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The Role of Therapeutic Plasma Exchange in the Management of Myeloma-Related Cast Nephropathy: A 10-Year Real-World Cohort Study Open
Background: Renal impairment is a frequent and severe complication of multiple myeloma, most commonly caused by light-chain cast nephropathy. Therapeutic plasma exchange (TPE) has been proposed as an adjunctive approach to rapidly reduce c…
View article: Clinical Characteristics, Treatment Approaches, and Survival Predictors in Adult Acute Myeloid Leukemia: Interim Results from the Turkish Society of Hematology AML Registry
Clinical Characteristics, Treatment Approaches, and Survival Predictors in Adult Acute Myeloid Leukemia: Interim Results from the Turkish Society of Hematology AML Registry Open
Background: Acute myeloid leukemia (AML) is an aggressive and biologically diverse hematologic cancer that disproportionately affects older individuals. Despite advances in molecular profiling and therapy, long-term outcomes remain unsatis…
Real-World Outcomes of Antifungal Prophylaxis in Adult Acute Lymphoblastic Leukemia Patients: A Multicenter Comparison of the Use of Fluconazole and Micafungin Open
Background: Adult acute lymphoblastic leukemia (ALL) patients are at increased risk of invasive fungal infections (IFIs) due to intensive therapy and prolonged neutropenia. While pediatric guidelines support administering fluconazole or mo…
Real-World Outcomes of Antifungal Prophylaxis in Adult Acute Lymphoblastic Leukemia: A Multicenter Comparison of Fluconazole and Micafungin Open
Background: Adult acute lymphoblastic leukemia (ALL) patients are at increased risk of invasive fungal infections (IFIs) due to intensive therapy and prolonged neutropenia. While pediatric guidelines support fluconazole or mold-active agen…
Survival Outcomes of Patients with Primary Plasma Cell Leukemia in the Era of Proteasome Inhibitors and Immunomodulatory Agents: A Real-Life Multicenter Analysis Open
In this study, as in previous similar studies, we could not see an increased survival trend in pPCL, which is observed in MM. New studies are needed for pPCL, which is likely to increase with new diagnostic criteria, based on current agent…
Features and Relapse/Refractory Disease Risk Factors of Patients with Acquired Thrombotic Thrombocytopenic Purpura in the Western Mediterranean Region of Turkey Open
The importance of parameters that predict and prevent relapse has increased in thrombotic thrombocytopenic purpura (TTP), where response and overall survival rates exceed 90% with current approaches. In this respect, we examined the clinic…
Single Apheresis Session on the 4th Day of Granulocyte Colony-Stimulating Factor Administration Seems Convenient to Collect Enough Peripheral Blood Stem Cells from Healthy Donors Open
Background: To minimize adverse events of peripheral blood stem cell (PBSC) collection in healthy donors, it is reasonable to limit the total dose of granulocyte colony-stimulating factor (G-CSF) and/or the number of apheresis days without…
Primary Thyroid Lymphoma: A Nationwide Retrospective Cohort Analysis of Survival and Determinant Factors Open
Purpose This study aims to analyze survival rates and determinant factors in patients diagnosed with primary thyroid lymphoma, a rare subtype of thyroid cancer. Methods We conducted a retrospective analysis of 57 primary thyroid lymphoma c…
View article: Prospective Real-World Outcomes of Acute Myeloid Leukemia
Prospective Real-World Outcomes of Acute Myeloid Leukemia Open
Background: It is evident that treatment outcomes improve with the clinical studies, in this study we aimed to investigate the demographics and treatment modalities of the acute myeloid leukemia (AML) patients in a large population-based c…
Clinical and Survival Outcomes in Patients with Supra-Diaphragmatic Vs İnfra-Diaphragmatic Diffuse Large B Cell Lymphoma Open
Erken evre diffüz büyük B hücreli lenfoma (DBBHL), tüm DBBHL olgularının yaklaşık %30'unu oluşturur. Bu çalışma, birinci basamak rituksimab, siklofosfamid, doksorubisin, vinkristin ve prednizon (R-CHOP) ile tedavi edilen erken evre DBBHL t…
Comparison the Clinical Features of Newly Diagnosed Multiple Myeloma Patients According to CD23 Expression Status Open
Introduction:The aim of the study was to evaluate the relationship between CD23 expression status and clinical features in multiple myeloma patients. Materials and methods:We retrospectively analyzed the data of 196 patients diagnosed with…
PB1961 THREE CHRONIC MYELOID LEUKEMIA CASES THAT PRESENTED LIKE ESSENTIAL THROMBOCYTHEMIA Open
Background: 2016 WHO classification divides myeloprolipherative neoplasms into bcr‐abl positive and bcr‐abl negative neoplasms, not only because of treatment difference also because of the heterogeneity of clinical presentations in Chronic…
Comment on: Type 1 cryoglobulinaemia leading to gangrene of the toes and ischaemic ulceration Open
I read with great interest the recent article by Siow et al (2018) regarding type 1 cryoglobulinaemia leading to gangrene of the toes and ischaemic ulceration. I would like to add some points. Type 1 cryoglobulinaemia is usually asymptomat…
Glucose-6 Phosphate Dehydrogenase Deficiency in A Geriatric Patient Open
An otherwise healthy 76 years old female patient presented to emergency department with acute fatigue, weakness and jaundice.She stated ingestion of roughly 1 kilograms of boiled fava beans 2 days prior.She had ingested both fresh and cook…
C-MYC and BCL2 translocation frequency in diffuse large B-cell lymphomas: A study of 97 patients. Open
We concluded that C-MYC and BCL2 may contribute to aggressive transformation, and more mechanism-based therapy should be explored. Targeted therapies involving these rearrangements and its associated pathways may change the fate of DLBCLs.…