Mehdi Abbasi
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View article: Comparison of Autologous Platelet-Rich Plasma (PRP)-Soaked Dressing vs. Saline-Soaked Dressing in the Healing of Diabetic Foot Ulcer
Comparison of Autologous Platelet-Rich Plasma (PRP)-Soaked Dressing vs. Saline-Soaked Dressing in the Healing of Diabetic Foot Ulcer Open
Diabetic foot ulcer (DFU) remains one of the most debilitating complications of diabetes mellitus, contributing significantly to morbidity, disability, and healthcare costs. Impaired wound healing due to neuropathy, ischemia, and infection…
View article: E-1 | Meta-Analysis Assessing Outcomes of Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement in Patients With Severe Symptomatic Aortic Valve Stenosis
E-1 | Meta-Analysis Assessing Outcomes of Transcatheter Aortic Valve Implantation Versus Surgical Aortic Valve Replacement in Patients With Severe Symptomatic Aortic Valve Stenosis Open
View article: Evaluation of Sperm DNA Fragmentation in Oligoasthenoteratozoospermia Patients Using Two Different Techniques: TUNEL and Sperm Chromatin Dispersion Assays
Evaluation of Sperm DNA Fragmentation in Oligoasthenoteratozoospermia Patients Using Two Different Techniques: TUNEL and Sperm Chromatin Dispersion Assays Open
Background: Oligoasthenoteratozoospermia (OAT) is the most prevalent male infertility condition that is mainly caused by sperm DNA fragmentation (SDF). This study compared the sensitivity and effectiveness of two different approaches for a…
View article: Twenty-Year Disparity Trends in United States Stroke Death Rate by Age, Race/Ethnicity, Geography, and Socioeconomic Status
Twenty-Year Disparity Trends in United States Stroke Death Rate by Age, Race/Ethnicity, Geography, and Socioeconomic Status Open
Improvements in the stroke death rate in the United States are slowing and even reversing in younger individuals and many US counties. County-level increases in stroke death rate were associated with distinct social determinants of health …
View article: Large Vessel Occlusion Stroke due to Intracranial Atherosclerotic Disease: Identification, Medical and Interventional Treatment, and Outcomes
Large Vessel Occlusion Stroke due to Intracranial Atherosclerotic Disease: Identification, Medical and Interventional Treatment, and Outcomes Open
Large vessel occlusion stroke due to underlying intracranial atherosclerotic disease (ICAD-LVO) is prevalent in 10 to 30% of LVOs depending on patient factors such as vascular risk factors, race and ethnicity, and age. Patients with ICAD-L…
View article: A swine model of pulmonary embolism with human-derived thrombi
A swine model of pulmonary embolism with human-derived thrombi Open
Objectives: The development and evaluation of percutaneous thrombectomy devices for pulmonary embolism (PE) pose a need for standardized large in vivo models with representative anatomical and physiological conditions and clots analogs. In…
View article: Secondary Ischemic Stroke Prevention
Secondary Ischemic Stroke Prevention Open
View article: Dynamique des agrégats érythrocytaires dans des conditions physiopathologiques
Dynamique des agrégats érythrocytaires dans des conditions physiopathologiques Open
This thesis contributes to the understanding od dynamics and rheology of red blood cell (RBC) aggregates. We adopted 2D and 3D capsule model to mimic RBC. In addition to simulations, we carried out microfluidic experiments. The main goal o…
View article: Review of: "Investigation of the effects of wet cupping therapy on some inflammatory factors in patients affected by non-alcoholic fatty liver disease (NAFLD): A quasi-experimental trial study with self-controls"
Review of: "Investigation of the effects of wet cupping therapy on some inflammatory factors in patients affected by non-alcoholic fatty liver disease (NAFLD): A quasi-experimental trial study with self-controls" Open
View article: In vitro Complete Differentiation of Human Spermatogonial Stem Cells to Morphologic Spermatozoa Using a Hybrid Hydrogel of Agarose and laminin
In vitro Complete Differentiation of Human Spermatogonial Stem Cells to Morphologic Spermatozoa Using a Hybrid Hydrogel of Agarose and laminin Open
Background Spermatogenesis refers to the differentiation of spermatogonial stem cells (SSCs) located in the basal part of seminiferous tubules into haploid spermatozoa. Prerequisites for in vitro spermatogenesis include an extracellular ma…
View article: E-218 Risk factors of unexplained early neurological deterioration following endovascular treatment in patient with large vessel occlusion: systematic review and meta-analysis
E-218 Risk factors of unexplained early neurological deterioration following endovascular treatment in patient with large vessel occlusion: systematic review and meta-analysis Open
Background Endovascular thrombectomy (EVT) is an effective treatment for acute ischemic stroke attributable largevessel occlusion. However early neurological deterioration (END) remains a serious clinical issue strongly associated with poo…
View article: Risk Factors of Futile Recanalization Following Endovascular Treatment in Patients With Large‐Vessel Occlusion: Systematic Review and Meta‐Analysis
Risk Factors of Futile Recanalization Following Endovascular Treatment in Patients With Large‐Vessel Occlusion: Systematic Review and Meta‐Analysis Open
Background Although successful recanalization (modified Thrombolysis in Cerebral Infarction score 2b–3) can be achieved in >80% of patients experiencing stroke attributable to large‐vessel occlusion, up to 50% of patients may develop poor …
View article: Intra-procedural cerebral sinus thrombosis during endovascular treatment of idiopathic intracranial hypertension
Intra-procedural cerebral sinus thrombosis during endovascular treatment of idiopathic intracranial hypertension Open
Stenting of the intracranial venous sinuses has shown promising results in patients who are refractory to medical treatment of idiopathic intracranial hypertension (IIH). Among the reported complications associated with this procedure, in-…
View article: An in vitro model for Extracellular DNA Traps (ETs)-rich Human Thrombus Analogs
An in vitro model for Extracellular DNA Traps (ETs)-rich Human Thrombus Analogs Open
Background Extracellular DNA traps (ETs) have important implications in both thrombosis and thrombolysis. Thus, developing benchtop thrombus analogs that recapitulate clinical ETs is potentially of great value for preclinical development a…
View article: Arterial Collapse during Thrombectomy for Stroke: Clinical Evidence and Experimental Findings in Human Brains and In Vivo Models
Arterial Collapse during Thrombectomy for Stroke: Clinical Evidence and Experimental Findings in Human Brains and In Vivo Models Open
Arterial collapse does occur during aspiration thrombectomy and is more likely to happen with larger catheters, lower perfusion pressure, and smaller arteries.
View article: Postprocedural Thrombosis following Endovascular Treatment of Intracranial Aneurysm with Flow Diverters or Coiling: A Histologic Study
Postprocedural Thrombosis following Endovascular Treatment of Intracranial Aneurysm with Flow Diverters or Coiling: A Histologic Study Open
Endovascular treatment of aneurysms with flow diverters or coiling is sometimes complicated by intraprocedural or postprocedural thrombosis along or within the devices. Thrombus composition and structure associated with such complications …
View article: Quantification of clot spatial heterogeneity and its impact on thrombectomy
Quantification of clot spatial heterogeneity and its impact on thrombectomy Open
Background Compositional and structural features of retrieved clots by thrombectomy can provide insight into improving the endovascular treatment of ischemic stroke. Currently, histological analysis is limited to quantification of composit…
View article: Correlation of Neutrophil to Lymphocyte Ratio with Expression of Neutrophil Extracellular Traps Within Stroke Emboli
Correlation of Neutrophil to Lymphocyte Ratio with Expression of Neutrophil Extracellular Traps Within Stroke Emboli Open
Background & Purpose It has been hypothesized that circulating neutrophils have a direct correlation with the composition of emboli in acute ischemic stroke (AIS). The aim of this study is to evaluate the association between neutrophil-lym…
View article: Diverse thrombus composition in thrombectomy stroke patients with longer time to recanalization
Diverse thrombus composition in thrombectomy stroke patients with longer time to recanalization Open
View article: COVID-19 and Selenium Deficiency: a Systematic Review
COVID-19 and Selenium Deficiency: a Systematic Review Open
View article: Factors Affecting Vagus Nerve Stimulation Outcomes in Epilepsy
Factors Affecting Vagus Nerve Stimulation Outcomes in Epilepsy Open
Epilepsy as a common neurological disease is mostly managed effectively with antiepileptic medications. One-third of patients do not respond to medical treatments requiring alternative therapies. Vagus nerve stimulation (VNS) has been used…
View article: P-005 Clot spatial heterogeneity rather than histologic composition is related to FPE rate
P-005 Clot spatial heterogeneity rather than histologic composition is related to FPE rate Open
Introduction Characteristics of clots from stroke patients have gained a lot of interest in recent years as they could provide insights to improve the endovascular and medical management of ischemic stroke. Histology have been used to quan…
View article: E-089 Systematic review and meta-analysis of factors associated with distal clot migration
E-089 Systematic review and meta-analysis of factors associated with distal clot migration Open
Introduction Distal clot migration (DCM) is defined as the moving of an occluding clot from its initial location on pre-procedural imaging to a more distal location, identified on peri-procedural angiographic images. In a recent study, clo…
View article: Mechanisms of fibrinolysis resistance and potential targets for thrombolysis in acute ischaemic stroke: lessons from retrieved stroke emboli
Mechanisms of fibrinolysis resistance and potential targets for thrombolysis in acute ischaemic stroke: lessons from retrieved stroke emboli Open
There has been growing interest and insight into the histological composition of retrieved stroke emboli. One of the main focuses of the stroke clot analysis literature has been the implications of clot composition on mechanical thrombecto…
View article: In Vitro Study of Blood Clot Identification and Composition Assessment by Different Magnetic Resonance Sequences
In Vitro Study of Blood Clot Identification and Composition Assessment by Different Magnetic Resonance Sequences Open
View article: Per-pass analysis of recanalization and good neurological outcome in thrombectomy for stroke: Systematic review and meta-analysis
Per-pass analysis of recanalization and good neurological outcome in thrombectomy for stroke: Systematic review and meta-analysis Open
Background and aim First pass effect (FPE) is defined as achieving a complete recanalization with a single thrombectomy device pass. Although clinically desired, FPE is reached in less than 30% of thrombectomy procedures. Multiple device p…
View article: Endoluminal flow diverters in the treatment of sidewall and bifurcation aneurysm: A systematic review and meta-analysis of complications and angiographic outcomes
Endoluminal flow diverters in the treatment of sidewall and bifurcation aneurysm: A systematic review and meta-analysis of complications and angiographic outcomes Open
Background and aim The use of endoluminal flow diversion in bifurcation aneurysms has been questioned due to the potential for complications and lower occlusion rates. In this study we assessed outcomes of endovascular treatment of intracr…
View article: Histological evaluation of acute ischemic stroke thrombi may indicate the occurrence of vessel wall injury during mechanical thrombectomy
Histological evaluation of acute ischemic stroke thrombi may indicate the occurrence of vessel wall injury during mechanical thrombectomy Open
Background Several animal studies have demonstrated that mechanical thrombectomy (MT) for acute ischemic stroke (AIS) may cause vessel wall injury (VWI). However, the histological changes in human cerebral arteries following MT are difficu…
View article: e-ASPECTS software improves interobserver agreement and accuracy of interpretation of aspects score
e-ASPECTS software improves interobserver agreement and accuracy of interpretation of aspects score Open
Introduction There is increased interest in the use of artificial intelligence-based (AI) software packages in the evaluation of neuroimaging studies for acute ischemic stroke. We studied whether, compared to standard image interpretation …
View article: Novel Human Acute Ischemic Stroke Blood Clot Analogs for In Vitro Thrombectomy Testing
Novel Human Acute Ischemic Stroke Blood Clot Analogs for In Vitro Thrombectomy Testing Open
Red blood cell-rich, fibrin-rich, and platelet-rich clot analogs that mimic clots retrieved from patients with acute ischemic stroke were created in vitro. Differing retrieval outcomes were confirmed using in vitro thrombectomy testing in …