Uwe Plessmann
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View article: Pathogenesis and Clinical Relevance of Diffuse Large B-Cell Lymphoma Proteogenotypes
Pathogenesis and Clinical Relevance of Diffuse Large B-Cell Lymphoma Proteogenotypes Open
Diffuse large B-cell lymphomas (DLBCL) are genetically and clinically heterogenous. Despite advances in the gene-expression and genomic characterization, the pathophysiology of high-risk DLBCL still remains incompletely understood. We repo…
View article: Proteomic mapping of atrial and ventricular heart tissue in patients with aortic valve stenosis
Proteomic mapping of atrial and ventricular heart tissue in patients with aortic valve stenosis Open
Aortic valve stenosis (AVS) is one of the most common valve diseases in the world. However, detailed biological understanding of the myocardial changes in AVS hearts on the proteome level is still lacking. Proteomic studies using high-reso…
View article: Additional file 6 of Proteogenomics analysis of CUG codon translation in the human pathogen Candida albicans
Additional file 6 of Proteogenomics analysis of CUG codon translation in the human pathogen Candida albicans Open
Additional file 6. Raw and additional data relevant to Figure 6.
View article: Additional file 2 of Proteogenomics analysis of CUG codon translation in the human pathogen Candida albicans
Additional file 2 of Proteogenomics analysis of CUG codon translation in the human pathogen Candida albicans Open
Additional file 2. Raw and additional data relevant to Figure 2.
View article: Additional file 4 of Proteogenomics analysis of CUG codon translation in the human pathogen Candida albicans
Additional file 4 of Proteogenomics analysis of CUG codon translation in the human pathogen Candida albicans Open
Additional file 4. Raw and additional data relevant to Figure 4.
View article: Extracellular MIF, but not its homologue D-DT, promotes fibroblast motility independently of its receptor complex CD74/CD44
Extracellular MIF, but not its homologue D-DT, promotes fibroblast motility independently of its receptor complex CD74/CD44 Open
Macrophage migration inhibitory factor (MIF) and its homologue D-dopachrome tautomerase (D-DT) are widely expressed pro-inflammatory cytokines with chemokine-like functions that coordinate a wide spectrum of biological activities, such as …
View article: Proteogenomics analysis of CUG codon translation in the human pathogen<i>Candida albicans</i>
Proteogenomics analysis of CUG codon translation in the human pathogen<i>Candida albicans</i> Open
Candida yeasts causing human infections are spread across the yeast phylum with Candida glabrata being related to Saccharomyces cerevisiae, Candida krusei grouping to Pichia spp. , and Candida albicans, Candida parapsilosis and Candida tro…
View article: Identification of new high affinity targets for Roquin based on structural conservation
Identification of new high affinity targets for Roquin based on structural conservation Open
Post-transcriptional gene regulation controls the amount of protein produced from a specific mRNA by altering both its decay and translation rates. Such regulation is primarily achieved by the interaction of trans-acting factors with cis-r…
View article: Comparative proteomics reveals a diagnostic signature for pulmonary head‐and‐neck cancer metastasis
Comparative proteomics reveals a diagnostic signature for pulmonary head‐and‐neck cancer metastasis Open
Patients with head-and-neck cancer can develop both lung metastasis and primary lung cancer during the course of their disease. Despite the clinical importance of discrimination, reliable diagnostic biomarkers are still lacking. Here, we h…
View article: Endogenous Stochastic Decoding of the CUG Codon by Competing Ser- and Leu-tRNAs in Ascoidea asiatica
Endogenous Stochastic Decoding of the CUG Codon by Competing Ser- and Leu-tRNAs in Ascoidea asiatica Open
Although the "universal" genetic code is now known not to be universal, and stop codons can have multiple meanings, one regularity remains, namely that for a given sense codon there is a unique translation. Examining CUG usage in yeasts th…
View article: Competing tRNA(CAG) in Ascoidea asiatica
Competing tRNA(CAG) in Ascoidea asiatica Open
These files contain supplementary data to the publication "Endogenous stochastic decoding of the CUG codon by competing Ser- and Leu-tRNAs in Ascoidea asiatica" by Stefanie Mühlhausen, Hans Dieter Schmitt, Kuan-Ting Pan, Uwe Plessmann, He…
View article: A novel nuclear genetic code alteration in yeasts and the evolution of codon reassignment in eukaryotes
A novel nuclear genetic code alteration in yeasts and the evolution of codon reassignment in eukaryotes Open
The genetic code is the cellular translation table for the conversion of nucleotide sequences into amino acid sequences. Changes to the meaning of sense codons would introduce errors into almost every translated message and are expected to…
View article: A novel nuclear genetic code alteration in yeasts and the evolution of codon reassignment in eukaryotes
A novel nuclear genetic code alteration in yeasts and the evolution of codon reassignment in eukaryotes Open
The genetic code is the universal cellular translation table to convert nucleotide into amino acid sequences. Changes to sense codons are expected to be highly detrimental. However, reassignments of single or multiple codons in mitochondri…