Uffe Bernchou
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View article: Optimising acute toxicity monitoring in prostate MR-guided radiotherapy workflow: Results from a prospective study using multiple electronic PRO assessments
Optimising acute toxicity monitoring in prostate MR-guided radiotherapy workflow: Results from a prospective study using multiple electronic PRO assessments Open
View article: Feasibility of a reduced gadolinium dose protocol for MRI-guided radiotherapy in glioblastoma
Feasibility of a reduced gadolinium dose protocol for MRI-guided radiotherapy in glioblastoma Open
Background and purpose: Magnetic resonance imaging-guided radiotherapy (MRIgRT) enables precise tumour targeting through adaptive planning, which is particularly relevant for glioblastoma due to its dynamic morphology. Gadolinium-based con…
View article: Liver Metastases Treated With Magnetic Resonance Imaging Guided Stereotactic Body Radiation Therapy: Outcomes of Tolerability, Acute Toxicity, and Quality of Life From the MOMENTUM Study
Liver Metastases Treated With Magnetic Resonance Imaging Guided Stereotactic Body Radiation Therapy: Outcomes of Tolerability, Acute Toxicity, and Quality of Life From the MOMENTUM Study Open
View article: An open-source nnU-net algorithm for automatic segmentation of MRI scans in the male pelvis for adaptive radiotherapy
An open-source nnU-net algorithm for automatic segmentation of MRI scans in the male pelvis for adaptive radiotherapy Open
Data related to the article: Front. Oncol. Sec. Radiation Oncology Volume 13 - 2023 | doi: 10.3389/fonc.2023.1285725 An open-source nnU-net algorithm for automatic segmentation of MRI scans in the male pelvis for adaptive radiotherapy Ebbe…
View article: Volume change of the prostate during moderately hypo-fractionated radiotherapy assessed by artificial intelligence
Volume change of the prostate during moderately hypo-fractionated radiotherapy assessed by artificial intelligence Open
Automated segmentation by our locally trained nnU-net was more consistent than manual delineations performed clinically. The population mean increase in prostate volume peaked at 110.8% by the 5th fraction after reduce over the remaining t…
View article: 1-year efficacy results after MR-guided risk-adapted stereotactic radiotherapy of infra-diaphragmatic oligometastases in a multicenter phase II trial
1-year efficacy results after MR-guided risk-adapted stereotactic radiotherapy of infra-diaphragmatic oligometastases in a multicenter phase II trial Open
In our study, treatment with risk-adapted, MR-guided SABR resulted in a high one-year local control and survival rate and could keep half of the patients off systemic therapy within the first year of follow-up.
View article: Feasibility and time gain of implementing artificial intelligence-based delineation tools in daily magnetic resonance image-guided adaptive prostate cancer radiotherapy
Feasibility and time gain of implementing artificial intelligence-based delineation tools in daily magnetic resonance image-guided adaptive prostate cancer radiotherapy Open
Implementing an AI-based workflow at the 1.5 T MRI-Linac is feasible and reduces the delineation time. Lower variance in delineation duration supports a better ability to plan daily treatment schedules and avoids delays.
View article: Impact of geometric correction on echo-planar imaging-based apparent diffusion coefficient maps for abdominal radiotherapy
Impact of geometric correction on echo-planar imaging-based apparent diffusion coefficient maps for abdominal radiotherapy Open
Objective . The apparent diffusion coefficient (ADC) extracted from diffusion-weighted magnetic resonance imaging (DWI) is a potential biomarker in radiotherapy (RT). DWI is often implemented with an echo-planar imaging (EPI) read-out due …
View article: Prediction of overall survival in patients with locally advanced pancreatic cancer using longitudinal diffusion-weighted MRI
Prediction of overall survival in patients with locally advanced pancreatic cancer using longitudinal diffusion-weighted MRI Open
Background and purpose Biomarkers for prediction of outcome in patients with pancreatic cancer are wanted in order to personalize the treatment. This study investigated the value of longitudinal diffusion-weighted magnetic resonance imagin…
View article: Adaptive MRI-guided stereotactic body radiation therapy for locally advanced pancreatic cancer – A phase II study
Adaptive MRI-guided stereotactic body radiation therapy for locally advanced pancreatic cancer – A phase II study Open
This study demonstrates that SBRT in patients with LAPC was associated with promising overall survival and resection rates. Furthermore, SBRT was safe and well tolerated, with limited severe toxicities.
View article: Treatment planning for MR-guided SBRT of pancreatic tumors on a 1.5 T MR-Linac: A global consensus protocol
Treatment planning for MR-guided SBRT of pancreatic tumors on a 1.5 T MR-Linac: A global consensus protocol Open
View article: A multi-institutional comparison of retrospective deformable dose accumulation for online adaptive magnetic resonance-guided radiotherapy
A multi-institutional comparison of retrospective deformable dose accumulation for online adaptive magnetic resonance-guided radiotherapy Open
View article: Contents
Contents Open
View article: Feasibility and Timegain of Implementing Ai-Assisted Delineation Tools in Daily Mri-Guided Adaptive Prostate Cancer Radiotherapy on a 1.5t Mri-Linac System: A Sequential Crossover Study
Feasibility and Timegain of Implementing Ai-Assisted Delineation Tools in Daily Mri-Guided Adaptive Prostate Cancer Radiotherapy on a 1.5t Mri-Linac System: A Sequential Crossover Study Open
View article: An open-source nnU-net algorithm for automatic segmentation of MRI scans in the male pelvis for adaptive radiotherapy
An open-source nnU-net algorithm for automatic segmentation of MRI scans in the male pelvis for adaptive radiotherapy Open
Background Adaptive MRI-guided radiotherapy (MRIgRT) requires accurate and efficient segmentation of organs and targets on MRI scans. Manual segmentation is time-consuming and variable, while deformable image registration (DIR)-based conto…
View article: An open-source nnU-net algorithm for automatic segmentation of MRI scans in the male pelvis for adaptive radiotherapy
An open-source nnU-net algorithm for automatic segmentation of MRI scans in the male pelvis for adaptive radiotherapy Open
Data related to the article: Front. Oncol. Sec. Radiation Oncology Volume 13 - 2023 | doi: 10.3389/fonc.2023.1285725 An open-source nnU-net algorithm for automatic segmentation of MRI scans in the male pelvis for adaptive radiotherapy Ebbe…
View article: Geometric distortions in clinical MRI sequences for radiotherapy: insights gained from a multicenter investigation
Geometric distortions in clinical MRI sequences for radiotherapy: insights gained from a multicenter investigation Open
There is a large variation in the geometric distortion levels of clinical MRI sequences across Danish RT centers, and between anatomical sites. The large variation observed makes harmonization of MRI sequences across institutions and adopt…
View article: Toward Global Consensus for MR-Guided Treatment Planning for Pancreatic Tumors on a 1.5 T MR-Linac
Toward Global Consensus for MR-Guided Treatment Planning for Pancreatic Tumors on a 1.5 T MR-Linac Open
View article: Impact of abdominal compression on intra-fractional motion and delivered dose in magnetic resonance image-guided adaptive radiation ablation of adrenal gland metastases
Impact of abdominal compression on intra-fractional motion and delivered dose in magnetic resonance image-guided adaptive radiation ablation of adrenal gland metastases Open
View article: Radiotherapy for Locally Advanced Pancreatic Adenocarcinoma—A Critical Review of Randomised Trials
Radiotherapy for Locally Advanced Pancreatic Adenocarcinoma—A Critical Review of Randomised Trials Open
Pancreatic cancer is rising as one of the leading causes of cancer-related death worldwide. Patients often present with advanced disease, limiting curative treatment options and therefore making management of the disease difficult. Systemi…
View article: Dose accumulation for MR-guided adaptive radiotherapy: From practical considerations to state-of-the-art clinical implementation
Dose accumulation for MR-guided adaptive radiotherapy: From practical considerations to state-of-the-art clinical implementation Open
MRI-linear accelerator (MR-linac) devices have been introduced into clinical practice in recent years and have enabled MR-guided adaptive radiation therapy (MRgART). However, by accounting for anatomical changes throughout radiation therap…
View article: The effect of respiration-induced target motion on 3D magnetic resonance images used to guide radiotherapy
The effect of respiration-induced target motion on 3D magnetic resonance images used to guide radiotherapy Open
View article: First multicentre experience of SABR for lymph node and liver oligometastatic disease on the unity MR-Linac
First multicentre experience of SABR for lymph node and liver oligometastatic disease on the unity MR-Linac Open
View article: Distributed learning optimisation of Cox models can leak patient data: Risks and solutions
Distributed learning optimisation of Cox models can leak patient data: Risks and solutions Open
Medical data are often highly sensitive, and frequently there are missing data. Due to the data's sensitive nature, there is an interest in creating modelling methods where the data are kept in each local centre to preserve their privacy, …
View article: Online adaptive radiotherapy potentially reduces toxicity for high-risk prostate cancer treatment
Online adaptive radiotherapy potentially reduces toxicity for high-risk prostate cancer treatment Open
View article: Feasibility, usability and acceptance of weekly electronic patient-reported outcomes among patients receiving pelvic CT- or online MR-guided radiotherapy – A prospective pilot study
Feasibility, usability and acceptance of weekly electronic patient-reported outcomes among patients receiving pelvic CT- or online MR-guided radiotherapy – A prospective pilot study Open
View article: Correction to: Development of patient-reported outcomes item set to evaluate acute treatment toxicity to pelvic online magnetic resonance-guided radiotherapy
Correction to: Development of patient-reported outcomes item set to evaluate acute treatment toxicity to pelvic online magnetic resonance-guided radiotherapy Open
View article: Development of patient-reported outcomes item set to evaluate acute treatment toxicity to pelvic online magnetic resonance-guided radiotherapy
Development of patient-reported outcomes item set to evaluate acute treatment toxicity to pelvic online magnetic resonance-guided radiotherapy Open
View article: Evolution of the gross tumour volume extent during radiotherapy for glioblastomas
Evolution of the gross tumour volume extent during radiotherapy for glioblastomas Open
View article: Accuracy of automatic structure propagation for daily magnetic resonance image-guided head and neck radiotherapy
Accuracy of automatic structure propagation for daily magnetic resonance image-guided head and neck radiotherapy Open
Deformable image registration (DIR) and contour propagation are used in daily online adaptation for hybrid MRI linac (MRL) treatments. The accuracy of the propagated contours may vary depending on the chosen workflow (WF), affecting the am…