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The Role of Therapeutic Plasma Exchange in the Management of Myeloma-Related Cast Nephropathy: A 10-Year Real-World Cohort Study Open
Background: Renal impairment is a frequent and severe complication of multiple myeloma, most commonly caused by light-chain cast nephropathy. Therapeutic plasma exchange (TPE) has been proposed as an adjunctive approach to rapidly reduce c…
Morbidities in β-thalassemia intermedia across the spectrum of disease severity: A nationwide study in Türkiye Open
Introduction Accumulated data show that anemia caused by ineffective erythropoiesis and iron overload is linked to multiple morbidities, significantly reducing quality of life in β-thalassemia intermedia (β-TI). The spectrum of β-TI varies…
View article: Clinical Characteristics, Treatment Approaches, and Survival Predictors in Adult Acute Myeloid Leukemia: Interim Results from the Turkish Society of Hematology AML Registry
Clinical Characteristics, Treatment Approaches, and Survival Predictors in Adult Acute Myeloid Leukemia: Interim Results from the Turkish Society of Hematology AML Registry Open
Background: Acute myeloid leukemia (AML) is an aggressive and biologically diverse hematologic cancer that disproportionately affects older individuals. Despite advances in molecular profiling and therapy, long-term outcomes remain unsatis…
Real-World Outcomes of Antifungal Prophylaxis in Adult Acute Lymphoblastic Leukemia Patients: A Multicenter Comparison of the Use of Fluconazole and Micafungin Open
Background: Adult acute lymphoblastic leukemia (ALL) patients are at increased risk of invasive fungal infections (IFIs) due to intensive therapy and prolonged neutropenia. While pediatric guidelines support administering fluconazole or mo…
Real-World Outcomes of Antifungal Prophylaxis in Adult Acute Lymphoblastic Leukemia: A Multicenter Comparison of Fluconazole and Micafungin Open
Background: Adult acute lymphoblastic leukemia (ALL) patients are at increased risk of invasive fungal infections (IFIs) due to intensive therapy and prolonged neutropenia. While pediatric guidelines support fluconazole or mold-active agen…
View article: Clinical Manifestations, Treatment Characteristics and Clinical Outcome in Patients with Acquired Thrombotic Thrombocytopenic Purpura (aTTP) in the Real-World Setting: An Interim Analysis of the Turkish aTTP Registry
Clinical Manifestations, Treatment Characteristics and Clinical Outcome in Patients with Acquired Thrombotic Thrombocytopenic Purpura (aTTP) in the Real-World Setting: An Interim Analysis of the Turkish aTTP Registry Open
This interim analysis of the nationwide Turkish iTTP Registry study provides valuable data on real-world clinical practices in the diagnosis and management of iTTP at different hematology clinics across the country.
Infection Burden and Survival Outcomes in Multiple Myeloma Patients with Acquired Hypogammaglobulinemia Receiving Antibiotic Prophylaxis without IVIG: A Single-Center Real-World Study Open
Infections remain one of the leading causes of morbidity and mortality in patients with multiple myeloma (MM), particularly during the first three months following diagnosis. This study specifically aimed to evaluate the infection burden a…
Survival Outcomes of Patients with Primary Plasma Cell Leukemia in the Era of Proteasome Inhibitors and Immunomodulatory Agents: A Real-Life Multicenter Analysis Open
In this study, as in previous similar studies, we could not see an increased survival trend in pPCL, which is observed in MM. New studies are needed for pPCL, which is likely to increase with new diagnostic criteria, based on current agent…
Features and Relapse/Refractory Disease Risk Factors of Patients with Acquired Thrombotic Thrombocytopenic Purpura in the Western Mediterranean Region of Turkey Open
The importance of parameters that predict and prevent relapse has increased in thrombotic thrombocytopenic purpura (TTP), where response and overall survival rates exceed 90% with current approaches. In this respect, we examined the clinic…
Single Apheresis Session on the 4th Day of Granulocyte Colony-Stimulating Factor Administration Seems Convenient to Collect Enough Peripheral Blood Stem Cells from Healthy Donors Open
Background: To minimize adverse events of peripheral blood stem cell (PBSC) collection in healthy donors, it is reasonable to limit the total dose of granulocyte colony-stimulating factor (G-CSF) and/or the number of apheresis days without…
Could the 3′UTR+101G>C Mutation Detected in Two Sibling Cases Be a Mutation Affecting the Clinical Presentation in Thalassemia Patients? Open
Due to letter to aditor, there is no abstract.
Is hemolysis a predictor of complications in patients implanted with a left ventricular assist device? Open
Aim: Life-threatening complications such as intra-device thrombus, infection, bleeding, kidney and liver failure are frequently encountered due to the use of left ventricular assist devices (LVADs). We aimed to determine the incidence of h…
View article: Prospective Real-World Outcomes of Acute Myeloid Leukemia
Prospective Real-World Outcomes of Acute Myeloid Leukemia Open
Background: It is evident that treatment outcomes improve with the clinical studies, in this study we aimed to investigate the demographics and treatment modalities of the acute myeloid leukemia (AML) patients in a large population-based c…
P1073: A NEW SCORING SYSTEM TO PREDICT SURVIVAL IN ELDERLY ADVANCED STAGE HODGKIN LYMPHOMA PATIENTS: STUDY BY TURKISH SOCIETY OF HAEMATOLOGY LYMPHOMA ACADEMY WORKING GROUP Open
Topic: 17. Hodgkin lymphoma - Clinical Background: Scoring methods are used to predict the prognosis of patients with cHL These predictive scoring methods do not, however, primarily apply to elderly patients. New prognostic scoring (PS) me…
A Rare Nephrotic Syndrome Related to Chronic Lymphocytic Leukemia: Focal Segmental Glomerulosclerosis Open
Chronic lymphocytic leukemia (CLL) is a hematological disease characterized by the proliferation of monoclonal B-lymphocytes. Although autoimmune complications such as autoimmune hemolytic anemia and immune thrombocytopenia are common in C…
The Frequency of Fabry Disease in Hemodialysis Patients in The Western Mediterranean Region of Turkey Open
Aims: The aim of the present study was to identify patients with chronic kidney disease of unknown etiology or of other detected etiology among those who were undergoing hemodialysis in the Western Mediterranean region and to detect the pr…
Clinical and Survival Outcomes in Patients with Supra-Diaphragmatic Vs İnfra-Diaphragmatic Diffuse Large B Cell Lymphoma Open
Erken evre diffüz büyük B hücreli lenfoma (DBBHL), tüm DBBHL olgularının yaklaşık %30'unu oluşturur. Bu çalışma, birinci basamak rituksimab, siklofosfamid, doksorubisin, vinkristin ve prednizon (R-CHOP) ile tedavi edilen erken evre DBBHL t…
A Rare Paraneoplastic Condition in Hodgkin Lymphoma; Evans Syndrome and Literature Review Open
Evans syndrome (ES) is a spectrum of diseases in which the combination of autoimmune hemolytic anemia and immune thrombocytopenia or sometimes neutropenia. ES has been accepted usually as an idiopathic condition, but it may be secondary. T…
Distribution of transient receptor potential vanilloid-1 channels in gastrointestinal tract of patients with morbid obesity Open
The expression of TRPV1 is unchanged in the gastroduodenal mucosa of morbidly obese patients demonstrating that drugs targeting TRPV1 may be effective in these patients.
View article: Does Immunohistochemically CD5 Positivity Matter In Diffuse Large B-Cell Lymphoma Patients? Turkish Multicenter Study
Does Immunohistochemically CD5 Positivity Matter In Diffuse Large B-Cell Lymphoma Patients? Turkish Multicenter Study Open
Background: Diffuse large B-cell lymphoma (DLBCL) is the most common sub-type of Non-Hodgkin lymphomas (NHL) and it is a very heterogeneous group of diseases. CD5 positivity is profound in a substantial patient population in DLBCL. In this…
View article: Clinical Characteristics and Outcomes of COVID-19 in Turkish Patients with Hematological Malignancies
Clinical Characteristics and Outcomes of COVID-19 in Turkish Patients with Hematological Malignancies Open
Patients with hematological malignancy infected with SARS-CoV-2 have an increased risk of severe disease and mortality.
Azacytidine for Concurrent Acute Monocytic Leukemia and Multiple Myeloma in an Elderly Patient Open
Simultaneous occurrence of MM and AML is a rare entity. 1,2Herein, we report an elderly patient with simultaneous MM and AML, successfully treated with azacytidine.