of Plastic Bronchitis Among 321 Children with Influenza Pneumonia After Bronchoscopy Examination
Outcomes and Risk Factor Analysis of Plastic Bronchitis Among 321 Children with Influenza Pneumonia After Bronchoscopy Examination Open
Influenza virus infection is linked to PB development in children. Identifying risk factors and early intervention such as bronchoscopy can improve the prognosis of children with PB.
View article: Successful Treatment of Massive Intractable Pericardial Effusion with Tocilizumab in a Child Undergone Allogeneic Hematopoietic Stem Cell Transplantation
Successful Treatment of Massive Intractable Pericardial Effusion with Tocilizumab in a Child Undergone Allogeneic Hematopoietic Stem Cell Transplantation Open
A 4-year-old child with β-thalassemia major underwent allogeneic hematopoietic stem cell transplantation (HSCT) on August 30, 2022 from a male haploidentical donor. He developed massive pericardial effusion (PE) secondary to a pulmonary in…
View article: Successful Treatment of Rare Pulmonary Coprinopsis cinerea Infection in a 17-Year-Old Female After Hematopoietic Stem Cell Transplantation: A Case Report
Successful Treatment of Rare Pulmonary Coprinopsis cinerea Infection in a 17-Year-Old Female After Hematopoietic Stem Cell Transplantation: A Case Report Open
Invasive fungal infections (IFIs) are among the most severe complications in recipients of hematopoietic stem cell transplantation (HSCT) recipients and in patients with hematological malignancies. An increasing number of uncommon fungal i…
View article: Emergence of Antimicrobial Resistance in Uropathogens in Butembo, Democratic Republic of Congo: A 5 Years Retrospective Study
Emergence of Antimicrobial Resistance in Uropathogens in Butembo, Democratic Republic of Congo: A 5 Years Retrospective Study Open
Background Antimicrobial resistance is a global challenging issue in children and adults. Finding the extent of resistance is the first step in finding an appropriate way to combat it. This study aimed to assess the antibiotic resistance p…
View article: A Retrospective Analysis of the Therapeutic Outcomes of 117 Neuroblastoma Patients Treated at a Single Pediatric Oncology Center in China
A Retrospective Analysis of the Therapeutic Outcomes of 117 Neuroblastoma Patients Treated at a Single Pediatric Oncology Center in China Open
Objective Recent therapeutic advances have greatly enhanced the survival rates of patients with neuroblastoma (NB). However, the outcomes of neuroblastoma patients in China, particularly those with high-risk (HR) NB, remain limited. Method…
View article: Multi-omics association analysis reveals interactions between the oropharyngeal microbiome and the metabolome in pediatric patients with influenza A virus pneumonia
Multi-omics association analysis reveals interactions between the oropharyngeal microbiome and the metabolome in pediatric patients with influenza A virus pneumonia Open
Children are at high risk for influenza A virus (IAV) infections, which can develop into severe illnesses. However, little is known about interactions between the microbiome and respiratory tract metabolites and their impact on the develop…
View article: circKL inhibits the growth and metastasis of kidney cancer by sponging miR‑182‑5p and upregulating FBXW7
circKL inhibits the growth and metastasis of kidney cancer by sponging miR‑182‑5p and upregulating FBXW7 Open
Circular RNAs (circRNAs) are a type of non-coding RNA with important roles in the regulation of various biological processes involved in malignant progression. However, the potential molecular mechanisms and roles of circRNAs in kidney can…
View article: Cytomegalovirus (CMV)-specific cytotoxic T lymphocyte therapy resolve CMV diseases and refractory CMV infections in paediatric recipients of allogeneic haematopoietic stem cell transplantation
Cytomegalovirus (CMV)-specific cytotoxic T lymphocyte therapy resolve CMV diseases and refractory CMV infections in paediatric recipients of allogeneic haematopoietic stem cell transplantation Open
View article: Cytomegalovirus Infection and the Implications of Drug-Resistant Mutations in Pediatric Allogeneic Hematopoietic Stem Cell Transplant Recipients: A Retrospective Study from a Tertiary Hospital in China
Cytomegalovirus Infection and the Implications of Drug-Resistant Mutations in Pediatric Allogeneic Hematopoietic Stem Cell Transplant Recipients: A Retrospective Study from a Tertiary Hospital in China Open
View article: Precisione Treatment for Parvovirus B19 Infection After Hematopoietic Stem Cell Transplantation: a Case Report and Review of the Literature
Precisione Treatment for Parvovirus B19 Infection After Hematopoietic Stem Cell Transplantation: a Case Report and Review of the Literature Open
Background: Cytopenia due to parvovirus B19 (PVB19) infection has rarely been reported in recipients of thalassemia major after hematopoietic stem cell transplantation (HSCT). Most of the reported cases were patients undergone solid organ …
View article: c.3G>A mutation in the CRYAB gene that causes fatal infantile hypertonic myofibrillar myopathy in the Chinese population
c.3G>A mutation in the CRYAB gene that causes fatal infantile hypertonic myofibrillar myopathy in the Chinese population Open
Infantile hypertonic myofibrillar myopathy is characterized by the rapid development of rigid muscles and respiratory insufficiency soon after birth, with very high mortality. It is extremely rare, and only a few cases having been reported…
View article: Case Report: Myeloid Sarcoma Development During Treatment for B Cell Lymphoblastic Lymphoma in a Boy with KRAS/NRAS Gene Mutations
Case Report: Myeloid Sarcoma Development During Treatment for B Cell Lymphoblastic Lymphoma in a Boy with KRAS/NRAS Gene Mutations Open
Here, we report a rare case of a 12-year-old boy who was initially diagnosed with B cell lymphoblastic lymphoma (BLBL) and developed myeloid sarcoma (MS) eight months after chemotherapy. Next-generation sequencing (NGS) showed mutations of…
View article: Co-Transplantation of Haploidentical Stem Cells and a Dose of Unrelated Cord Blood in Pediatric Patients with Thalassemia Major
Co-Transplantation of Haploidentical Stem Cells and a Dose of Unrelated Cord Blood in Pediatric Patients with Thalassemia Major Open
Allogeneic stem cell transplantation is a cure for patients suffering from thalassemia major (TM). Historically, patients were limited by the selection of donors, while the advancement of haploidentical stem cell transplantation (haplo-SCT…
View article: <p>Identification and Treatment of Tuberculosis in Pediatric Recipients of Allogeneic Hematopoietic Stem Cell Transplantation: Case Series and Review of the Literature</p>
Identification and Treatment of Tuberculosis in Pediatric Recipients of Allogeneic Hematopoietic Stem Cell Transplantation: Case Series and Review of the Literature Open
Tuberculosis must be carefully evaluated in all pediatric patients that receive hematopoietic stem cell transplantation, regardless of the identification of other pathogens. Prophylactic tuberculosis therapy should be considered for high-r…
View article: Massive hydatid cysts in the lung and liver of a 4‐year‐old boy
Massive hydatid cysts in the lung and liver of a 4‐year‐old boy Open
Hydatids may persist for years if left undiagnosed. Early identification is challenging, especially in patients from nonendemic regions. It is crucial for clinicians to be aware of the presence of the disease to avoid devastating outcomes.
View article: Evaluation of the vitamin D and biomedical statuses of young children with β-thalassemia major at a single center in southern China
Evaluation of the vitamin D and biomedical statuses of young children with β-thalassemia major at a single center in southern China Open
View article: Asymptomatic actinomycosis in a girl with thalassemia major
Asymptomatic actinomycosis in a girl with thalassemia major Open
We present a rare case of lung actinomycosis in a girl with thalassemia major with a competent immunological status. Chest computed tomography scans showed high intensity nodules in the right lower lung. Diagnosis was confirmed by revealin…
View article: An HIV-negative infant with systemic Talaromyces marneffei infection
An HIV-negative infant with systemic Talaromyces marneffei infection Open
A 2-year-old girl presented with fever for a week and lethargy for a day. Skin lesions were observed on both knees (Figure 1A). Human immunodeficiency virus (HIV) was tested seronegative. The concentration of total protein was at 746.8 mg/…