V Reddy Chittepu
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View article: 03.06 Cancer-specific oral microbiotherapy for cancer immunotherapy
03.06 Cancer-specific oral microbiotherapy for cancer immunotherapy Open
Background Immunotherapy with immune checkpoint inhibitors (ICI) has revolutionized cancer treatment for many cancers. However, it is associated with low response rates because many cancers have little immune cell infiltration into tumors …
View article: 06.04 Synergistic antitumor activity of pan-PI3K inhibition and immune checkpoint blockade in bladder cancer
06.04 Synergistic antitumor activity of pan-PI3K inhibition and immune checkpoint blockade in bladder cancer Open
Background Immune checkpoint blockade (ICB) induces durable response in approximately 20% of advanced bladder urothelial cancer (aUC) patients. Over 50% of aUCs harbor genomic alterations along the phosphoinositide 3-kinase (PI3K) pathway.…