Muhammad Ashraf
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View article: Formulation of pH responsive polymeric hydrogels for prolonged delivery of famciclovir with biosafety evaluation
Formulation of pH responsive polymeric hydrogels for prolonged delivery of famciclovir with biosafety evaluation Open
Recent study aimed to fabricate pH responsive, intelligent, Pluronic F127 based polymeric system for controlled delivery of Famciclovir. Nine formulations were developed through free radical polymerization. Polymeric system exhibited pH de…
View article: Cell Culture Media and Raman Spectra Preprocessing Procedures Impact Glucose Chemometrics
Cell Culture Media and Raman Spectra Preprocessing Procedures Impact Glucose Chemometrics Open
Deployment of process analytical technology tools such as Raman or IR spectroscopy and associated multivariate calibration models for process monitoring and control plays an important role in process automation and advanced manufacturing o…
View article: Plastic footprint deteriorates dryland carbon footprint across soil–plant-atmosphere continuum
Plastic footprint deteriorates dryland carbon footprint across soil–plant-atmosphere continuum Open
Plastic fragments are widely found in the soil profile of terrestrial ecosystems, forming plastic footprint and posing increasing threat to soil functionality and carbon (C) footprint. It is unclear how plastic footprint affects C cycling,…
View article: Benefits of mint for the improvement of health based on its usage in pharmaceutical and food industry
Benefits of mint for the improvement of health based on its usage in pharmaceutical and food industry Open
Aromatic herbs' market values have risen because of rise in food, biotechnology, medicines and cosmetics.Mentha piperita L. is famous for its therapeutic properties whose health advantages are well recognized by the pharmaceutical and food…
View article: Formulation and Characterization of Polymeric Cross-Linked Hydrogel Patches for Topical Delivery of Antibiotic for Healing Wound Infections
Formulation and Characterization of Polymeric Cross-Linked Hydrogel Patches for Topical Delivery of Antibiotic for Healing Wound Infections Open
Wound healing faces significant challenges in clinical settings. It often contains a series of dynamic and complex physiological healing processes. Instead of creams, ointments and solutions, alternative treatment approaches are needed. Th…
View article: Fabrication of Stimuli-Responsive Quince/Mucin Co-Poly (Methacrylate) Hydrogel Matrices for the Controlled Delivery of Acyclovir Sodium: Design, Characterization and Toxicity Evaluation
Fabrication of Stimuli-Responsive Quince/Mucin Co-Poly (Methacrylate) Hydrogel Matrices for the Controlled Delivery of Acyclovir Sodium: Design, Characterization and Toxicity Evaluation Open
Free-radical polymerization technique was adopted to fabricate a stimuli-responsive intelligent quince/mucin co-poly (methacrylate) hydrogel for the controlled delivery of acyclovir sodium. The developed hydrogel matrices were appraised us…
View article: pH-Responsive, Hemocompatible, and Non-Toxic Polysaccharide-Based Hydrogel from Seeds of Salvia spinosa L. for Sustained Release of Febuxostat
pH-Responsive, Hemocompatible, and Non-Toxic Polysaccharide-Based Hydrogel from Seeds of Salvia spinosa L. for Sustained Release of Febuxostat Open
Herein, a polysaccharide-based hydrogel from seeds of Salvia spinosa (SSH) was evaluated as a pH-responsive, superporous, hemocompatible, non-toxic, and sustained release material. The SSH-based tablets showed pH-dependent swelling (pH 7.4…
View article: Preparation and characterization of polymeric cross-linked hydrogel patch for topical delivery of gentamicin
Preparation and characterization of polymeric cross-linked hydrogel patch for topical delivery of gentamicin Open
This research aimed to prepare and characterize a new type of polymeric cross-linked topical hydrogel patches for the treatment of wound infections. The free radical polymerization method was used to prepare the topical hydrogel patches by…
View article: Microscopic Analysis of Particulates in Pharmaceutical Products: A Case Study
Microscopic Analysis of Particulates in Pharmaceutical Products: A Case Study Open
Journal Article Microscopic Analysis of Particulates in Pharmaceutical Products: A Case Study Get access Youlong Ma, Youlong Ma Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Quality, Center …
View article: Feasibility of Enhancing Skin Permeability of Acyclovir through Sterile Topical Lyophilized Wafer on Self-Dissolving Microneedle-Treated Skin
Feasibility of Enhancing Skin Permeability of Acyclovir through Sterile Topical Lyophilized Wafer on Self-Dissolving Microneedle-Treated Skin Open
Acyclovir is an antiviral drug that is frequently prescribed for the herpes virus. However, the drug requires frequent dosing due to limited bioavailability (10–26.7%). The rationale of the present study was to develop a self-dissolving mi…
View article: An advanced automation platform coupled with mass spectrometry for investigating <i>in vitro</i> human skin permeation of UV filters and excipients in sunscreen products
An advanced automation platform coupled with mass spectrometry for investigating <i>in vitro</i> human skin permeation of UV filters and excipients in sunscreen products Open
Rationale Systemic absorption of UV‐filtering chemicals following topical application of sunscreens may present a safety concern. The Food and Drug Administration (FDA) had recommended an in vitro skin permeation test (IVPT) to evaluate th…
View article: EVALUATING THE PHYTOTOXIC EFFECTS OF SOME PLANT SPECIES OF SEMI-ARID REGIONS
EVALUATING THE PHYTOTOXIC EFFECTS OF SOME PLANT SPECIES OF SEMI-ARID REGIONS Open
The most effective method for weed control is the use of herbicides. However, the scope of this method is narrowing down due to herbicide-resistant weeds and the non-availability of new chemistry herbicides. Hence, to explore natural weed …
View article: Acute toxicity study of a polysaccharide based hydrogel from linseed for potential use in drug delivery system
Acute toxicity study of a polysaccharide based hydrogel from linseed for potential use in drug delivery system Open
Linseed hydrogel (LSH) was evaluated by acute toxicity for its potential application in oral drug delivery design. White albino mice and rabbits were divided in four groups (I-IV) and different doses of LSH (1, 2 and 5 g/kg body weight) we…
View article: Significance of Cryogenic Broad Ion Beam Milling in Evaluating Microstructures of PLGA-based Drug Products
Significance of Cryogenic Broad Ion Beam Milling in Evaluating Microstructures of PLGA-based Drug Products Open
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