Uta Hanning
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View article: Symptom-Only Localization of Brainstem Ischemia: Large Language Models vs. Neurologists in 109 Diffusion-Weighted Imaging–Positive Cases: A Retrospective Study (Preprint)
Symptom-Only Localization of Brainstem Ischemia: Large Language Models vs. Neurologists in 109 Diffusion-Weighted Imaging–Positive Cases: A Retrospective Study (Preprint) Open
BACKGROUND Localizing brainstem ischemic lesions based solely on neurological symptoms is challenging due to the complex anatomy and variable symptom presentation. Large language models (LLMs) take an emerging role in medical diagnostics …
View article: Aneurysm Specific Working Projections for the Endovascular Treatment of Intracranial Aneurysms—Same Aneurysm, Different Working Projections?”
Aneurysm Specific Working Projections for the Endovascular Treatment of Intracranial Aneurysms—Same Aneurysm, Different Working Projections?” Open
Purpose Despite decades of endovascular treatment (EVT) of intracranial aneurysms (IA), there are no studies regarding the ideal working projections. Possible correlations between suboptimal working projections and procedure-related compli…
View article: DeepISLES: a clinically validated ischemic stroke segmentation model from the ISLES'22 challenge
DeepISLES: a clinically validated ischemic stroke segmentation model from the ISLES'22 challenge Open
Diffusion-weighted MRI is critical for diagnosing and managing ischemic stroke, but variability in images and disease presentation limits the generalizability of AI algorithms. We present DeepISLES , a robust ensemble algorithm developed f…
View article: An Explainable AI Exploration of the Machine Learning Classification of Neoplastic Intracerebral Hemorrhage from Non-Contrast CT
An Explainable AI Exploration of the Machine Learning Classification of Neoplastic Intracerebral Hemorrhage from Non-Contrast CT Open
Intracerebral hemorrhage (ICH) associated with primary and metastatic brain tumors presents a significant challenge in neuro-oncology due to the substantial risk of complications [...]
View article: True versus pseudo-occlusion of the cervical internal carotid artery in acute stroke: A multicenter MR angiography study
True versus pseudo-occlusion of the cervical internal carotid artery in acute stroke: A multicenter MR angiography study Open
Introduction: Differentiating true from pseudo-occlusion of the cervical internal carotid artery (ICA) in acute ischemic stroke patients undergoing thrombectomy is crucial but challenging. We aimed to investigate the ability of contrast-en…
View article: Delayed neurological recovery in ischemic stroke patients undergoing endovascular treatment is associated with baseline hyperglycemia: a treatable cause of the stunned brain phenomenon?
Delayed neurological recovery in ischemic stroke patients undergoing endovascular treatment is associated with baseline hyperglycemia: a treatable cause of the stunned brain phenomenon? Open
Background and aims In ischemic stroke, there is limited data regarding the impact of baseline hyperglycemia on the treatment effect of recanalization on neurological recovery. This study aimed to directly compare—how short- and long-term …
View article: General Anesthesia Versus Conscious Sedation in Thrombectomy Patients With Low NIHSS Anterior Circulation Stroke
General Anesthesia Versus Conscious Sedation in Thrombectomy Patients With Low NIHSS Anterior Circulation Stroke Open
BACKGROUND: The optimal anesthetic approach for patients with acute ischemic stroke with large vessel occlusion but low National Institutes of Health Stroke Scale receiving mechanical thrombectomy remains unclear. We aimed to evaluate the …
View article: Cross-institutional automated multilabel segmentation for acute intracerebral hemorrhage, intraventricular hemorrhage, and perihematomal edema on CT
Cross-institutional automated multilabel segmentation for acute intracerebral hemorrhage, intraventricular hemorrhage, and perihematomal edema on CT Open
Background Precise volume quantification of intracerebral hemorrhage (ICH), intraventricular hemorrhage (IVH), and perihematomal edema (PHE) is a critical parameter for guiding therapy decisions, monitoring therapeutic effects over time, a…
View article: Diagnosis and Differential Diagnosis of Dysglossia, Resonance Disorders and Velopharyngeal Insufficiency
Diagnosis and Differential Diagnosis of Dysglossia, Resonance Disorders and Velopharyngeal Insufficiency Open
View article: End-to-end machine learning based discrimination of neoplastic and non-neoplastic intracerebral hemorrhage on computed tomography
End-to-end machine learning based discrimination of neoplastic and non-neoplastic intracerebral hemorrhage on computed tomography Open
Purpose: To develop and evaluate a fully automated segmentation and classification tool for the discrimination of neoplastic and non-neoplastic intracerebral hemorrhage (ICH) on admission Computed Tomography (CT). Materials and methods: Tw…
View article: A Hybrid Transformer-Convolutional Neural Network for Segmentation of Intracerebral Hemorrhage and Perihematomal Edema on Non-Contrast Head Computed Tomography (CT) with Uncertainty Quantification to Improve Confidence
A Hybrid Transformer-Convolutional Neural Network for Segmentation of Intracerebral Hemorrhage and Perihematomal Edema on Non-Contrast Head Computed Tomography (CT) with Uncertainty Quantification to Improve Confidence Open
Intracerebral hemorrhage (ICH) and perihematomal edema (PHE) are key imaging markers of primary and secondary brain injury in hemorrhagic stroke. Accurate segmentation and quantification of ICH and PHE can help with prognostication and gui…
View article: Mechanical thrombectomy practices in Europe: Insights from a survey of European neuroradiologists from the ESMINT
Mechanical thrombectomy practices in Europe: Insights from a survey of European neuroradiologists from the ESMINT Open
Background and purpose: Mechanical thrombectomy (MT) has revolutionized the prognosis of acute ischemic stroke. Indications for MT are constantly expanding across countries, presenting healthcare professionals, and institutions with the ch…
View article: Cross-Institutional European Evaluation and Validation of Automated Multilabel Segmentation for Acute Intracerebral Hemorrhage and Complications
Cross-Institutional European Evaluation and Validation of Automated Multilabel Segmentation for Acute Intracerebral Hemorrhage and Complications Open
Purpose To evaluate a nnU-Net-based deep learning for automated segmentation of intracerebral hemorrhage (ICH), intraventricular hemorrhage (IVH), and perihematomal edema (PHE) on noncontrast CT scans. Materials and Methods Retrospective d…
View article: Endovascular Thrombectomy Versus Intravenous Thrombolysis of Posterior Cerebral Artery Occlusion Stroke
Endovascular Thrombectomy Versus Intravenous Thrombolysis of Posterior Cerebral Artery Occlusion Stroke Open
Background and Purpose Posterior cerebral artery occlusion (PCAo) can cause long-term disability, yet randomized controlled trials to guide optimal reperfusion strategy are lacking. We compared the outcomes of PCAo patients treated with en…
View article: How much of the variance in functional outcome related to intracerebral hemorrhage volume is already apparent in neurological status at admission?
How much of the variance in functional outcome related to intracerebral hemorrhage volume is already apparent in neurological status at admission? Open
View article: Endovascular Versus Medical Therapy in Posterior Cerebral Artery Stroke: Role of Baseline NIHSS Score and Occlusion Site
Endovascular Versus Medical Therapy in Posterior Cerebral Artery Stroke: Role of Baseline NIHSS Score and Occlusion Site Open
BACKGROUND: Acute ischemic stroke with isolated posterior cerebral artery occlusion (iPCAO) lacks management evidence from randomized trials. We aimed to evaluate whether the association between endovascular treatment (EVT) and outcomes in…
View article: Endovascular Thrombectomy for Large Ischemic Strokes with ASPECTS 0–2: a Meta-analysis of Randomized Controlled Trials
Endovascular Thrombectomy for Large Ischemic Strokes with ASPECTS 0–2: a Meta-analysis of Randomized Controlled Trials Open
Purpose Randomized controlled trials (RCTs) demonstrated a treatment effect of endovascular thrombectomy in acute ischemic stroke with large infarct, commonly defined as an Alberta Stroke Program Early CT Score (ASPECTS) of 3–5. However, d…
View article: A Robust Ensemble Algorithm for Ischemic Stroke Lesion Segmentation: Generalizability and Clinical Utility Beyond the ISLES Challenge
A Robust Ensemble Algorithm for Ischemic Stroke Lesion Segmentation: Generalizability and Clinical Utility Beyond the ISLES Challenge Open
Diffusion-weighted MRI (DWI) is essential for stroke diagnosis, treatment decisions, and prognosis. However, image and disease variability hinder the development of generalizable AI algorithms with clinical value. We address this gap by pr…
View article: Functional MRI brain state occupancy in the presence of cerebral small vessel disease<b>—</b>a pre-registered replication analysis of the Hamburg City Health Study
Functional MRI brain state occupancy in the presence of cerebral small vessel disease<b>—</b>a pre-registered replication analysis of the Hamburg City Health Study Open
We aimed to replicate recent findings on the association between the extent of cerebral small vessel disease (cSVD), functional brain network dedifferentiation, and cognitive impairment. We analyzed demographic, imaging, and behavioral dat…
View article: Assessment of the intrasinusidal volume before and after maxillary sinus augmentation using mri – a pilot study of eight patients
Assessment of the intrasinusidal volume before and after maxillary sinus augmentation using mri – a pilot study of eight patients Open
Purpose The purpose of this study was to evaluate the suitability, accuracy, and reliability of a non-invasive 3-Tesla magnetic resonance imaging technique (3 T-MRI) for the visualization of maxillary sinus grafts in comparison to conventi…
View article: Treatment practice of vasospasm during endovascular thrombectomy: an international survey
Treatment practice of vasospasm during endovascular thrombectomy: an international survey Open
Background and aim The clinical importance and management of vasospasm as a complication during endovascular stroke treatment (EVT) has not been well studied. We sought to investigate current expert opinions in neurointervention and therap…
View article: Effect of short‐ versus long‐term serum glucose levels on early ischemic water homeostasis and functional outcome in patients with large vessel occlusion stroke
Effect of short‐ versus long‐term serum glucose levels on early ischemic water homeostasis and functional outcome in patients with large vessel occlusion stroke Open
Background and purpose In ischemic stroke, the impact of short‐ versus long‐term blood glucose level (BGL) on early lesion pathophysiology and functional outcome has not been assessed. The purpose of this study was to directly compare the …
View article: First‐Line Stent Retriever Versus Contact Aspiration or Combined Technique for Endovascular Therapy of Posterior Cerebral Artery Occlusion Stroke: The PLATO Study
First‐Line Stent Retriever Versus Contact Aspiration or Combined Technique for Endovascular Therapy of Posterior Cerebral Artery Occlusion Stroke: The PLATO Study Open
Background The optimal reperfusion technique in patients with isolated posterior cerebral artery (PCA) occlusion is uncertain. We compared clinical and technical outcomes with first‐line stent retriever (SR), contact aspiration (CA), or co…
View article: Prognostic value of recanalization attempts in endovascular therapy for M2 segment middle cerebral artery occlusions
Prognostic value of recanalization attempts in endovascular therapy for M2 segment middle cerebral artery occlusions Open
Background: There is growing evidence suggesting efficacy of endovascular therapy for M2 occlusions of the middle cerebral artery. More than one recanalization attempt is often required to achieve successful reperfusion in M2 occlusions, a…
View article: Abstract 012: First‐line Stent Retriever Versus Contact Aspiration or Combined Technique for Posterior Cerebral Artery Occlusion EVT
Abstract 012: First‐line Stent Retriever Versus Contact Aspiration or Combined Technique for Posterior Cerebral Artery Occlusion EVT Open
Introduction The optimal reperfusion technique in patients with isolated posterior cerebral artery (PCA) occlusion is uncertain. Previous studies in LVO and MeVO have demonstrated a correlation between good clinical outcomes and the first …
View article: Predictors of functional outcome after thrombectomy for M2 occlusions: a large scale experience from clinical practice
Predictors of functional outcome after thrombectomy for M2 occlusions: a large scale experience from clinical practice Open
Mechanical thrombectomy (MT) for acute ischemic stroke with medium vessel occlusions is still a matter of debate. We sought to identify factors associated with clinical outcome after MT for M2-occlusions based on data from the German Strok…
View article: Interventionelle Therapie der Basilaristhrombose
Interventionelle Therapie der Basilaristhrombose Open
View article: Haemorrhage after thrombectomy with adjuvant thrombolysis in unknown onset stroke depends on high early lesion water uptake
Haemorrhage after thrombectomy with adjuvant thrombolysis in unknown onset stroke depends on high early lesion water uptake Open
Background and purpose In wake-up stroke, CT-based quantitative net water uptake (NWU) might serve as an alternative tool to MRI to guide intravenous thrombolysis with alteplase (IVT). An important complication after IVT is symptomatic int…
View article: Investigating Neurologic Improvement After IV Thrombolysis
Investigating Neurologic Improvement After IV Thrombolysis Open
CT-based measures of the "tissue clock" might identify patients who benefit from IVT more accurately than conventional time windows. Considering the high number of patients with early "tissue clock" (low NWU/CTP mismatch) within an extende…
View article: P152/178 Safety and efficiency of bridging i.v. thrombolysis in M2 occlusions: a propensity-score-matched registry cohort study
P152/178 Safety and efficiency of bridging i.v. thrombolysis in M2 occlusions: a propensity-score-matched registry cohort study Open
Introduction DIRECT-SAFE and SWIFT DIRECT did not show noninferiority of mechanical thrombectomy(MT) alone compared with intravenous thrombolysis(IVT) plus MT. However, for isolated M2-occlusions, data is scarce. Aim of Study This study ai…