Explanipedia

Dual Nephroprotective Strategy of Dapagliflozin and Telmisartan in the Management of Diabetic Kidney Disease: A Comprehensive Review Open

Yachita Rajwadwala, Priyanka Patil, Umesh Upadhyay · 2025

Gastro-retentive drug delivery systems: Modern insights on approaches and applications Open

Roshan Patel, Chainesh Shah, N. Chauhan Nidhi, Umesh Upadhyay · 2025

The pharmaceutical research sector is highly interested in oral gastro-retentive dose formulations. The significance of gastro-retentive drug delivery systems (GRDDS) has grown as these systems enhance patient compliance and improve the th…

Development and Characterization of Film Forming Spray of 5% Minoxidil for Baldness Due to Androgenetic Alopecia Open

Binod Kurmi, Saima Kamran Pathan, Siddhi Upadhyay, Umesh Upadhyay · 2024

Microemulsions in Pharmaceutical Applications: A Comprehensive Review of Formulation, Stability, And Delivery Systems Open

Bhargav Parmar, Drashti Dave, Chainesh Shah, Umesh Upadhyay · 2024

Solid Dispersion: A Novel Technique to Enhancement of Solubility Open

Kulkarni Bhavna Dilipbhai, Chainesh Shah, Umesh Upadhyay · 2024

Development and Validation of Analytical Method for Simultaneous Estimation of Dapagliflozin Propanediol Monohydrate and Sitagliptin Phosphate Monohydrate in Tablet Dosage Form Open

Axita Parmar, Priyanka Patil, K. B. Soni, Chainesh Shah, Umesh Upadhyay · 2024

Optimizing Amphotericin B Invasomes: Critical Quality Attributes using Plackett Burman Design Open

Priyank Kumar M Patel, Mansiben M Patel, Chainesh Shah, Umesh Upadhyay · 2024

A Review of Analytical Methods for Determination of Antidiabetic and Antihypertensive Drugs in Pharmaceuticals Open

Tadvi Nidhi, Krishna Kalsara, Umesh Upadhyay · 2024

SGLT2 inhibitors are generally well-tolerated, with low rates of hypoglycemia. However, adverse effects such as genital mycotic infections and volume depletion-related events may occur, particularly in older adults. Beta-blockers reduce th…

Film Forming Spray: A Comprehensive Review Open

Priyanka Mohite, Harshil Patel, Mansi Patel, Chainesh Shah, Umesh Upadhyay · 2023

In comparison to traditional topical preparations, film-forming sprays have a number of benefits, including uniform drug distribution and dose, enhanced bioavailability, decreased incidence of irritation, continuous drug release, and quick…

Bigels: A newer system – An opportunity for topical application Open

Jigar Vyas, Nensi Raytthatha, Isha Shah, Umesh Upadhyay · 2022

Introduction: A gel is a solid or semisolid system composed of at least two parts, namely a condensed mass containing and interpenetrating a liquid. Hydrogel, emulgel and organogel are novel gel systems that are widely known but have some …

A Review on Coconut Oil : An Essential Oil for all Purposes Open

Prince Pal, Dikshit Rathva, Devendra Parmar, Juhil Patel, Siddhi Upadhyay , et al. · 2021

Coconut oil is produced by crushing copra, the dried kernel, which contains about 60-65% of the oil. The oil has the natural sweet taste of coconut and contains 92% of saturated fatty acids (in the form of triglycerides), most of the…

Optimization of floating bilayered tablets of Ketorolac Tromethamine Open

Hitesh Jain, Kinjal T. Patel, Neha Savant, Umesh Upadhyay · 2017

Objective: The aim of the present study was to formulate the floating bilayer tablets of Ketorolac tromethamine, first immediate release layer and second sustained release floating layer which would provide initial loading dose of drug and…

FORMULATION AND EVALUATION OF BILAYER TABLETS OF BACLOFEN USING SYNTHETIC POLYMERS Open

Priti K Makwana, Krishna B. Patel, Jigar Vyas, Umesh Upadhyay · 2015

Aim of study was to develop bilayer drug delivery for treatment of spasticity by delivering loading and maintenance dose for fast achievement of peak plasma concentration and maintaining the same respectively. The prepared drug loaded bila…

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