Explanipedia

PHOTON ISOEFFECTIVE MICRODOSIMETRIC DOSE MODEL FOR GLIOBLASTOMA MULTIFORME IN BORON NEUTRON CAPTURE THERAPY Open

Agustina Mariana Portu, Cristina Pezzi, V. Vercesi, Silva Bortolussi, Sara J. González · 2025

Thermal neutron cross sections of aluminum and magnesium fluorides and quantum kinetic energy of fluorine Open

Margherita Simoni, Setareh Fatemi, Lorenzo Airoldi, Silva Bortolussi, Mattia Gaboardi , et al. · 2025

We provide the modeling and experimental validation of thermal neutron cross sections, including scattering and absorption contributions, of aluminum fluoride and magnesium fluoride, as well as MgF2–AlF3 and AlF3–LiF mixtures, in the neutr…

Cellular irradiation with 583 keV protons at the CIRCE tandem accelerator: adosimetric and radiobiological investigation for BNCT applications Open

Rosa Sica, D. Pistone, Laura Bagnale, Emilia Formicola, Valerio Cosimo Elia , et al. · 2025

Boron Neutron Capture Therapy (BNCT) exploits the 10 B(n, α ) 7 Li reaction to deliver localized high-LET radiation to tumour cells enriched with 10 B-labelled drugs. However, other neutron-induced reactions, including 14 N(n,p) 14 C, also…

Incorporation of dose-rate effects into the BIANCA biophysical model and application for space radiation risk assessment Open

Ezgi Canay, Mario Pietro Carante, A.M. Casali, E. Bernardini, Daniele Dondi , et al. · 2025

Dosimetric comparison of the BNCT treatment planning performances when using a nnU-NET to automatically segment Glioblastoma Multiforme Open

Cristina Pezzi, Francesco Morosato, Barbara Marcaccio, Silva Bortolussi, Ricardo Luis Ramos , et al. · 2025

Radiation protection assessment of patient activation and dosimetry in Boron Neutron Capture Therapy Open

Giovanni Garini, Chiara Magni, Ian Postuma, Setareh Fatemi, Ricardo Luis Ramos , et al. · 2025

Towards an adequate description of the dose‐response relationship in BNCT of glioblastoma multiforme Open

Barbara Marcaccio, Marco Crepaldi, Ian Postuma, Erica Simeone, Claretta Guidi , et al. · 2025

Background Boron Neutron Capture Therapy (BNCT) is a binary radiotherapy based on the intravenous administration of a borated drug to the patient and the subsequent irradiation with a low‐energy neutron beam. The borated formulation accumu…

A GATE Monte Carlo study on ICRP110 phantoms for BNCT dosimetry evaluation Open

D. Pistone, Silva Bortolussi, Setareh Fatemi, Barbara Marcaccio, Laura Bagnale , et al. · 2025

Boron Neutron Capture Therapy (BNCT) is attracting renewed attention due to advancements in compact proton accelerators for the production of neutron beams, and new BNCT facilities are being planned all around the world. A key aspect in BN…

A new boron-doped gas microdosimeter for clinical Boron Neutron Capture Therapy Open

A. Della Selva, Anna Bianchi, M. Rossignoli, Silva Bortolussi, Ian Postuma , et al. · 2025

The Next Generation EU project ANTHEM (AdvaNced Technologies for Human-centrEd Medicine) aims at building a new accelerator-based BNCT facility in Caserta, Italy. In this framework, a new miniaturized Tissue-Equivalent Proportional Counter…

Evaluation of patient activation and dosimetry after Boron Neutron Capture Therapy Open

Giovanni Garini, Chiara Magni, Ian Postuma, Setareh Fatemi, Ricardo Luis Ramos , et al. · 2025

Boron Neutron Capture Therapy (BNCT) is a form of radiotherapy based on the irradiation of the tumour with a low energy neutron beam, after the administration of a selective drug enriched in boron-10. The therapy exploits the high cross se…

Evaluation of Patient Activation and Dosimetry after Boron Neutron Capture Therapy Open

Silva Bortolussi, Giovanni Garini, Chiara Magni, Ian Postuma, Setareh Fatemi , et al. · 2025

Radiation exposure of astronauts following an intense solar particle event: analysis and comparison of doses in male and female voxel phantoms Open

Ricardo Luis Ramos, E. Bernardini, Mario Pietro Carante, A. Ferrari, P. Sala , et al. · 2024

According to NASA’s plans, a human travel to the Moon is planned by the end of 2025 with the Artemis II mission, and humans should land on the Moon again in 2026. Exposure to space radiation is one of the main risks for the crew members; w…

MICRODOSIMETRY FOR BNCT: FIRST TESTS IN REALISTIC NEUTRON FIELDS Open

A. Della Selva, Anna Bianchi, Luca Bellan, Ian Postuma, Silva Bortolussi , et al. · 2024

FIRST COMPARISON AND COMBINATION OF BNCT AND CIRT DOSIMETRY IN A HEAD AND NECK TUMOR USING ISOEFFECTIVE DOSE MODEL. Open

Ian Postuma, Chiara Magni, Barbara Marcaccio, Setareh Fatemi, V. Vercesi , et al. · 2024

A method to predict space radiation biological effectiveness for non-cancer effects following intense Solar Particle Events Open

Ricardo Luis Ramos, Mario Pietro Carante, E. Bernardini, A. Ferrari, P. Sala , et al. · 2024

In addition to the continuous exposure to cosmic rays, astronauts in space are occasionally exposed to Solar Particle Events (SPE), which involve less energetic particles but can deliver much higher doses. The latter can exceed several Gy …

Using the photon isoeffective dose formalism to compare and combine BNCT and CIRT in a head and neck tumour Open

Ian Postuma, Chiara Magni, Barbara Marcaccio, Setareh Fatemi, V. Vercesi , et al. · 2024

Boron Neutron Capture Therapy (BNCT) is a radiotherapy technique based on the enrichment of tumour cells with suitable 10-boron concentration and on subsequent neutron irradiation. Low-energy neutron irradiation produces a localized deposi…

AISHa: an ECRIS for nuclear-physics, new clinical protocols and material experiments Open

L. Celona, O. Leonardi, G. Castro, S. Gammino, L. Neri , et al. · 2024

The Advanced Ion Source for Hadrontherapy (AISHa) is an ECR ion source operating at 18 GHz, developed with the aim to produce multiply charged ion beams with low ripple, high stability and reproducibility. Due to its unique peculiarity, it…

Using the photon isoeffective dose formalism to compare and combine BNCT and carbon-ion radiotherapy: an example of head and neck tumour Open

Ian Postuma, Chiara Magni, Barbara Marcaccio, Setareh Fatemi, V. Vercesi , et al. · 2023

Boron Neutron Capture Therapy (BNCT) is a radiotherapy technique based on the enrichment of tumour cells with suitable10-boron concentration and on subsequent neutron irradiation. Low-energy neutron irradiation produces a localized deposit…

A Mission to Mars: Prediction of GCR Doses and Comparison with Astronaut Dose Limits Open

Ricardo Luis Ramos, Mario Pietro Carante, A. Ferrari, P. Sala, V. Vercesi , et al. · 2023

Long-term human space missions such as a future journey to Mars could be characterized by several hazards, among which radiation is one the highest-priority problems for astronaut health. In this work, exploiting a pre-existing interface b…

Space radiation damage: calculation of astronauts‘ doses and comparison with dose limits Open

Ricardo Luis Ramos, Mario Pietro Carante, A. Ferrari, P. Sala, V. Vercesi , et al. · 2023

Development of the ACSpect neutron spectrometer: Technological advance and response against an accelerator-based neutron beam Open

Gabriele Parisi, A. Pola, D. Bortot, D. Mazzucconi, Giovanni D’Angelo , et al. · 2022

Advances in neutron-based radiation therapies such as Boron Neutron Capture Therapy (BNCT) pushes towards the development of new neutron spectrometers, whose key features are to be their practicability, reliability, energy resolution and d…

Extension of the BIANCA biophysical model up to Fe-ions and applications for space radiation research Open

Ricardo Luis Ramos, A. Embriaco, Mario Pietro Carante, A. Ferrari, P. Sala , et al. · 2022

BIANCA (BIophysical ANalysis of Cell death and chromosome Aberrations) is a biophysical model, implemented as a Monte Carlo code, which simulates the induction of chromosome aberrations and cell death by different monochromatic ion beams (…

Healthy Tissue Damage Following Cancer Ion Therapy: A Radiobiological Database Predicting Lymphocyte Chromosome Aberrations Based on the BIANCA Biophysical Model Open

A. Embriaco, Ricardo Luis Ramos, Mario Pietro Carante, A. Ferrari, P. Sala , et al. · 2021

Chromosome aberrations are widely considered among the best biomarkers of radiation health risk due to their relationship with late cancer incidence. In particular, aberrations in peripheral blood lymphocytes (PBL) can be regarded as indic…

A Novel Approach to Design and Evaluate BNCT Neutron Beams Combining Physical, Radiobiological, and Dosimetric Figures of Merit Open

Ian Postuma, Sara J. González, María S. Herrera, L. Provenzano, M. Ferrarini , et al. · 2021

(1) Background:The quality of neutron beams for Boron Neutron Capture Therapy (BNCT) is currently defined by its physical characteristics in air. Recommendations exist to define whether a designed beam is useful for clinical treatment. Thi…

Evaluating the Therapeutic Potential and the Suitability of Neutron Beams Designed for Clinical BNCT Open

Ian Postuma, Sara J. González, María S. Herrera, L. Provenzano, M. Ferrarini , et al. · 2020

The standard of neutron beam quality for Boron Neutron Capture Therapy (BNCT) of deep-seated tumours is currently deﬁned by its physical characteristics in air: the epithermal neutron ﬂux, the ratio of thermal and epithermal neutron ﬂux, t…

Design of a BNCT irradiation room based on proton accelerator and beryllium target Open

Chiara Magni, Ian Postuma, M. Ferrarini, Nicoletta Protti, Setareh Fatemi , et al. · 2020

Old and new observables for αs from e+e- to hadrons Open

G. Somogyi, Ádám Kardos, S. Kluth, Zoltán László Trócsányi, Zoltán Tulipánt , et al. · 2020

Design of a hardware track finder (Fast Tracker) for the ATLAS trigger Open

V. Cavaliere, J. Adelman, P. Albicocco, J. Alison, L. S. Ancu , et al. · 2016

The use of tracking information at the trigger level in the LHC Run II period is crucial for the trigger an data acquisition (TDAQ) system and will be even more so as contemporary collisions that occur at every bunch crossing will increase…

The ATLAS fast tracker processor design Open

G. Volpi, J. Adelman, P. Albicocco, John Alison, Lucian Stefan Ancu , et al. · 2015

The extended use of tracking information at the trigger level in the LHC is crucial for the trigger and data acquisition (TDAQ) system to fulfill its task. Precise and fast tracking is important to identify specific decay products of the H…

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