Explanipedia

Effect of Aficamten Compared With Metoprolol on Echocardiographic Measures in Symptomatic Obstructive Hypertrophic Cardiomyopathy Open

Sheila M. Hegde, Xiaowen Wang, Pablo García‐Pavía, Stoyan Getchevski, Ahmad Masri , et al. · 2025

Factors affecting surgical outcomes in cervical spondylotic myelopathy Open

Ajith Nair, Tinu Ravi Abraham, Alekhya Erubothu · 2025

Background: Cervical spondylotic myelopathy (CSM) is the most common cause of spinal cord dysfunction in adults over 40 years. It is often progressive, and delayed diagnosis may result in irreversible disability. Surgical decompression is …

Kidney Function Trajectories With Mechanical Circulatory Support Open

Carl P. Walther, Harveen K. Lamba, Ajith Nair, Andrew B. Civitello, Nandan K. Mondal , et al. · 2025

The curious case of a paraspinal mass Open

Ajith Nair, Tinu Ravi Abraham, Alekhya Erubothu · 2025

Chordomas are rare, slow-growing malignant neoplasms arising from embryonic notochord remnants, most commonly found in the sacrococcygeal region and skull base. Cervical chordomas are exceptionally rare, accounting for only 6% of cases. We…

Construct and Predictive Validity of the Kansas City Cardiomyopathy Questionnaire in Adult Congenital Heart Disease Open

Ryan Byrne, Ajith Nair, Stephen J. Dolgner, Swati Choudhry, Edward Hickey , et al. · 2025

Localized GLP1 receptor pre-internalization directs pancreatic alpha cell to beta cell communication Open

Jenny Tong, Charlotte Frazer-Morris, Ali H. Shilleh, Katrina Viloria, Anne de Bray , et al. · 2025

Pancreatic alpha cells modulate beta cell function in a paracrine manner through the release of glucagon. However, the detailed molecular architecture underlying alpha-to-beta cell regulation remains poorly characterized. Here, we show tha…

Cervical spondylodiscitis caused by Aspergillus in a non-immunocompromised patient: a case report Open

Ajith Nair, Tinu Ravi Abraham, Alekhya Erubothu · 2025

Spondylodiscitis caused by Aspergillus spp. is a rare but serious infection, making it particularly challenging to diagnose and manage. We report a case of a 53-year-old man presenting with neck pain and progressive quadriparesis. Neurolog…

AI Resume Analyzer: Smart Resume Evaluation and Enhancement Open

S.K. Das, Ajith Nair, Pattela Aneesh · 2025

This paper presents an AI-driven resume analyzer designed to streamline and enhance the job candidate assessment process. The system utilizes Natural Language Processing (NLP) techniques and machine learning algorithms to process and evalu…

Aficamten vs Metoprolol for Obstructive Hypertrophic Cardiomyopathy Open

Pablo García‐Pavía, Ozlem Bilen, Melissa Burroughs, Juan Pablo Costabel, Edileide de Barros Correia , et al. · 2025

Beta-blockers and nondihydropyridine calcium-channel blockers have been standard-of-care (SOC) medications for patients with symptomatic obstructive hypertrophic cardiomyopathy (oHCM), even though these agents do not directly affect the un…

Telehealth as a Substitute for a Usual Source of Care for Prescription Medications Open

David Shilane, Ajith Nair · 2025

This study investigates how effectively telehealth utilization (THU) can substitute for a usual source of care (USC) for taking prescription medication using data from the 2020-2022 National Health Interview Survey. We analyzed data for 69…

A Temporal Analysis of Bankruptcy Prediction Models: Logistic Regression vs. Altman Z-Score Open

Ajith Nair · 2025

Development of an Application-Based Digital Health Navigator for Perioperative Breast Surgery Patients Open

Matthew J. Piotrowski, Ajith Nair, Scott K. Alpard, Cristina M. Checka · 2025

The uses of right heart catheterization in cardio-pulmonary disease: State-of-the-art Open

Bhavesh B. Katbamna, Lingling Wu, Mario Rodríguez, Phillip King, Joel D. Schilling , et al. · 2024

Long term safety and outcomes after atrial shunting for heart failure with preserved or mildly reduced ejection fraction: 5-year and 3-year follow-up in the REDUCE LAP-HF I and II trials Open

Sheldon E. Litwin, Jan Komtebedde, Barry A. Borlaug, David M. Kaye, Gerd Hasenfuβ , et al. · 2024

Heart Transplantation in Young Adults: Comparison of Demographics and Outcomes at Pediatric and Adult Centers Following The 2018 Heart Allocation Policy Change Open

E.M. Kalb, S. Choudhry, Junho Cho, I. Adachi, Chris Broda , et al. · 2024

Predictors and Impact of Prolonged Vasoplegia After Continuous-Flow Left Ventricular Assist Device Implantation Open

Harveen K. Lamba, Mary Kim, Meng Li, Andrew B. Civitello, Ajith Nair , et al. · 2024

Compared with vasoplegia overall, prolonged vasoplegia was associated with worse survival after CF-LVAD implantation. Treatment to avoid or minimize progression to prolonged vasoplegia may be warranted.

An incidental finding of hypertrophic obstructive cardiomyopathy with an AV block Open

Zehra Aqeel Nizami, Ajith Nair, Rami Dhillon · 2024

Clinico-etiological profile of children with aplastic anaemia: A hospital-based, retrospective observational study Open

Chandra M. Kumar, Arnab Ghorui, Ajith Nair · 2024

Clinical Predictors and Outcomes After Left Ventricular Assist Device Implantation and Tracheostomy Open

Harveen K. Lamba, Lucy D. Hart, Qianzi Zhang, Jackquelin M. Loera, Andrew B. Civitello , et al. · 2023

Background Postoperative respiratory failure is a major complication that affects up to 10% of patients who undergo cardiac surgery and has a high in-hospital mortality rate. Few studies have investigated whether patients who require trach…

Atrial Fibrillation Burden and Atrial Shunt Therapy in Heart Failure With Preserved Ejection Fraction Open

Ravi B. Patel, Vivek Y. Reddy, Jan Komtebedde, Stephan Wegerich, Jadranka Sekaric , et al. · 2023

PO-05-063 MORTALITY IN LEFT VENTRICULAR ASSIST DEVICE RECIPIENTS WITH VT REQUIRING ABLATION Open

Patrick Lynch, Anish Badjatiya, Abdi Rasekh, Ajith Nair, Mihail G. Chelu · 2023

Left Ventricular Assist Devices and Renal Ramifications Open

Ajith Nair, Harveen K. Lamba · 2023

Neprilysin Inhibitors in Heart Failure Open

Biykem Bozkurt, Ajith Nair, Arunima Misra, Claire Z. Scott, Jamal Mahar , et al. · 2022

COVID-19–Associated Fulminant Myocarditis Open

Ajith Nair, Anita Deswal · 2022

The influence of preoperative dialysis on survival after continuous-flow left ventricular assist device implantation Open

Harveen K. Lamba, Fadi I. Musfee, Subhasis Chatterjee, Ajith Nair, Andrew B. Civitello , et al. · 2021

OBJECTIVES Dialysis is considered a contraindication to continuous-flow left ventricular assist device (CF-LVAD) implantation. We evaluated clinical outcomes and survival in carefully selected, low-risk patients with renal failure who requ…

Patient Characteristics and Outcomes of Type 2 Myocardial Infarction During Heart Failure Hospitalizations in the United States Open

Salik Nazir, Abdul Mannan Khan Minhas, Ishan Kamat, Robert W. Ariss, George V. Moukarbel , et al. · 2021

Sex Specific Utilization and Outcomes in Patients Receiving Continuous-Flow Left Ventricular Devices Open

Harveen K. Lamba, Nandan K. Mondal, Subhasis Chatterjee, Andrew B. Civitello, Ajith Nair , et al. · 2021

Long-Term Outcomes of Adults with Congenital Heart Disease Supported by Durable Continuous-Flow Ventricular Assist Devices Open

William C. Frankel, Chris Broda, Ajith Nair, William J. Dreyer, Hari Tunuguntla , et al. · 2021

Use of Percutaneous Continuous Flow Ventricular Assist Devices in Adults with Congenital Heart Disease Open

Chris Broda, William C. Frankel, Ajith Nair, Hari Tunuguntla, M.C. Anders , et al. · 2021

SARS-CoV-2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis Open

Adam L. Bailey, Oleksandr Dmytrenko, Lina Greenberg, Andrea Bredemeyer, Pan Ma , et al. · 2021

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