Usha Lingappa
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View article: Influence of environment and mineralogy on euendolithic microboring patterns
Influence of environment and mineralogy on euendolithic microboring patterns Open
Euendolithic microorganisms, capable of bioerosion in carbonate substrates, play an important role in modern marine ecosystems and have a fossil record extending into deep time. Understanding the factors driving microboring behaviour is es…
View article: Mono-mix strategy enables comparative proteomics of a cross-kingdom microbial symbiosis
Mono-mix strategy enables comparative proteomics of a cross-kingdom microbial symbiosis Open
Cross-kingdom microbial symbioses, such as those between algae and bacteria, are key players in biogeochemical cycles. The molecular changes during initiation and establishment of symbiosis are of great interest, but quantitatively monitor…
View article: Diversity and evolution of nitric oxide reduction in bacteria and archaea
Diversity and evolution of nitric oxide reduction in bacteria and archaea Open
Nitrous oxide is a potent greenhouse gas whose production is catalyzed by nitric oxide reductase (NOR) members of the heme-copper oxidoreductase (HCO) enzyme superfamily. We identified several previously uncharacterized HCO families, four …
View article: A pan-respiratory antiviral chemotype targeting a transient host multi-protein complex
A pan-respiratory antiviral chemotype targeting a transient host multi-protein complex Open
We present a novel small molecule antiviral chemotype that was identified by an unconventional cell-free protein synthesis and assembly-based phenotypic screen for modulation of viral capsid assembly. Activity of PAV-431, a representative …
View article: Scarcity of fixed carbon transfer in a model microbial phototroph-heterotroph interaction
Scarcity of fixed carbon transfer in a model microbial phototroph-heterotroph interaction Open
Although the green alga Chlamydomonas reinhardtii has long served as a reference organism, few studies have interrogated its role as a primary producer in microbial interactions. Here, we quantitatively investigated C. reinhardtii’s capaci…
View article: Scarcity of fixed carbon transfer in a model microbial phototroph–heterotroph interaction
Scarcity of fixed carbon transfer in a model microbial phototroph–heterotroph interaction Open
Although the green alga Chlamydomonas reinhardtii has long served as a reference organism, few studies have interrogated its role as a primary producer in microbial interactions. Here, we quantitatively investigated C. reinhardtii’s capaci…
View article: Isotopically labelled inorganic carbon delivered to algal cultures via bubbler bottle v1
Isotopically labelled inorganic carbon delivered to algal cultures via bubbler bottle v1 Open
This protocol describes a method for delivering labelled inorganic carbon as 13CO2 to algal cultures by bubbling air through a solution of H13CO3-, and then into the culture. We developed this method to deliver label to cultures grown unde…
View article: Of Microbes and Megastorms
Of Microbes and Megastorms Open
The earliest ecosystems we know of were built entirely by microscopic lifeforms. Similar ecosystems that exist today help us understand the history of life on our planet. We set out to investigate their sensitivity to sea level change, but…
View article: Geomorphic and environmental controls on microbial mat fabrics on Little Ambergris Cay, Turks and Caicos Islands
Geomorphic and environmental controls on microbial mat fabrics on Little Ambergris Cay, Turks and Caicos Islands Open
To interpret microbially influenced paleoenvironments in the sedimentary record, it is crucial to understand what processes control the development of microbial mats in modern environments. This article reports results from a multiyear stu…