Baskar Venkidasamy
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View article: New-age frontiers in enhancing the mobility of cell-based biosensors using drone technology
New-age frontiers in enhancing the mobility of cell-based biosensors using drone technology Open
The application of cell-based biosensor technology has emerged as a cutting-edge tool in the domains of food safety, environmental monitoring and pharmaceutical research. These biosensors operate by detecting changes in cellular proliferat…
View article: Evaluation of a conserved glycoprotein precursor (GPC) derived, pan-Lassa fever T cell epitope-based vaccine candidate
Evaluation of a conserved glycoprotein precursor (GPC) derived, pan-Lassa fever T cell epitope-based vaccine candidate Open
Lassa fever (LF) is a viral zoonotic disease that can lead to fatal outcomes in some cases of human infection. Currently, no licensed vaccines are available to protect humans from this disease. Lassa virus (LASV) has a diverse genome compr…
View article: Different Derivatives of Plumbagin Analogue: Bioavailability and Their Toxicity Studies
Different Derivatives of Plumbagin Analogue: Bioavailability and Their Toxicity Studies Open
The roots of the Plumbago genus, specifically Plumbago zeylanica and related species, contain natural plumbagin. Because of its possible medicinal benefits, naphthoquinone has been the subject of several studies. Ongoing research aims to b…
View article: Plant‐Based Mycetoma Inhibitors Targeting the 50S Ribosomal Protein of <i>Nocardia brasiliensis</i> : In Silico Approach
Plant‐Based Mycetoma Inhibitors Targeting the 50S Ribosomal Protein of <i>Nocardia brasiliensis</i> : In Silico Approach Open
Mycetoma is a subcutaneous, potentially serious, and devastating chronic disease caused by aerobic actinomycetes (actinomycetoma) or fungi (eumycetoma). Nocardia species causes pulmonary, cutaneous, and subcutaneous human diseases, especia…
View article: Efficient Plant Growth-Promoting (PGP) Native <i>Actinomycetes</i>-Formulated Consortia Mode and Assessed Shelf Life Using Low-Cost Dynamic Media
Efficient Plant Growth-Promoting (PGP) Native <i>Actinomycetes</i>-Formulated Consortia Mode and Assessed Shelf Life Using Low-Cost Dynamic Media Open
Various Actinomycete isolates were collected from the microbial germplasm, including Streptomyces rameus KAC3 (PP550146), Streptomyces bangladeshensis KAC4 (PP177363), Streptomyces mutabilis KAC6 (PP177364), …
View article: Retraction notice to “Antibacterial activity of seed aqueous extract of Citrus limon (L.) mediated synthesis ZnO NPs: An impact on Zebrafish (Danio rerio) caudal fin development” [Heliyon 8 (2022) e10406]
Retraction notice to “Antibacterial activity of seed aqueous extract of Citrus limon (L.) mediated synthesis ZnO NPs: An impact on Zebrafish (Danio rerio) caudal fin development” [Heliyon 8 (2022) e10406] Open
[This retracts the article DOI: 10.1016/j.heliyon.2022.e10406.].
View article: Design, Synthesis, in Silico and in Vitro Evaluation of 3-Hydroxyflavone Derivatives Against Dengue Virus
Design, Synthesis, in Silico and in Vitro Evaluation of 3-Hydroxyflavone Derivatives Against Dengue Virus Open
View article: Reactive oxygen and nitrogen species in plant defense mechanisms
Reactive oxygen and nitrogen species in plant defense mechanisms Open
View article: Phyto-derived interferons: a promising frontier in antiviral therapy development
Phyto-derived interferons: a promising frontier in antiviral therapy development Open
View article: NUTRITIONAL AND THERAPEUTIC POTENTIAL OF BIOACTIVE COMPOUNDS FROM MELONS: A MINI REVIEW
NUTRITIONAL AND THERAPEUTIC POTENTIAL OF BIOACTIVE COMPOUNDS FROM MELONS: A MINI REVIEW Open
Fruit wastes are one of the major sources of municipal waste, however they are a source of bioactive useful compounds which possess numerous health benefits. The fruit processing industry generates 10-60% waste or by-products in solid (pee…
View article: In vivo biological screening of extract and bioactive compound from Ficus benghalensis L. and their in silico molecular docking analysis
In vivo biological screening of extract and bioactive compound from Ficus benghalensis L. and their in silico molecular docking analysis Open
BACKGROUND: Ficus benghalensis has been used by local health care practitioners to treat pain, inflammation, rheumatism, and other health issues. OBJECTIVE: In this study, the crude extract and diverse fractions, along with the isolated co…
View article: Network pharmacology: an efficient but underutilized approach in oral, head and neck cancer therapy—a review
Network pharmacology: an efficient but underutilized approach in oral, head and neck cancer therapy—a review Open
The application of network pharmacology (NP) has advanced our understanding of the complex molecular mechanisms underlying diseases, including neck, head, and oral cancers, as well as thyroid carcinoma. This review aimed to explore the the…
View article: Vanillic Acid Nanocomposite: Synthesis, Characterization Analysis, Antimicrobial, and Anticancer Potentials
Vanillic Acid Nanocomposite: Synthesis, Characterization Analysis, Antimicrobial, and Anticancer Potentials Open
Recently, nanoparticles have received considerable attention owing to their efficiency in overcoming the limitations of traditional chemotherapeutic drugs. In our study, we synthesized a vanillic acid nanocomposite using both chitosan and …
View article: Prospective roles of sirtuin 1 (SIRT1) in oral cancer therapy
Prospective roles of sirtuin 1 (SIRT1) in oral cancer therapy Open
• SIRT1 is a promising target in oral cancer as it regulates proliferation, apoptosis, and DNA repair. • SIRT1 acts as a tumor suppressor, and low SIRT1 levels have been linked to lymphovascular permeation. • SIRT1 is involved in the regul…
View article: Nano-based biofuel production from low-cost lignocellulose biomass: environmental sustainability and economic approach
Nano-based biofuel production from low-cost lignocellulose biomass: environmental sustainability and economic approach Open
The use of nanomaterials in biofuel production from lignocellulosic biomass offers a promising approach to simultaneously address environmental sustainability and economic viability. This review provides an overview of the environmental an…
View article: Nanotechnology Approaches for the Remediation of Agricultural Polluted Soils
Nanotechnology Approaches for the Remediation of Agricultural Polluted Soils Open
Soil pollution from various anthropogenic and natural activities poses a significant threat to the environment and human health. This study explored the sources and types of soil pollution and emphasized the need for innovative remediation…
View article: Quercetin, a natural antioxidant compound for the treatment of oral cancer therapy
Quercetin, a natural antioxidant compound for the treatment of oral cancer therapy Open
• Quercetin is a flavonoid is found in fruits and vegetables and also exerts potential antioxidant activity. • Quercetin's anticancer effects are due to free radical scavenging activity and inhibit the cancer cell proliferation through cel…
View article: Theragnostic perspectives of Mucin 1 for oral cancer
Theragnostic perspectives of Mucin 1 for oral cancer Open
• Mucin are glycoproteins, major functions are cell growth, cell differentiation, cell signaling. • Mucins are widely used in the treatment of variety of cancer and other diseases. • Mucin acts as a marker to detect cancer. • MUC1 serves a…
View article: Potential roles of genistein, a phytoestrogen, in oral cancer treatment
Potential roles of genistein, a phytoestrogen, in oral cancer treatment Open
• Genistein is an isoflavone exists primarily in soybean and soy products. • It's a phytoestrogen exerts improved anticancer activity. • Genistein induce apoptosis, cell cycle modulation and antiangiogenic activity. • It showed increased a…
View article: Sulforaphane: Potent antioxidant molecule for oral cancer treatment
Sulforaphane: Potent antioxidant molecule for oral cancer treatment Open
• Sulforaphane (SF) a potent antioxidant molecule from crucifer plants. • SF a prevalent inducer of NRF2 pathway and carcinogen detoxifying enzymes. • SF impacts in oral and head and neck cancer was discussed. • Nanoformulation of phytocom…
View article: Probiotic bacteria therapy for oral cancer treatment: An emerging approach on bacteriocin and exopolysaccharides
Probiotic bacteria therapy for oral cancer treatment: An emerging approach on bacteriocin and exopolysaccharides Open
• Probiotic therapy for treatment of oral cancer. • Therapeutic intervention of oral cancer by bacteriocin and exopolysaccharide. • Mechanism of molecular mode of action of probiotics and its products for the inhibition of cancer cells.
View article: Homology modeling and protein-protein interaction studies of GAPDH from Helopeltis theivora and chitinase from Pseudomonas fluorescens to control infection in tea [Camellia sinensis (L.) O. Kuntze] plants
Homology modeling and protein-protein interaction studies of GAPDH from Helopeltis theivora and chitinase from Pseudomonas fluorescens to control infection in tea [Camellia sinensis (L.) O. Kuntze] plants Open
Tea [Camellia sinensis (L.) O. Kuntze] is an important crop cultivated in all over the world. The main problem in tea cultivation is the attack by a bug called Helopeltis theivora. Many different strategies, such as the use of pesticides a…
View article: Evaluation of oyster mushroom (<i>Pleurotus ostreatus</i>)-derived anthraquinone on the induction of apoptosis and suppression of MMP-2 and MMP-9 expression in breast cancer cells
Evaluation of oyster mushroom (<i>Pleurotus ostreatus</i>)-derived anthraquinone on the induction of apoptosis and suppression of MMP-2 and MMP-9 expression in breast cancer cells Open
Introduction: Breast cancer results from tissue degradation caused by environmental and genetic factors that affect cells in the body. Matrix metalloproteinases, such as MMP-2 and MMP-9, are considered potential putative markers for…
View article: Comprehensive study on the differential extraction and comparison of bioactive health potential of the Broccoli (<i>Brassica oleracea</i>)
Comprehensive study on the differential extraction and comparison of bioactive health potential of the Broccoli (<i>Brassica oleracea</i>) Open
Introduction: Broccoli is a cruciferous vegetable that has been shown to have numerous potential therapeutic benefits because of its bioactive compounds. Methods: In this study, we compared the bioactive efficacy of cooked an…
View article: Deciphering the Anticancer Arsenal of <i>Piper longum</i>: Network Pharmacology and Molecular Docking Unveil Phytochemical Targets Against Lung Cancer
Deciphering the Anticancer Arsenal of <i>Piper longum</i>: Network Pharmacology and Molecular Docking Unveil Phytochemical Targets Against Lung Cancer Open
Introduction: Lung cancer, characterized by uncontrolled cellular proliferation within the lung tissues, is the predominant cause of cancer-related fatalities worldwide. The traditional medicinal herb Piper longum has emerged…
View article: Understanding Macroalgae: A Comprehensive Exploration of Nutraceutical, Pharmaceutical, and Omics Dimensions
Understanding Macroalgae: A Comprehensive Exploration of Nutraceutical, Pharmaceutical, and Omics Dimensions Open
Driven by a surge in global interest in natural products, macroalgae or seaweed, has emerged as a prime source for nutraceuticals and pharmaceutical applications. Characterized by remarkable genetic diversity and a crucial role in marine e…
View article: Alpinia galanga bioactive constituents as multi-target inhibitors of SARS-CoV-2 proteins: A molecular docking, molecular simulation and ADMET analysis
Alpinia galanga bioactive constituents as multi-target inhibitors of SARS-CoV-2 proteins: A molecular docking, molecular simulation and ADMET analysis Open
View article: Gelatin/Nanofibrin bioactive scaffold prepared with enhanced biocompatibility for skin tissue regeneration
Gelatin/Nanofibrin bioactive scaffold prepared with enhanced biocompatibility for skin tissue regeneration Open
This research study was to develop a nano bioactive scaffold (NBAS) using gelatins (Gel), nanofibrin (Nano-FB), and glycerol (Gly) by film casting method for potential use in skin tissue engineering. The developed NBAS were characterized f…
View article: Functional role of microRNA in the regulation of biotic and abiotic stress in agronomic plants
Functional role of microRNA in the regulation of biotic and abiotic stress in agronomic plants Open
The increasing demand for food is the result of an increasing population. It is crucial to enhance crop yield for sustainable production. Recently, microRNAs (miRNAs) have gained importance because of their involvement in crop productivity…
View article: SDF in radiation-induced caries
SDF in radiation-induced caries Open