Umesh Kumar Patil
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View article: Potential of apitherapy in the management of cardiovascular diseases
Potential of apitherapy in the management of cardiovascular diseases Open
Apitherapy has been used as an adjunctive medical practice in several countries, and bee products or apitherapeutic agents are being consistently utilized for millennia by humanity to treat and prevent an assortment of illnesses. This revi…
View article: Cognitive enhancing effect of an extract of Swertia chirata against memory impairment induced by aluminum chloride
Cognitive enhancing effect of an extract of Swertia chirata against memory impairment induced by aluminum chloride Open
Background: The most advanced type of neurodegenerative disease, Alzheimer's disease (AD), significantly reduces cognitive performance. Oxidative stress plays a role in the pathophysiological pathways of several neurodegenerative illnesses…
View article: Analysis of Students’ Digital Literacy Skills and Attitude Towards Drug-Related Information Resources
Analysis of Students’ Digital Literacy Skills and Attitude Towards Drug-Related Information Resources Open
The research examined pharmacy students’ digital literacy skills and attitudes toward drug-related information resources. A self-administered online questionnaire created with Google Forms was used to assess these aspects. The researchers …
View article: Medicinal and culinary importance of edible flowers of indian origin: an in-depth review
Medicinal and culinary importance of edible flowers of indian origin: an in-depth review Open
This comprehensive examination delves into the multifaceted characteristics of edible flowers, underlining their significance as sources of natural ingredients and their medicinal properties. The review commences with an introductory secti…
View article: Evaluating Digital Competency among Pharmacy Students: A Study of Selected Pharmacy Institutes in India
Evaluating Digital Competency among Pharmacy Students: A Study of Selected Pharmacy Institutes in India Open
This study investigated digital competence among pharmacy students. A survey of 1430 pharmacy students across 25 institutes in India revealed broad agreement on the importance of digital literacy, but with challenges varying on student dem…
View article: One Pot Synthesis of Alkyl Nitriles
One Pot Synthesis of Alkyl Nitriles Open
A one-pot synthesis method to produce alkyl nitriles using the corresponding aliphatic carboxylic acid has been developed. The process involves treating the aliphatic acid with thionyl chloride to obtain the corresponding aliphatic acid ch…
View article: Tetra Butyl Ammonium Bromide Catalyzed Synthesis of Thiols and Thioethers
Tetra Butyl Ammonium Bromide Catalyzed Synthesis of Thiols and Thioethers Open
A simple and commercially feasible route of synthesis of thiols and thioethers was developed using a simple phase transfer catalyst, i.e., Tetra Butyl Ammonium Bromide (TBAB). Sodium hydrogen sulfide (NaSH) is used as a sulfurization agent…
View article: An insight into pharmaceutical challenges with ionic liquids: where do we stand in transdermal delivery?
An insight into pharmaceutical challenges with ionic liquids: where do we stand in transdermal delivery? Open
Ionic liquids (ILs) represent an exciting and promising solution for advancing drug delivery platforms. Their unique properties, including broad chemical diversity, adaptable structures, and exceptional thermal stability, make them ideal c…
View article: Combinatorial Delivery of Docetaxel- and Erlotinib-Loaded Functionalized Nanostructured Lipid Carriers for the Treatment of Triple-Negative Breast Cancer Using Quality-by-Design Approach
Combinatorial Delivery of Docetaxel- and Erlotinib-Loaded Functionalized Nanostructured Lipid Carriers for the Treatment of Triple-Negative Breast Cancer Using Quality-by-Design Approach Open
This study explored the combined administration of docetaxel (DOC) and erlotinib (ERL) using nanostructured lipid carriers (NLCs), with folic acid (FA) conjugation to enhance their synergistic anticancer efficacy against triple-negative br…
View article: Development of stability indicating RP-HPLC method for Quercetin estimation in Nanostructure liquid crystalline dispersion
Development of stability indicating RP-HPLC method for Quercetin estimation in Nanostructure liquid crystalline dispersion Open
An attempt has been made to develop stability representing the reverse-phase High-Performance Liquid Chromatography (RP-HPLC) method for quantitative estimation of quercetin Nanostructure liquid crystalline dispersion. HPLC method was deve…
View article: Editorial: Stimuli-responsive lipid-bioactive conjugate-based nanocarriers: a smart approach in biomaterial applications
Editorial: Stimuli-responsive lipid-bioactive conjugate-based nanocarriers: a smart approach in biomaterial applications Open
EDITORIAL article Front. Bioeng. Biotechnol., 30 May 2024Sec. Biomaterials Volume 12 - 2024 | https://doi.org/10.3389/fbioe.2024.1431458
View article: A comprehensive review on the molecular mechanism of Ginkgo biloba Linn. activity in various metabolic syndromes
A comprehensive review on the molecular mechanism of Ginkgo biloba Linn. activity in various metabolic syndromes Open
Introduction: In this communication the focus is on the summarization of the complex molecular pathways that Ginkgo biloba Linn. utilizes to treat metabolic syndromes, a major international health concern marked by interrelated risk factor…
View article: Molecular Docking Studies on Phytoconstituent Isolated from Nyctanthes arbortristis Linn.
Molecular Docking Studies on Phytoconstituent Isolated from Nyctanthes arbortristis Linn. Open
Background Nyctanthes arbortristis Linn., popularly referred to as Parijat or Night-flowering Jasmine, has garnered significant attention in traditional medicinal practices owing to its wide-ranging array of phytochemical constituents. The…
View article: Exploring the Potential of Dietary Phytochemicals in Cancer Prevention: A Comprehensive Review
Exploring the Potential of Dietary Phytochemicals in Cancer Prevention: A Comprehensive Review Open
Cancer is a significant global health issue and a primary cause of death. Extensive research has led to the development of various anticancer medications, driven by an improved knowledge and comprehension of the molecular pathways involved…
View article: Antihyperlipidemic Bioactivity Guided Isolation and Structural Elucidation of Isolated Phytoconstituents from Convolvulus pluricaulis Choisy
Antihyperlipidemic Bioactivity Guided Isolation and Structural Elucidation of Isolated Phytoconstituents from Convolvulus pluricaulis Choisy Open
Background: Atherosclerosis is a crucial element in the origination of coronary heart disease (CHD). Lipid aggregation inside the coronary arteries walls lead to the occurrence of hyperlipidemia. Aim: The research was conducted for assessi…
View article: Potentials of plant derived products for the treatment of skin disorders
Potentials of plant derived products for the treatment of skin disorders Open
The skin is the body's largest organ. The epidermis and dermis make up the skin, and their primary purpose is to defend the body from adverse environmental factors like chemicals, allergens, toxins, and bacteria. Many different types of na…
View article: A Cross-sectional Study to Assess Pandu Vyadhi (Anemia) with Special Reference to RBC Indices and Morphology: A Study Protocol
A Cross-sectional Study to Assess Pandu Vyadhi (Anemia) with Special Reference to RBC Indices and Morphology: A Study Protocol Open
Background: Ayurveda is a science of life & its holistic approach towards Dietary habits, seasonal regimes, daily regimes, lifestyle practices helps to maintain health of an individual. Inadequate dietary intake or lack of balanced diet le…
View article: Palliative Action of Woodfordia fruticosa Leaves Containing Woodfruticosin on Biological Redox Imbalance and Anemia in CFA–Induced Arthritic Rats
Palliative Action of Woodfordia fruticosa Leaves Containing Woodfruticosin on Biological Redox Imbalance and Anemia in CFA–Induced Arthritic Rats Open
Background: Rheumatoid Arthritis (RA) is a chronic disorder affecting musculoskeletal and autoimmune system with inflammatory characteristics. Anemia is most prevailing, among other extra-articular complications in RA. These complications …
View article: GC-MS Analysis and Antiproliferative Effect of Ethanolic Extract of Apium graveolens L. seeds on MCF-7 Human Breast Cancer Cell Lines
GC-MS Analysis and Antiproliferative Effect of Ethanolic Extract of Apium graveolens L. seeds on MCF-7 Human Breast Cancer Cell Lines Open
Objectives: The aim of this study was to identify main phytocompounds and to evaluate the antiproliferative effect of the ethanolic extract of Apium graveolens seeds. Materials and Methods: in vitro antiproliferative study of A. graveolens…
View article: CCDC 2237300: Experimental Crystal Structure Determination
CCDC 2237300: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Development and validation of a simple stability-indicating HPLC method for the quantitation of berberine in pharmaceuticals, ayurvedic, homeopathic products and novel nanoformulation
Development and validation of a simple stability-indicating HPLC method for the quantitation of berberine in pharmaceuticals, ayurvedic, homeopathic products and novel nanoformulation Open
Berberine has been shown to have therapeutic advantages in the management of different diseases. Due to its actions and therapeutic applications, in compliance with “The International Council for Harmonisation of Technical Requirements for…
View article: Delayed Release HPMC Capsules for Efficient Delivery of Cholecalciferol Solid Dispersion
Delayed Release HPMC Capsules for Efficient Delivery of Cholecalciferol Solid Dispersion Open
Introduction: The deficiency of Vitamin D is associated with an increased risk of various diseases and deficiency of this Vitamin is recognized in individuals all over the world. Therefore, the intake of Vitamin D has become essential. Obj…
View article: Development and Validation of a Simple Stability-Indicating HPLC Method for the Quantitation of Acyclovir in Pharma-ceuticals and Novel Nanoformulation
Development and Validation of a Simple Stability-Indicating HPLC Method for the Quantitation of Acyclovir in Pharma-ceuticals and Novel Nanoformulation Open
Acyclovir has been shown to have therapeutic advantages in the management of different viral diseases. Owing to its tremendous and attractive therapeutic applications, a quick, precise, and specific HPLC method was developed and validated …
View article: Novel Process for Preparation of Oxazolonone, Benzoxazolonone
Novel Process for Preparation of Oxazolonone, Benzoxazolonone Open
Synthesis of oxazolonone, benzoxazolononeby using amino hydroxy compound, alkyl haloformate, trialkylamine and DMF as solvents. Herein used simple carbonylation agent such as alkylhaloformate instead of phosgene and Triphosgene. Developed …