Umesh K. Reddy
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View article: Deciphering the genetic basis of chlorophyll fluorescence parameters and vegetation indices under heat stress in blueberry
Deciphering the genetic basis of chlorophyll fluorescence parameters and vegetation indices under heat stress in blueberry Open
This study provides a deeper understanding of the genetic basis of chlorophyll fluorescence under heat stress in blueberries, offering valuable information for breeding strategies to develop blueberry cultivars with enhanced photosynthetic…
View article: Integrated multilayer regulatory networks for arsenic (As) stress resilience in plants
Integrated multilayer regulatory networks for arsenic (As) stress resilience in plants Open
Arsenic (As) toxicity severely impacts plant health, agricultural productivity, and food security. In response to stress, plants deploy intricate regulatory mechanisms that coordinate gene expression and defense strategies. Considerable pr…
View article: Uncovering the genetic architecture of pungency, carotenoids, and flavor in <i>Capsicum chinense</i> via TWAS-mGWAS integration and spatial Transcriptomics
Uncovering the genetic architecture of pungency, carotenoids, and flavor in <i>Capsicum chinense</i> via TWAS-mGWAS integration and spatial Transcriptomics Open
Capsicum chinense (habanero pepper) exhibits substantial variation in fruit pungency, color, and flavor due to its rich secondary metabolite composition, including capsaicinoids, carotenoids, and volatile organic compounds (VOCs). To disse…
View article: Generation and characterization of novel transcriptome-derived SSR markers for genetic applications in blueberry
Generation and characterization of novel transcriptome-derived SSR markers for genetic applications in blueberry Open
Blueberries (Vaccinium spp.) are small fruit crops native to North America but grown commercially in several countries. There has been a steady increase in consumer demand for blueberries, owing to their numerous health benefits attributab…
View article: Capsaicin as a Microbiome Modulator: Metabolic Interactions and Implications for Host Health
Capsaicin as a Microbiome Modulator: Metabolic Interactions and Implications for Host Health Open
Background/Objectives: Capsaicin is the principal pungent compound in chili peppers and is increasingly recognized as a multifunctional phytochemical with systemic effects beyond its sensory properties. It has been linked to metabolic regu…
View article: Cucurbitacin Profile and Metalloid Stress Response in <scp><i>Cucurbita pepo</i></scp> L. Upon Arsenic Exposure
Cucurbitacin Profile and Metalloid Stress Response in <span><i>Cucurbita pepo</i></span> L. Upon Arsenic Exposure Open
Cucurbits are cultivated worldwide in regions with high concentrations of arsenic (As), a hazardous metalloid, affecting produce quality and increasing the consumer exposure. Cucurbitacins are herbivore‐deterrent secondary metabolites that…
View article: Root proteomics revealed a shift in pathways in response to varying NaCl levels, as an adaptability to salt stress in Pistachio rootstock UCB-1
Root proteomics revealed a shift in pathways in response to varying NaCl levels, as an adaptability to salt stress in Pistachio rootstock UCB-1 Open
View article: Curcumin-Induced Molecular Mechanisms in U-87 MG Glioblastoma Cells: Insights from Global Gene Expression Profiling
Curcumin-Induced Molecular Mechanisms in U-87 MG Glioblastoma Cells: Insights from Global Gene Expression Profiling Open
Curcumin, a major phytochemical derived from Curcuma longa, has been shown to enhance the efficacy of chemotherapeutic agents such as doxorubicin, 5-fluorouracil, and cisplatin by overcoming drug resistance, making it a promising adjunct i…
View article: Curcumin-Induced Molecular Mechanisms in U-87 MG Glioblastoma Cells: Insights from Global Gene Expression Profiling
Curcumin-Induced Molecular Mechanisms in U-87 MG Glioblastoma Cells: Insights from Global Gene Expression Profiling Open
Curcumin, a major phytochemical derived from Curcuma longa, has been shown to enhance the efficacy of chemotherapeutic agents such as doxorubicin, 5-fluorouracil, and cisplatin by overcoming drug resistance, making it a promising adjunct i…
View article: Exploring the multifaceted dynamics of flowering time regulation in field crops: Insight and intervention approaches
Exploring the multifaceted dynamics of flowering time regulation in field crops: Insight and intervention approaches Open
The flowering time (FTi) plays a critical role in the reproductive success and yield of various crop species by directly impacting both the quality and quantity of grain yield. Achieving optimal FTi is crucial for maximizing reproductive s…
View article: Global Gene Expression Profiling Reveals Curcumin-Induced Molecular Mechanisms in U87 MG Glioblastoma Cells
Global Gene Expression Profiling Reveals Curcumin-Induced Molecular Mechanisms in U87 MG Glioblastoma Cells Open
Curcumin, a major phytochemical derived from Curcuma longa, has been shown to enhance the efficacy of chemotherapeutic agents such as doxorubicin, 5-fluorouracil, and cisplatin by overcoming drug resistance, making it a promising adjunct i…
View article: Genomic insights into Mediterranean pepper diversity using ddRADSeq
Genomic insights into Mediterranean pepper diversity using ddRADSeq Open
This work investigated the genetic diversity and population structure of 99 pepper lines ( Capsicum annuum L.), acclimated to Mediterranean climate conditions, using double-digest restriction site-associated DNA sequencing (ddRADSeq). The …
View article: Deciphering the dose-dependent effects of thymoquinone on cellular proliferation and transcriptomic changes in A172 glioblastoma cells
Deciphering the dose-dependent effects of thymoquinone on cellular proliferation and transcriptomic changes in A172 glioblastoma cells Open
Glioblastoma multiforme (GBM), the most prevalent primary malignant brain tumor in adults, exhibits a dismal 6.9% five-year survival rate post-diagnosis. Thymoquinone (TQ), the most abundant bioactive compound in Nigella sativa , has been …
View article: Root Proteomics Revealed a Shift in Pathways in Response to Varying Nacl Levels, as an Adaptability to Salt Stress in Pistachio Rootstock Ucb1
Root Proteomics Revealed a Shift in Pathways in Response to Varying Nacl Levels, as an Adaptability to Salt Stress in Pistachio Rootstock Ucb1 Open
View article: Exploring the genomic landscape of gummy stem blight resistance in watermelon through QTL-Seq
Exploring the genomic landscape of gummy stem blight resistance in watermelon through QTL-Seq Open
Identifying significant loci associated with GSB resistance has facilitated the development of PACE assays, which will aid in breeding GSB-resistant watermelon cultivars. These findings provide critical insights into the genetic basis of G…
View article: Cleaved Amplified Polymorphic Sequence Markers in Horticultural Crops: Current Status and Future Perspectives
Cleaved Amplified Polymorphic Sequence Markers in Horticultural Crops: Current Status and Future Perspectives Open
DNA markers have broad applications, including marker-assisted selection (MAS) for breeding new cultivars. Currently, single nucleotide polymorphisms (SNPs) have become a preferred choice of markers for molecular geneticists and breeders. …
View article: Unraveling TRPV1’s Role in Cancer: Expression, Modulation, and Therapeutic Opportunities with Capsaicin
Unraveling TRPV1’s Role in Cancer: Expression, Modulation, and Therapeutic Opportunities with Capsaicin Open
Cancer is a global health challenge with rising incidence and mortality rates, posing significant concerns. The World Health Organization reports cancer as a leading cause of death worldwide, contributing to nearly one in six deaths. Cance…
View article: Antioxidant activities, dietary nutrients, and yield potential of bitter gourd (Momordica charantia L.) lines in diverse growing environments
Antioxidant activities, dietary nutrients, and yield potential of bitter gourd (Momordica charantia L.) lines in diverse growing environments Open
The biotic and abiotic stresses cause a significant decline in the yield and fruit quality traits, including antioxidants and minerals, of bitter gourd when grown in open fields. Protected cultivation technology has emerged to minimize suc…
View article: Dietary Curcumin Intake and Its Effects on the Transcriptome and Metabolome of Drosophila melanogaster
Dietary Curcumin Intake and Its Effects on the Transcriptome and Metabolome of Drosophila melanogaster Open
Curcumin, a polyphenol derived from Curcuma longa, used as a dietary spice, has garnered attention for its therapeutic potential, including antioxidant, anti-inflammatory, and antimicrobial properties. Despite its known benefits, the preci…
View article: Widening Genetic Diversity Using Embryo Rescue in Cucurbit Crops: A Review
Widening Genetic Diversity Using Embryo Rescue in Cucurbit Crops: A Review Open
Embryo rescue is a vital technique in cucurbit breeding and propagation, addressing challenges such as embryo abortion, poor seed viability, and incompatibility barriers. This method involves the excision of immature embryos from seeds fol…
View article: From genes to ecosystems: Decoding plant tolerance mechanisms to arsenic stress
From genes to ecosystems: Decoding plant tolerance mechanisms to arsenic stress Open
Arsenic (As), a metalloid of considerable toxicity, has become increasingly bioavailable through anthropogenic activities, raising As contamination levels in groundwater and agricultural soils worldwide. This bioavailability has profound i…
View article: Deciphering the Dose-Dependent Effects of Thymoquinone on Transcriptomic Changes and Cellular Proliferation in Glioblastoma
Deciphering the Dose-Dependent Effects of Thymoquinone on Transcriptomic Changes and Cellular Proliferation in Glioblastoma Open
Glioblastoma multiforme (GBM), the most prevalent primary malignant brain tumor in adults, exhibits a dismal 6.9% five-year survival rate post-diagnosis. Thymoquinone (TQ), the most abundant bioactive compound in Nigella Sativa, has been e…
View article: Capsaicin Responses in Drosophila: Exploring a Non-Trpv1 Model
Capsaicin Responses in Drosophila: Exploring a Non-Trpv1 Model Open
View article: Effects of Mars Global Simulant (MGS-1) on Growth and Physiology of Sweet Potato: A Space Model Plant
Effects of Mars Global Simulant (MGS-1) on Growth and Physiology of Sweet Potato: A Space Model Plant Open
Growing food autonomously on Mars is challenging due to the Martian soil’s low nutrient content and high salinity. Understanding how plants adapt and evaluating their nutritional attributes are pivotal for sustained Mars missions. This res…
View article: Genetic Tapestry of Capsicum Fruit Colors: A Comparative Analysis of Four Cultivated Species
Genetic Tapestry of Capsicum Fruit Colors: A Comparative Analysis of Four Cultivated Species Open
Peppers (Capsicum spp.) rank among the most widely consumed spices globally. Fruit color, serving as a determinant for use in food colorants and cosmeceuticals and an indicator of nutritional content, significantly influences market qualit…
View article: Effects of Mars Global Simulant (MGS-1) on Growth and Physiology of Sweet Potato: A Space Model Plant
Effects of Mars Global Simulant (MGS-1) on Growth and Physiology of Sweet Potato: A Space Model Plant Open
Growing food autonomously on Mars is challenging due to the Martian soil's low nutrient content and high salinity. Understanding how plants adapt and evaluating their nutritional attributes are pivotal for sustained Mars missions. Thi…
View article: From Fruit Waste to Medical Insight: The Comprehensive Role of Watermelon Rind Extract on Renal Adenocarcinoma Cellular and Transcriptomic Dynamics
From Fruit Waste to Medical Insight: The Comprehensive Role of Watermelon Rind Extract on Renal Adenocarcinoma Cellular and Transcriptomic Dynamics Open
Cancer researchers are fascinated by the chemistry of diverse natural products that show exciting potential as anticancer agents. In this study, we aimed to investigate the anticancer properties of watermelon rind extract (WRE) by examinin…
View article: <i>Woolly</i>mutation with<i>Get02</i>locus overcomes the polygenic nature of trichome-based pest resistance in tomato
<i>Woolly</i>mutation with<i>Get02</i>locus overcomes the polygenic nature of trichome-based pest resistance in tomato Open
Type-IV glandular trichomes, which only occur in the juvenile phase of tomato development, produce acylsugars (AS) that broadly protect against arthropod herbivory. Previously, we introgressed the capacity to retain type-IV trichomes in th…
View article: A Genome-Wide Identification and Comparative Analysis of the Heavy-Metal-Associated Gene Family in Cucurbitaceae Species and Their Role in Cucurbita pepo under Arsenic Stress
A Genome-Wide Identification and Comparative Analysis of the Heavy-Metal-Associated Gene Family in Cucurbitaceae Species and Their Role in Cucurbita pepo under Arsenic Stress Open
The heavy-metal-associated (HMA) proteins are a class of PB1-type ATPases related to the intracellular transport and detoxification of metals. However, due to a lack of information regarding the HMA gene family in the Cucurbitaceae family,…
View article: Genome-Wide Identification and Comparative Analysis of the HMA Gene Family in Cucurbitaceae Species and Their Role in <em>Cucurbita pepo</em> under Arsenic Stress
Genome-Wide Identification and Comparative Analysis of the HMA Gene Family in Cucurbitaceae Species and Their Role in <em>Cucurbita pepo</em> under Arsenic Stress Open
The heavy-metal-associated (HMA) proteins are a class of PB1-Type ATPases related to the intracellular transport and detoxification of metals. However, due to a lack of information regarding the HMA gene family in the Cucurbitaceae family,…