Uma Sudhakar
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View article: Green Synthesis of Terminalia arjuna-mediated Zinc Oxide Nanogel for Enhanced Wound Healing—An In Vitro Study
Green Synthesis of Terminalia arjuna-mediated Zinc Oxide Nanogel for Enhanced Wound Healing—An In Vitro Study Open
View article: A Preliminary Clinicopathologic Study to Evaluate the Association of Human Papilloma Virus in Oral Squamous Cell Carcinoma and Its Influence on Prognostic Significance
A Preliminary Clinicopathologic Study to Evaluate the Association of Human Papilloma Virus in Oral Squamous Cell Carcinoma and Its Influence on Prognostic Significance Open
Background: In non-tobacco and non-alcohol users with oral cancer, oncogene viruses may play a significant role. Objective: To find the association of human papilloma virus (HPV) in oral squamous cell carcinomas (OSCC) and to find the infl…
View article: Evaluation of the immunohistochemical expression of oxidative DNA damage marker 8-OHdG in oral cancer
Evaluation of the immunohistochemical expression of oxidative DNA damage marker 8-OHdG in oral cancer Open
Objective: The present immunohistochemical investigation attempted to evaluate the concentrations of 8-hydroxy-2-deoxyguanosine (8-OHdG) as a prospective DNA damage biomarker in primary oral squamous cell carcinoma (OSCC) patients compared…
View article: Comparative drug release kinetics of Terminalia arjuna mediated SeNPs NanoGel and ZnONPs NanoGel – An in-vitro study
Comparative drug release kinetics of Terminalia arjuna mediated SeNPs NanoGel and ZnONPs NanoGel – An in-vitro study Open
Terminalia arjuna mediated SeNPs gel shows promise for more rapid and sustained drug delivery in the management of chronic periodontitis through local drug delivery systems.
View article: Terminalia arjuna: An overview of its magical properties
Terminalia arjuna: An overview of its magical properties Open
Terminalia arjuna, native to the Indian subcontinent, is renowned for its cardioprotective benefits, owing to bioactive compounds like antioxidants and anti-inflammatory agents. Beyond heart health, it is gaining attention for applications…
View article: Expression of mTOR, CD163, α-SMA, FOXp3 as survival predictors and its significance in patients with oral squamous cell carcinoma
Expression of mTOR, CD163, α-SMA, FOXp3 as survival predictors and its significance in patients with oral squamous cell carcinoma Open
The study reveals that over expression of CD163 and α-SMA is strongly associated with disease outcome. The combinations of all the four marker expression profile will be emerging strategy towards prognosis and also to determine survival ou…
View article: Comparative analysis of antimicrobial efficacy and cytotoxicity of Terminalia arjuna bark extract mediated zinc oxide nanoparticles (ZnONPs) and selenium nanoparticles (SeNPs): An in-vitro study
Comparative analysis of antimicrobial efficacy and cytotoxicity of Terminalia arjuna bark extract mediated zinc oxide nanoparticles (ZnONPs) and selenium nanoparticles (SeNPs): An in-vitro study Open
This study provides an in-depth comparative analysis of the antimicrobial efficacy and cytotoxic effects of -mediated Selenium Nanoparticles (TA-SeNPs) and Zinc Oxide Nanoparticles (TA-ZnONPs) in the context of chronic periodontitis. The w…
View article: Evaluation of Healing Efficacy of Collagen Matrix and Connective Tissue Graft for Root Coverage Using Doppler Flowmetry: A Case Report
Evaluation of Healing Efficacy of Collagen Matrix and Connective Tissue Graft for Root Coverage Using Doppler Flowmetry: A Case Report Open
View article: Anti-oxidant, anti-inflammatory and antimicrobial activity of aqueous extract from acerola and amla
Anti-oxidant, anti-inflammatory and antimicrobial activity of aqueous extract from acerola and amla Open
Amla, scientifically known as emblica officinalis and Acerola (malphigian emarginata) both are Vitamin C fruits possess varied medicinal properties being used for preventive disease health management strategies. Therefore, it is of interes…
View article: Comparative Evaluation of Antioxidative and Anti-inflammatory Properties of Acerola-Mediated Silver Nanogel and Copper Oxide Nanogel
Comparative Evaluation of Antioxidative and Anti-inflammatory Properties of Acerola-Mediated Silver Nanogel and Copper Oxide Nanogel Open
The present study revealed that both nanoparticles provided better antioxidant and anti-inflammatory activities. This study also elaborates on the pharmacological potential of both nanoparticles, which could be further explored for applica…
View article: Evaluation of Knowledge, Attitude, and Practice Regarding Positron Emission Tomography in Head and Neck Cancers among Oral Physicians in South India: A Cross- Sectional Study
Evaluation of Knowledge, Attitude, and Practice Regarding Positron Emission Tomography in Head and Neck Cancers among Oral Physicians in South India: A Cross- Sectional Study Open
Background: Positron emission tomography (PET) when combined with computed tomography (CT) offers an accurate extent of disease and provides additional information regarding nodal and distant metastases. Aim: To evaluate the knowledge, att…
View article: Gingival tissue evaluation using soft tissue-cone-beam computed tomography and root coverage esthetic score in the treatment of isolated gingival recession: A clinical study
Gingival tissue evaluation using soft tissue-cone-beam computed tomography and root coverage esthetic score in the treatment of isolated gingival recession: A clinical study Open
Objectives: Comparative assessment of the effectiveness of coronally advanced flap (CAF) with subepithelial connective tissue graft (SCTG) and the envelope technique with SCTG in Miller’s Class I recession utilizing soft tissue-cone-beam c…
View article: Comparative Evaluation of L-PRF and Ofloxacin Incorporated L-PRF as an Adjunctive to SRP-A Split-Mouth Randomized Clinical Trial
Comparative Evaluation of L-PRF and Ofloxacin Incorporated L-PRF as an Adjunctive to SRP-A Split-Mouth Randomized Clinical Trial Open
A BSTRACT Aim and Objectives: To compare and evaluate the clinical efficacy of “ofloxacin incorporated L-PRF” and “L-PRF alone” when used as an adjuvant to non-surgical periodontal therapy. Materials and Methods: A split-mouth study was co…
View article: Comparative Evaluation of Degradation Properties of Leukocyte-platelet Rich Fibrin and Advanced Platelet Rich Fibrin+: A Microbiological In Vitro Study
Comparative Evaluation of Degradation Properties of Leukocyte-platelet Rich Fibrin and Advanced Platelet Rich Fibrin+: A Microbiological In Vitro Study Open
View article: Expression dynamics of microRNA-223/Ras-associated binding protein 12 axis in Stage III/Grade B periodontal disease: A case–control analysis
Expression dynamics of microRNA-223/Ras-associated binding protein 12 axis in Stage III/Grade B periodontal disease: A case–control analysis Open
Background: The intricate interplay between periodontal polymicrobial flora and an altered immune response is the central cause of periodontal disease. Multiple cell death methods and their interactions, along with the associated signaling…
View article: Association Between Periodontal Health And Obesity
Association Between Periodontal Health And Obesity Open
This comprehensive review examines the intricate association between obesity and periodontal health. Over the years, research has unveiled a strong correlation between these two seemingly distinct health concerns. Obesity, characterized by…
View article: MicroRNA-221-5p, MicroRNA-222-5p, and MicroRNA-223-5p Expression Patterns in Association with the Pathogenesis of Periodontal Disease: A Case–Control Analysis
MicroRNA-221-5p, MicroRNA-222-5p, and MicroRNA-223-5p Expression Patterns in Association with the Pathogenesis of Periodontal Disease: A Case–Control Analysis Open
MicroRNAs (miRs) could possess a significant role during periodontal tissue development, homeostasis, and degradation of periodontal tissue integrity due to periodontal disease. 5In addition, they have been suggested as essential contribut…
View article: Evaluation of Salivary Galectin-3 Level and its Potential Role in Increasing the Severity of COVID-19 Infection in Patients with Periodontitis
Evaluation of Salivary Galectin-3 Level and its Potential Role in Increasing the Severity of COVID-19 Infection in Patients with Periodontitis Open
virus with the periodontal tissues, because of high expression of angiotensin-converting enzyme 2 (ACE2), CD147, transmembrane serine protease 2 (TMPRSS2), and furin which are expressed in oral epithelial cells. 8,9The proteases produced b…
View article: Phytochemical Analysis and in vitro Cell Viability Effects of Ethanolic Extract of Ormocarpum cochinchinense on Mouse Embryonic Fibroblasts
Phytochemical Analysis and in vitro Cell Viability Effects of Ethanolic Extract of Ormocarpum cochinchinense on Mouse Embryonic Fibroblasts Open
Background: Ormocarpum cochinchinense is a medicinal herb known to be used by traditional bone setters for the healing of bone fractures. This herb has many active biomolecules, which are responsible for biological activities like antioxid…
View article: Effects of Non-surgical Periodontal Therapy on Saliva and Gingival Crevicular Fluid Levels of Chemerin in Periodontitis Subjects With and Without Type 2 Diabetes Mellitus
Effects of Non-surgical Periodontal Therapy on Saliva and Gingival Crevicular Fluid Levels of Chemerin in Periodontitis Subjects With and Without Type 2 Diabetes Mellitus Open
Background Evidence had shown a bi-directional link between diabetes mellitus and periodontitis. Chemerin, an adipose tissue-specific adipokine plays a significant role in adipocyte initiation and differentiation that directly influences g…
View article: Extracellular microRNA-223-5p Levels in Plasma, Saliva, and Gingival Crevicular Fluid in Periodontal Disease as a Potential Diagnostic Marker − A Case–Control Analysis
Extracellular microRNA-223-5p Levels in Plasma, Saliva, and Gingival Crevicular Fluid in Periodontal Disease as a Potential Diagnostic Marker − A Case–Control Analysis Open
Introduction: Periodontal disease is distinguished by an aberrant host response to oral pathogens, leading to soft and hard tooth-supporting tissue inflammation. MicroRNAs are minute, single-stranded, highly dynamic biomolecules that contr…
View article: Association Between Periodontal Health and Systemic Health: A Review Article
Association Between Periodontal Health and Systemic Health: A Review Article Open
Most current studies recommends that periodontal diseases correlated with systemic diseases which includes cardiovascular disorders, respiratory diseases, pregnancy, endocrine diseases, musculoskeletal system, nervous system, renal system …
View article: Assessment of the anti-oxidant reduced glutathione in oral squamous cell carcinoma – Systematic review and meta-analysis
Assessment of the anti-oxidant reduced glutathione in oral squamous cell carcinoma – Systematic review and meta-analysis Open
Background: The excess reactive oxygen species or free radicals reaction leads to oxidative injury to the biological components such as cells and tissues, which would result in the initiation and progression of carcinogenesis. The magnitud…
View article: Collocation of Malondialdehyde and Superoxide Dismutase Levels in Chronic Periodontitis and Pruning them Post-scaling and Root Planing Coupled with Vitamin E Supplementation
Collocation of Malondialdehyde and Superoxide Dismutase Levels in Chronic Periodontitis and Pruning them Post-scaling and Root Planing Coupled with Vitamin E Supplementation Open
Halliwell's postulates, those being the criteria required to be fulfilled before ROS can be concluded to be key mediators of tissue injury. 4ipid peroxidation (LPO) is one of the major outcomes of ROS-induced tissue damage.When ROS interac…
View article: Concentrated growth factors in the treatment of adjacent multiple gingival recessions: A split-mouth randomized control trial
Concentrated growth factors in the treatment of adjacent multiple gingival recessions: A split-mouth randomized control trial Open
: The aim of this study was to determine the clinical effect of Concentrated Growth Factor (CGF) in combination with Coronally Advanced Flap (CAF) compared to CAF alone in the treatment of adjacent multiple Miller’s Class I GRs. A total of…
View article: A minimally invasive surgical approach for treatment of ankyloglossia (Tounge Tie) with diode laser: A case report (A developmental anomaly)
A minimally invasive surgical approach for treatment of ankyloglossia (Tounge Tie) with diode laser: A case report (A developmental anomaly) Open
Tongue tie otherwise called as Ankyloglossia is a developmental anomaly commonly characterized by a very short lingual frenulum that literally restricts the movements of tongue from the floor of mouth. An uncommon thick band extending bene…
View article: In-vitro Antioxidant and In-vitro Anti-inflammatory activities of Ethanolic leaves extract of Ormocarpum Cochinchinense
In-vitro Antioxidant and In-vitro Anti-inflammatory activities of Ethanolic leaves extract of Ormocarpum Cochinchinense Open
Introduction: Periodontitis, a chronic inflammatory disease with microbial etiology, is mediated by multiple inflammatory processes and oxidative stress is now well recognized as a part of periodontal pathogenesis. A balance between reacti…
View article: Malondialdehyde, an Oxidative Stress Marker in Oral Squamous Cell Carcinoma—A Systematic Review and Meta-Analysis
Malondialdehyde, an Oxidative Stress Marker in Oral Squamous Cell Carcinoma—A Systematic Review and Meta-Analysis Open
Objective: To qualitative and quantitatively review published literature assessing the oxidative stress marker malondialdehyde (MDA) in oral squamous cell carcinoma (OSCC). Methodology: Pubmed (MeSH), Science Direct, Scopus, Web of Science…
View article: Resistin levels in the gingival crevicular fluid among diabetic and non-diabetic chronic periodontitis patients.
Resistin levels in the gingival crevicular fluid among diabetic and non-diabetic chronic periodontitis patients. Open
It is of interest to document theresistin levels in chronic periodontitis patients (CP) with or without type 2 diabetes mellitus (T2DM) in the gingival crevicular fluid (GCF).The expression of resistin was significantly higher in chronic p…
View article: Azhitromycin and periodontal disease: Effect on clinical parameters, P.gingivalis and reactive oxygen species
Azhitromycin and periodontal disease: Effect on clinical parameters, P.gingivalis and reactive oxygen species Open
The current study was aimed at estimating the effect of azithromycin as an adjunct on clinical parameters, microbiological and biochemical parameters in chronic periodontitis subjects. Clinical parameters,namely gingival index, papillary b…