Ujjwala Singh
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View article: Human leukocyte antigen epitope definition using site-directed mutagenesis
Human leukocyte antigen epitope definition using site-directed mutagenesis Open
View article: Site‐directed mutagenesis of <scp>HLA</scp> molecules reveals the functional epitope of a human <scp>HLA‐A1</scp>/<scp>A36</scp>‐specific monoclonal antibody
Site‐directed mutagenesis of <span>HLA</span> molecules reveals the functional epitope of a human <span>HLA‐A1</span>/<span>A36</span>‐specific monoclonal antibody Open
Eplet 44KM is currently listed in the HLA Epitope Registry but does not adhere to the eplet definition of an amino acid configuration within a 3.5 Å radius. Eplet 44KM has been previously redefined to the antibody‐verified reactivity patte…
View article: Role of miR-2392 in driving SARS-CoV-2 infection
Role of miR-2392 in driving SARS-CoV-2 infection Open
MicroRNAs (miRNAs) are small non-coding RNAs involved in post-transcriptional gene regulation that have a major impact on many diseases and provide an exciting avenue toward antiviral therapeutics. From patient transcriptomic data, we dete…
View article: Imaging findings in invasive rhino-orbito-cerebral mucormycosis in post–COVID-19 patients
Imaging findings in invasive rhino-orbito-cerebral mucormycosis in post–COVID-19 patients Open
Rhino-orbito-cerebral mucormycosis (ROCM) is a life-threatening addition to the COVID-19 disease spectrum and is caused by an angioinvasive saprophytic opportunistic fungus. Early diagnosis is important to avoid disease spread and mortalit…
View article: Lithium-Induced Hyperthyroidism in a Patient with Bipolar Type 1 Affective Disorder: A Rare Occurrence
Lithium-Induced Hyperthyroidism in a Patient with Bipolar Type 1 Affective Disorder: A Rare Occurrence Open
A 46-year-old female, previously diagnosed with bipolar affective disorder on lithium therapy, presented to us with manic symptoms. The blood investigations revealed elevated thyroxine and reduced thyroid-stimulating hormone with technetiu…
View article: Prevalence of Extended Spectrum Beta-lactamase and Carbapenemase Producers in Gram Negative Bacteria causing Blood Stream Infection in Intensive Care Unit Patients
Prevalence of Extended Spectrum Beta-lactamase and Carbapenemase Producers in Gram Negative Bacteria causing Blood Stream Infection in Intensive Care Unit Patients Open
Introduction: Blood Stream Infections (BSI) in Intensive Care Unit (ICU) patients at initial stages are acute infections which might even become life threatening. In developing countries, increasing antimicrobial resistance and emergence o…
View article: Castleman's Disease in an Adolescent
Castleman's Disease in an Adolescent Open
Castleman’s disease is a clinic-pathological entity of unknown etiology with non–neoplastic lymph node hyperplasia. It is extremely rare and can be found in patients of all age groups. It can present as localized with local signs and sympt…