Ujjawal Sharma
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View article: Sulforaphane: a natural organosulfur having potential to modulate apoptosis and survival signalling in cancer
Sulforaphane: a natural organosulfur having potential to modulate apoptosis and survival signalling in cancer Open
View article: Emerging nanotherapeutics for HPV-associated cancers: current advances, challenges, and future directions
Emerging nanotherapeutics for HPV-associated cancers: current advances, challenges, and future directions Open
View article: Epigenetic insights into prostate cancer: exploring histone modifications and their therapeutic implications
Epigenetic insights into prostate cancer: exploring histone modifications and their therapeutic implications Open
Prostate cancer is one of the most prevalent malignancies globally. This cancerous condition originates within the prostate gland, an integral part of the male reproductive system. The molecular mechanism underlying cancer is among the key…
View article: Role of emodin to prevent gastrointestinal cancers: recent trends and future prospective
Role of emodin to prevent gastrointestinal cancers: recent trends and future prospective Open
View article: Survey On Prevalence And Pharmacological Approaches In Non-Alcoholic Fatty Liver Disease And Steatohepatitis
Survey On Prevalence And Pharmacological Approaches In Non-Alcoholic Fatty Liver Disease And Steatohepatitis Open
Introduction: Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis have emerged as significant public health concerns, closely linked to metabolic syndrome. This study aimed to assess the prevalence, associated risk factors,…
View article: The heat of the battle: inflammation’s role in prostate cancer development and inflammation-targeted therapies
The heat of the battle: inflammation’s role in prostate cancer development and inflammation-targeted therapies Open
In prostate cancer (PC), chronic inflammation silently guides disease progression, playing a significant role. As a major global health concern, PC contributes to high mortality rates and rising new cases worldwide, highlighting the urgent…
View article: Mechanistic Insight of Pharmacological Aspects of Violacein: Recent Trends and Advancements
Mechanistic Insight of Pharmacological Aspects of Violacein: Recent Trends and Advancements Open
Since its discovery in the bacterium Chromobacterium violaceum , violacein—a striking purple pigment—has garnered significant interest due to its promising applications in the food and pharmaceutical industries. Violacein exhibits a range …
View article: Cost Effectiveness of Fruquintinib for Colorectal Cancer: A systematic review
Cost Effectiveness of Fruquintinib for Colorectal Cancer: A systematic review Open
Background: Colorectal cancer, one of the most prevalent cancers globally, originates from polyps in the colon or rectum, which can develop into cancer over time. It remains a leading cause of cancer-related deaths, imposing significant ec…
View article: Silymarin: a promising modulator of apoptosis and survival signaling in cancer
Silymarin: a promising modulator of apoptosis and survival signaling in cancer Open
View article: Harnessing Synergy in g‐C<sub>3</sub>N<sub>4</sub>/ZnO/PPy Nanocomposite for Efficient Photocatalytic Degradation of Phenolic and Antibiotic Pollutants
Harnessing Synergy in g‐C<sub>3</sub>N<sub>4</sub>/ZnO/PPy Nanocomposite for Efficient Photocatalytic Degradation of Phenolic and Antibiotic Pollutants Open
The study introduces an innovative Z‐scheme heterojunction g‐C 3 N 4 /ZnO/PPy (GZP) nanocomposite synthesized through a three‐step process: calcination, coprecipitation, and in situ polymerization of polypyrrole (PPy), with varied PPy conc…
View article: Oridonin: A natural terpenoid having the potential to modulate apoptosis and survival signaling in cancer
Oridonin: A natural terpenoid having the potential to modulate apoptosis and survival signaling in cancer Open
Background: Oridonin, a diterpenoid lactone derived from medicinal plants, has drawn considerable attention due to its therapeutic potential, particularly its anticancer properties. It demonstrates efficacy in inducing apoptosis, suppressi…
View article: Bisphenol A in Indian Take-Out Soups: Compliance, Implications and Sustainable Solutions
Bisphenol A in Indian Take-Out Soups: Compliance, Implications and Sustainable Solutions Open
This research investigates the migration of Bisphenol A (BPA) from packaging containers into take-out vegetable soups and premixed tomato soups through three replicate studies. The samples underwent extraction using solid-phase extraction …
View article: Ethyl Oleate, Hexadecenoic Acid, Phytol Profiling of Onosma bracteatum: Antibacterial, Anticancer and Molecular Docking Studies
Ethyl Oleate, Hexadecenoic Acid, Phytol Profiling of Onosma bracteatum: Antibacterial, Anticancer and Molecular Docking Studies Open
Research studies on phytochemicals and antibiotics utilizing extracts from medicinal plants have proliferated in the past few years. The phytochemicals profiling, antioxidant capacity, antibacterial properties, antiproliferative potential …
View article: A Comparative Review on Bisphenol A Sources, Environmental Levels, Migration, and Health Impacts in India and Global Context
A Comparative Review on Bisphenol A Sources, Environmental Levels, Migration, and Health Impacts in India and Global Context Open
Bisphenol A (BPA) is a widely utilized chemical found in numerous everyday products, including plastic containers, food packaging, and thermal paper. Research has linked BPA exposure to a range of health concerns, encompassing developmenta…
View article: Advancements and recent explorations of anti-cancer activity of chrysin: from molecular targets to therapeutic perspective
Advancements and recent explorations of anti-cancer activity of chrysin: from molecular targets to therapeutic perspective Open
In recent times, there have been notable advancements in comprehending the potential anti-cancer effects of chrysin (CH), a naturally occurring flavonoid compound found abundantly in various plant sources like honey, propolis, and certain …
View article: Melittin: a possible regulator of cancer proliferation in preclinical cell culture and animal models
Melittin: a possible regulator of cancer proliferation in preclinical cell culture and animal models Open
View article: Preparation of a Pt(II)–3-Hydroxy-2-tolyl-4<i>H</i>-chromen-4-one Complex Having Antimicrobial, Anticancerous, and Radical Scavenging Activities with Related Computational Studies
Preparation of a Pt(II)–3-Hydroxy-2-tolyl-4<i>H</i>-chromen-4-one Complex Having Antimicrobial, Anticancerous, and Radical Scavenging Activities with Related Computational Studies Open
A novel benzopyran-based platinum (II)-3-hydroxy-2-tolyl-4H-chromen-4-one (HToC) complex has been prepared and studied by UV-visible spectrophotometry. The study is based on the colored complexation between Pt(II) and HToC in the pH…
View article: Nutrition Survey and Protein Consumption Pattern in North Bengal
Nutrition Survey and Protein Consumption Pattern in North Bengal Open
This observational cross-sectional nutritional survey was done on 100 patients from the Hills and Dooars of North Bengal. The survey was done to study the contribution of protein, fat, and carbohydrate to the calorie intake of the populati…
View article: Dietary patterns and fertility status in men: Mediterranean diet does make a difference in ameliorating the rise in male infertility problems due to changing lifestyle
Dietary patterns and fertility status in men: Mediterranean diet does make a difference in ameliorating the rise in male infertility problems due to changing lifestyle Open
HIGHLIGHTS Infertility has been afflicting an increasing proportion of our society. Majority of the male infertility features are attributed to oligospermia. The present corresponding article highlights the salient predispose factors. One …
View article: Liposomal Nanoparticles: A Viable Nanoscale Drug Carriers for the Treatment of Cancer
Liposomal Nanoparticles: A Viable Nanoscale Drug Carriers for the Treatment of Cancer Open
Cancer immunotherapy is emerging as a promising therapeutic modality for achieving highly efficient therapeutic performance while avoiding tumor metastasis and relapse which are most common outcome of traditional cancer therapies (surgery,…
View article: <i>Withaferin</i> A: The Potent Anti-Cancer Agent from Ashwagandha
<i>Withaferin</i> A: The Potent Anti-Cancer Agent from Ashwagandha Open
View article: A novel analytical, bioanalytical and theoretical approach to the platinum(II)-3-hydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one complex
A novel analytical, bioanalytical and theoretical approach to the platinum(II)-3-hydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one complex Open
A concise, ingenious and expedite extractive spectrophotometric procedure for the micro-level analysis of Pt(II) using the novel synthesized Ligand of flavonoids family, 3-hydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one was elucidated by empl…
View article: Ferulic Acid: A Natural Phenol That Inhibits Neoplastic Events through Modulation of Oncogenic Signaling
Ferulic Acid: A Natural Phenol That Inhibits Neoplastic Events through Modulation of Oncogenic Signaling Open
Despite the immense therapeutic advances in the field of health sciences, cancer is still to be found among the global leading causes of morbidity and mortality. Ethnomedicinally, natural bioactive compounds isolated from various plant sou…
View article: Luteolin, a Potent Anticancer Compound: From Chemistry to Cellular Interactions and Synergetic Perspectives
Luteolin, a Potent Anticancer Compound: From Chemistry to Cellular Interactions and Synergetic Perspectives Open
Increasing rates of cancer incidence and the toxicity concerns of existing chemotherapeutic agents have intensified the research to explore more alternative routes to combat tumor. Luteolin, a flavone found in numerous fruits, vegetables, …
View article: Liposomes - Recent Advances, New Perspectives and Applications
Liposomes - Recent Advances, New Perspectives and Applications Open
The role of nanoscale drug carriers for the effective and controlled delivery of drugs and candidate antigens is instrumental in developing therapeutic and vaccine interventions for cancers, infectious diseases and beyond. As teachers of i…
View article: Mitophagy: An Emergence of New Player in Alzheimer’s Disease
Mitophagy: An Emergence of New Player in Alzheimer’s Disease Open
Mitochondria provide neurons not only energy as ATP to keep them growing, proliferating and developing, but they also control apoptosis. Due to their high bioenergetic demand, neurons which are highly specific terminally differentiated cel…
View article: Role of plant secondary metabolites as potential antimalarial drugs
Role of plant secondary metabolites as potential antimalarial drugs Open
Malaria is a global problem affecting a large population without any demarcation between developed and developing world communities. The already approved compounds for the treatment of the disease hold significant efficacy but the emergenc…
View article: Sporotrichosis: a Comprehensive Review on Recent Drug-Based Therapeutics and Management
Sporotrichosis: a Comprehensive Review on Recent Drug-Based Therapeutics and Management Open
View article: Mesenchymal stem cells in SARS-CoV-2 infection: A hype or hope
Mesenchymal stem cells in SARS-CoV-2 infection: A hype or hope Open
View article: SARS-CoV-2: Insights from the Immunopathogenesis and Current Clinical Diagnosis and Therapeutic Strategies
SARS-CoV-2: Insights from the Immunopathogenesis and Current Clinical Diagnosis and Therapeutic Strategies Open
The global public health scenario is worsening gradually as the confirmed cases of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infections are incessantly escalating with every passing day. The pathological condition caused…