Unnikrishnan Prathapadas
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View article: Evaluation of Cardiac Function in Patients with Supratentorial Tumors and Raised Intracranial Pressure: HABIT-ICP, a Prospective Observational Study Using Transthoracic Echocardiography
Evaluation of Cardiac Function in Patients with Supratentorial Tumors and Raised Intracranial Pressure: HABIT-ICP, a Prospective Observational Study Using Transthoracic Echocardiography Open
Objective An acute increase in intracranial pressure (ICP) has been shown to affect cardiac function due to brain ischemia and the associated increased sympathetic activity. However, there is limited literature on the changes in cardiac fu…
View article: Evaluation of Cerebral Perfusion Pressure, Cerebral Blood Flow, and Cerebral Oxygenation at Different Head of Bed Positions Using Transcranial Doppler and Near-Infrared Spectroscopy in Postoperative Neurosurgical Patients
Evaluation of Cerebral Perfusion Pressure, Cerebral Blood Flow, and Cerebral Oxygenation at Different Head of Bed Positions Using Transcranial Doppler and Near-Infrared Spectroscopy in Postoperative Neurosurgical Patients Open
Postoperative nursing with positions up to 60° HOB can be tried in indicated patients following elective neurosurgery when complemented with CBF velocity and rSO2 monitoring and in whom CPP-guided therapy is not preferred.
View article: A prospective-randomized placebo-controlled trial comparing the effects of nebulized dexmedetomidine v/s dexmedetomidine-lignocaine mixture on intraoperative hemodynamics and surgical field quality in patients undergoing endoscopic transnasal transsphenoidal pituitary tumor surgery
A prospective-randomized placebo-controlled trial comparing the effects of nebulized dexmedetomidine v/s dexmedetomidine-lignocaine mixture on intraoperative hemodynamics and surgical field quality in patients undergoing endoscopic transnasal transsphenoidal pituitary tumor surgery Open
Background: During transnasal transsphenoidal pituitary surgery (TNTSS), the primary objective is to maintain stable hemodynamics while ensuring ideal surgical conditions. This study aimed to investigate the effect of nebulized dexmedetomi…
View article: Evaluation of markers of cerebral oxygenation and metabolism in patients undergoing clipping of cerebral aneurysm under total intravenous anesthesia versus inhalational anesthesia: A prospective randomized trial (COM-IVIN trial)
Evaluation of markers of cerebral oxygenation and metabolism in patients undergoing clipping of cerebral aneurysm under total intravenous anesthesia versus inhalational anesthesia: A prospective randomized trial (COM-IVIN trial) Open
INTRODUCTION: Anesthetic goals in patients undergoing clipping of cerebral aneurysm include maintenance of cerebral blood flow, oxygenation, and metabolism to avoid cerebral ischemia and maintenance of hemodynamic stability. We intend to s…
View article: Electrocardiographic changes in patients with raised intracranial pressure from supratentorial brain tumors
Electrocardiographic changes in patients with raised intracranial pressure from supratentorial brain tumors Open
Objectives: A wide variety of electrocardiographic (ECG) changes has been described in the context of neurological catastrophe. There has been diverse and plentiful literature emphasizing the cardiac changes in acute cerebrovascular events…
View article: Anaesthesia for ventriculoperitoneal shunt surgery in a craniovertebral junction anomaly patient with arrested hydrocephalus: Stability is safety
Anaesthesia for ventriculoperitoneal shunt surgery in a craniovertebral junction anomaly patient with arrested hydrocephalus: Stability is safety Open
View article: A Comparative Study to Evaluate the Efficacy of Virtual Versus Direct Airway Assessment in the Preoperative Period in Patients Presenting for Neurosurgery: A Quest for Safer Preoperative Practice in Neuroanesthesia in the Backdrop of the COVID-19 Pandemic!
A Comparative Study to Evaluate the Efficacy of Virtual Versus Direct Airway Assessment in the Preoperative Period in Patients Presenting for Neurosurgery: A Quest for Safer Preoperative Practice in Neuroanesthesia in the Backdrop of the COVID-19 Pandemic! Open
Objectives Neurosurgical patients with cervical spine pathologies, craniofacial and craniovertebral junction anomalies, recurrent cervical spine, and posterior fossa surgeries frequently present with an airway that is anticipated to be dif…
View article: Anesthetic Management of Hashimoto's Encephalopathy Presenting for Spine Surgery
Anesthetic Management of Hashimoto's Encephalopathy Presenting for Spine Surgery Open
Hashimoto's encephalopathy (HE) is a rare neuroendocrine disorder, and there are no reports regarding anesthetic implications in a patient diagnosed with HE. These patients can have a plethora of systemic manifestations involving cardiovas…
View article: A Rare Case of Rhinocerebral Mucormycosis Presenting as Garcin Syndrome and Acute Ischemic Stroke
A Rare Case of Rhinocerebral Mucormycosis Presenting as Garcin Syndrome and Acute Ischemic Stroke Open
Nagendra V, Thakkar KD, Prasad Hrishi A, Prathapadas U. A Rare Case of Rhinocerebral Mucormycosis Presenting as Garcin Syndrome and Acute Ischemic Stroke. Indian J Crit Care Med 2020;24(11):1137-1138.
View article: Finding the Calm in the Chaos: An Institutional Protocol for Anesthetic Management of a Patient for Neurosurgery during Coronavirus Disease 2019 Pandemic
Finding the Calm in the Chaos: An Institutional Protocol for Anesthetic Management of a Patient for Neurosurgery during Coronavirus Disease 2019 Pandemic Open
“Coronavirus disease 2019” (COVID-19) transmitted by a novel coronavirus via contact or droplet spread is a highly infectious disease, the containment of which requires vigilance and stringent infection control policies. In the backdrop of…
View article: Effect of Low-Dose Dexmedetomidine on the Anesthetic and Recovery Profile of Sevoflurane-Based Anesthesia in Patients Presenting for Supratentorial Neurosurgeries: A Randomized Double-Blind Placebo-Controlled Trial
Effect of Low-Dose Dexmedetomidine on the Anesthetic and Recovery Profile of Sevoflurane-Based Anesthesia in Patients Presenting for Supratentorial Neurosurgeries: A Randomized Double-Blind Placebo-Controlled Trial Open
Background Dexmedetomidine could be a suitable adjuvant in neuroanesthesia due to its analgesic and anesthetic-sparing properties with the added advantage of facilitating intraoperative neuromonitoring. However, its recovery profile is sti…
View article: Effect of Pregabalin on Perioperative Headache in Patients with Aneurysmal Subarachnoid Hemorrhage: A Randomized Double-Blind, Placebo-Controlled Trial
Effect of Pregabalin on Perioperative Headache in Patients with Aneurysmal Subarachnoid Hemorrhage: A Randomized Double-Blind, Placebo-Controlled Trial Open
Background Patients with acute aneurysmal subarachnoid hemorrhage (aSAH) experience excruciating headache that is difficult to manage in resource-constrained settings. Pregabalin’s (β-isobutyl-GABA) analgesic, antiepileptic, and antiemetic…
View article: Anoxic Brain Injury: The Abominable Malady
Anoxic Brain Injury: The Abominable Malady Open
Anoxic brain injury (ABI) is an important cause of prolonged hospital stay and morbidity across the globe. It is a sequel of major systemic insults resulting from various etiologies, such as reduced oxygen availability, insufficient cerebr…
View article: A0045 Anesthetic Management of Patients Presenting with Vein of Galen Malformation for Endovascular/Surgical Treatment: A 10-Year Retrospective Analysis
A0045 Anesthetic Management of Patients Presenting with Vein of Galen Malformation for Endovascular/Surgical Treatment: A 10-Year Retrospective Analysis Open
Background: The vein of Galen aneurysmal malformation (VGAM) is a rare arteriovascular malformation in which a dilated median prosencephalic vein provides a low resistance conduit for intracerebral blood flow, resulting in high output card…
View article: An Uncommon Cause of Intraoperative Hypotension: Delayed Red Man Syndrome
An Uncommon Cause of Intraoperative Hypotension: Delayed Red Man Syndrome Open
Intraoperative hypotension is commonly encountered under anesthesia. Varied causation of intraoperative hypotension can often delay the recognition of its cause. Vancomycin, a bactericidal antibiotic and often used in neurosurgical setting…
View article: A study comparing propofol auto-coinduction and standard propofol induction in patients undergoing general anesthesia without midazolam pretreatment: A prospective randomized control trial
A study comparing propofol auto-coinduction and standard propofol induction in patients undergoing general anesthesia without midazolam pretreatment: A prospective randomized control trial Open
In our study, we found that the induction dose requirement of propofol was significantly lower in the auto-coinduction group when compared to the conventional induction group. The auto-coinduction technique offered a stable hemodynamic pro…