Mykhailo Gonchar
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View article: A thermosensitive α-amino acid hydrogel layer deposited on an electrode surface: Actuator and sensor performance
A thermosensitive α-amino acid hydrogel layer deposited on an electrode surface: Actuator and sensor performance Open
The aim of this work was the development of a novel stimuli-responsive hydrogel layer containing an acryloyl derivative of an α-amino acid and its electroanalytical characterization. The electroactive, electrosensitive, and thermosensitive…
View article: Biofuel Cells Based on Oxidoreductases and Electroactive Nanomaterials: Development and Characterization
Biofuel Cells Based on Oxidoreductases and Electroactive Nanomaterials: Development and Characterization Open
Amperometric biosensors (ABSs) and enzymatic biofuel cells (BFCs) share several fundamental principles in their functionality, despite serving different primary purposes. Both devices rely on biorecognition, redox reactions, electron trans…
View article: Copper Hexacyanoferrates Obtained via Flavocytochrome b2 Assistance: Characterization and Application
Copper Hexacyanoferrates Obtained via Flavocytochrome b2 Assistance: Characterization and Application Open
Artificial enzymes or nanozymes (NZs) are gaining significant attention in biotechnology due to their stability and cost-effectiveness. NZs can offer several advantages over natural enzymes, such as enhanced stability under harsh condition…
View article: Peroxidase-like Nanoparticles of Noble Metals Stimulate Increasing Sensitivity of Flavocytochrome b2-Based L-Lactate Biosensors
Peroxidase-like Nanoparticles of Noble Metals Stimulate Increasing Sensitivity of Flavocytochrome b2-Based L-Lactate Biosensors Open
We report the development of amperometric biosensors (ABSs) employing flavocytochrome b2 (Fcb2) coupled with nanoparticles (NPs) of noble metals on graphite electrode (GE) surfaces. Each NPs/GE configuration was evaluated for its ability t…
View article: Enzymatically Triggered Drug Release from Microgels Controlled by Glucose Concentration
Enzymatically Triggered Drug Release from Microgels Controlled by Glucose Concentration Open
This study aims to design microgels for controlled drug release via enzymatically generated pH changes in the presence of glucose. Modern medicine is focused on developing smart delivery systems with controlled release capabilities. In res…
View article: Nanoparticles of prussian blue analogues as peroxidase mimetics for nanozyme – oxidase – based biosensors
Nanoparticles of prussian blue analogues as peroxidase mimetics for nanozyme – oxidase – based biosensors Open
Keywords: Prussian blue analogues, nanozymes, artificial peroxidase, glucose oxidase, galactose oxidase, amperometric biosensor
View article: Highly sensitive amperometric sensors based on laccase-mimetic nanozymes for the detection of dopamine
Highly sensitive amperometric sensors based on laccase-mimetic nanozymes for the detection of dopamine Open
Novel nanozymes possesses the ability to mimic laccase. New amperometric biosensor for determination of dopamine was constructed.
View article: Ammonium nanochelators in conjunction with arginine-specific enzymes in amperometric biosensors for arginine assay
Ammonium nanochelators in conjunction with arginine-specific enzymes in amperometric biosensors for arginine assay Open
Amino acid L-arginine (Arg), usually presented in food products and biological liquids, can serve both as a useful indicator of food quality and an important biomarker in medicine. The biosensors based on Arg-selective enzymes are the most…
View article: Effect of Aromatic Rings in AESO-VDM Biopolymers on the Local Free Volume and Diffusion Properties of Polymer Matrix
Effect of Aromatic Rings in AESO-VDM Biopolymers on the Local Free Volume and Diffusion Properties of Polymer Matrix Open
In this work, the influence of aromatic rings on the local free volume of cured mixtures of acrylate epoxidized soybean oil (AESO) and vanillin dimethacrylate (VDM) was investigated. Cross-linking took place under the influence of UV light…
View article: The Peroxidase-like Nanocomposites as Hydrogen Peroxide-Sensitive Elements in Cholesterol Oxidase-Based Biosensors for Cholesterol Assay
The Peroxidase-like Nanocomposites as Hydrogen Peroxide-Sensitive Elements in Cholesterol Oxidase-Based Biosensors for Cholesterol Assay Open
Catalytically active nanomaterials, in particular, nanozymes, are promising candidates for applications in biosensors due to their excellent catalytic activity, stability and cost-effective preparation. Nanozymes with peroxidase-like activ…
View article: Flavocytochrome b2-Mediated Electroactive Nanoparticles for Developing Amperometric L-Lactate Biosensors
Flavocytochrome b2-Mediated Electroactive Nanoparticles for Developing Amperometric L-Lactate Biosensors Open
L-Lactate is an indicator of food quality, so its monitoring is essential. Enzymes of L-Lactate metabolism are promising tools for this aim. We describe here some highly sensitive biosensors for L-Lactate determination which were developed…
View article: Lactic acid as a systemic product and biomarker of physical load
Lactic acid as a systemic product and biomarker of physical load Open
This paper presents an up-to-date review of research data on the specific features of lactic acid metabolism and its role as an effector of vital regulatory mechanisms. Lactic acid is an alpha-hydroxy monocarboxylic acid. Physical loads of…
View article: Prussian blue and its analogues as artificial enzymes and prospects for their application
Prussian blue and its analogues as artificial enzymes and prospects for their application Open
In recent years, Prussian blue nanoparticles (PB-NPs) and theire analogues, that exhibit an increased catalytic activity, have attracted considerable attention in nanotechnology. Such nanoparticles are regarded as an alternative to natural…
View article: Biosensor Based on Peroxidase-Mimetic Nanozyme and Lactate Oxidase for Accurate L-Lactate Analysis in Beverages
Biosensor Based on Peroxidase-Mimetic Nanozyme and Lactate Oxidase for Accurate L-Lactate Analysis in Beverages Open
Precision analysis of the key biological metabolites such as L-lactate has great practical importance for many technological processes in food technology, including beverage production. Here we describe a new, highly selective, and sensiti…
View article: UV-Cured Green Polymers for Biosensorics: Correlation of Operational Parameters of Highly Sensitive Biosensors with Nano-Volumes and Adsorption Properties
UV-Cured Green Polymers for Biosensorics: Correlation of Operational Parameters of Highly Sensitive Biosensors with Nano-Volumes and Adsorption Properties Open
The investigated polymeric matrixes consisted of epoxidized linseed oil (ELO), acrylated epoxidized soybean oil (AESO), trimethylolpropane triglycidyl ether (RD1), vanillin dimethacrylate (VDM), triarylsulfonium hexafluorophosphate salts (…
View article: Nanomaterials as Redox Mediators in Laccase-Based Amperometric Biosensors for Catechol Assay
Nanomaterials as Redox Mediators in Laccase-Based Amperometric Biosensors for Catechol Assay Open
Laccase is a copper-containing enzyme that does not require hydrogen peroxide as a co-substrate or additional cofactors for an enzymatic reaction. Nanomaterials of various chemical structures are usually applied to the construction of enzy…
View article: A new spectrophotometric method analysis of adrenaline in pharmaceuticals based on laccase-like nanozymes
A new spectrophotometric method analysis of adrenaline in pharmaceuticals based on laccase-like nanozymes Open
Nanozymes, which have high enzyme-like activity of natural enzymes, are very promising for analytical purposes, in particular, for the development of methods for sensitive, quantitative detection of practically important analytes – biomark…
View article: Highly Porous 3D Gold Enhances Sensitivity of Amperometric Biosensors Based on Oxidases and CuCe Nanoparticles
Highly Porous 3D Gold Enhances Sensitivity of Amperometric Biosensors Based on Oxidases and CuCe Nanoparticles Open
Metallic nanoparticles potentially have wide practical applications in various fields of science and industry. In biosensorics, they usually act as catalysts or nanozymes (NZs) and as mediators of electron transfer. We describe here the de…
View article: Highly Sensitive Amperometric Biosensors Based on Oxidases and CuCe Nanoparticles Coupled with Porous Gold
Highly Sensitive Amperometric Biosensors Based on Oxidases and CuCe Nanoparticles Coupled with Porous Gold Open
Metallic nanoparticles are usually applied in biosensors as catalysts and/or mediators of electron transfer. We describe the development of amperometric biosensors (ABSs) based on oxidases and nanoparticles of CuCe (nCuCe). nCuCe, being an…
View article: Reusable alcohol oxidase–nPtCu/alginate beads for highly sensitive ethanol assay in beverages
Reusable alcohol oxidase–nPtCu/alginate beads for highly sensitive ethanol assay in beverages Open
Novel colorimetric method based on alginate beads encapsulated with nPtCu and alcohol oxidase have been developed and optimized.
View article: Nanozymes with reductase-like activities: antioxidant properties and electrochemical behavior
Nanozymes with reductase-like activities: antioxidant properties and electrochemical behavior Open
Novel Zn/Cd/Cu bd nanozymes possesses the ability to mimic coenzyme-dependent selenite reductase. A new amperometric biosensor for determination of selenite was constructed.
View article: Highly Sensitive Amperometric Sensor Based on Laccase-Mimicking Metal-Based Hybrid Nanozymes for Adrenaline Analysis in Pharmaceuticals
Highly Sensitive Amperometric Sensor Based on Laccase-Mimicking Metal-Based Hybrid Nanozymes for Adrenaline Analysis in Pharmaceuticals Open
Nanozymes are nanomaterials which exhibit artificial enzymatic activities and are considered as alternatives to natural enzymes. They are characterized by good catalytic activity and high stability, as well as ease and low cost of preparat…
View article: Amperometric Biosensors for L-Arginine Determination Based on L-Arginine Oxidase and Peroxidase-Like Nanozymes
Amperometric Biosensors for L-Arginine Determination Based on L-Arginine Oxidase and Peroxidase-Like Nanozymes Open
There are limited data on amperometric biosensors (ABSs) for L-arginine (Arg) determination based on oxidases that produce hydrogen peroxide (H2O2) as a byproduct of enzymatic reaction, and artificial peroxidases (POs) for decomposition of…
View article: “Green” Prussian Blue Analogues as Peroxidase Mimetics for Amperometric Sensing and Biosensing
“Green” Prussian Blue Analogues as Peroxidase Mimetics for Amperometric Sensing and Biosensing Open
Prussian blue analogs (PBAs) are well-known artificial enzymes with peroxidase (PO)-like activity. PBAs have a high potential for applications in scientific investigations, industry, ecology and medicine. Being stable and both catalyticall…
View article: Peroxidase-Like Metal-Based Nanozymes: Synthesis, Catalytic Properties, and Analytical Application
Peroxidase-Like Metal-Based Nanozymes: Synthesis, Catalytic Properties, and Analytical Application Open
Nanozymes (NZs) are nanostructured artificial enzymes that mimic catalytic properties of natural enzymes. The NZs have essential advantages over natural enzymes, namely low preparation costs, stability, high surface area, self-assembling c…
View article: “Green” Nanozymes: Synthesis, Characterization, and Application in Amperometric (Bio)sensors
“Green” Nanozymes: Synthesis, Characterization, and Application in Amperometric (Bio)sensors Open
Nanozymes (NZs) are catalytically active nanomaterials that have enzyme-like activity but possess increased stability and greater availability due to the fact of their simpler preparation technologies. Nanozymes as nanoscale artificial enz…
View article: Synthesis, Catalytic Properties and Application in Biosensorics of Nanozymes and Electronanocatalysts: A Review
Synthesis, Catalytic Properties and Application in Biosensorics of Nanozymes and Electronanocatalysts: A Review Open
The current review is devoted to nanozymes, i.e., nanostructured artificial enzymes which mimic the catalytic properties of natural enzymes. Use of the term “nanozyme” in the literature as indicating an enzyme is not always justified. For …
View article: Controlling the Network Properties of Polymer Matrices for Improvement of Amperometric Enzyme Biosensors: Contribution of Positron Annihilation
Controlling the Network Properties of Polymer Matrices for Improvement of Amperometric Enzyme Biosensors: Contribution of Positron Annihilation Open
Recent results obtained by studies on the network properties using positron annihilation lifetime spectroscopy and swelling measurements in the ureasil-based and photocross-linked polymer matrices are compared.Common features observed are …