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View article: Cardiovascular Outcomes with Tirzepatide versus Dulaglutide in Type 2 Diabetes
Cardiovascular Outcomes with Tirzepatide versus Dulaglutide in Type 2 Diabetes Open
Among patients with type 2 diabetes and atherosclerotic cardiovascular disease, tirzepatide was noninferior to dulaglutide with respect to a composite of death from cardiovascular causes, myocardial infarction, or stroke. (Funded by Eli Li…
View article: Initial post-commercialization experience using a thoracic branch endoprosthesis: broad application to real-world patients
Initial post-commercialization experience using a thoracic branch endoprosthesis: broad application to real-world patients Open
OBJECTIVES The first thoracic branched endovascular (TBE) device for arch and proximal descending aortic thoracic endovascular aortic repair (TEVAR) became commercially available in the United States in 2022 (WL Gore, Flagstaff, AZ, USA). …
View article: Textbook outcomes in oesophageal resections from an evolving thoracic surgical unit
Textbook outcomes in oesophageal resections from an evolving thoracic surgical unit Open
Textbook outcome (TO) is a composite metric of surgical quality. This study evaluated TO in oesophageal resections at a low-volume thoracic surgical unit in a Tier-2 city in India, assessing its applicability in a resource-constrained sett…
View article: Association Between Pressure-Adjusted Heart Rate and In-Hospital Mortality in Cardiogenic Shock
Association Between Pressure-Adjusted Heart Rate and In-Hospital Mortality in Cardiogenic Shock Open
PAHR, a simple hemodynamic index calculated from vital signs and central venous pressure, is strongly associated with in-hospital mortality in CS.
View article: In-Hospital Mortality Risk Among Transfers to Cardiac Intensive Care Units
In-Hospital Mortality Risk Among Transfers to Cardiac Intensive Care Units Open
Transfers account for more than 1 of 3 admissions to tertiary CICUs, require more complex care, and have higher mortality compared to nontransfers. These findings have implications for designing regional systems of care, hand-off communica…
View article: Temporary Emergency Guidance to STEMI Systems of Care During the COVID-19 Pandemic: AHA's Mission: Lifeline
Temporary Emergency Guidance to STEMI Systems of Care During the COVID-19 Pandemic: AHA's Mission: Lifeline Open
The American Heart Association (AHA) Get With The Guidelines Coronary Artery Disease Advisory Work Group, and the Acute Care and Interventional Science Subcommittees of the AHA Council on Clinical Cardiology, are responding to the call of …
View article: Real-World Surgical Experience with Thoracic Solitary Fibrous Tumors: Outcomes from a High-Volume Indian Center
Real-World Surgical Experience with Thoracic Solitary Fibrous Tumors: Outcomes from a High-Volume Indian Center Open
This study evaluates the surgical approach, role of trans-arterial angioembolization (TAE) and long-term outcomes of patients presenting with solitary fibrous tumors (SFT) to a tertiary thoracic surgical unit in India. This is a retrospect…
View article: Short-Term Surgical Outcomes of Curative Colorectal Resections from an Evolving Low-Volume Cancer Center in a Tier-2 City in India
Short-Term Surgical Outcomes of Curative Colorectal Resections from an Evolving Low-Volume Cancer Center in a Tier-2 City in India Open
Colorectal cancers (CRC) are the fourth most prevalent cancer in India. Treatment modalities range from surgery, chemotherapy, radiotherapy, targeted treatment, and immunotherapy, with surgery forming the cornerstone of curative treatment …
View article: Analysis of Short-term Outcomes of Pancreatic Resections from a Low Volume Centre in a Tier II City in India
Analysis of Short-term Outcomes of Pancreatic Resections from a Low Volume Centre in a Tier II City in India Open
Pancreatic cancer surgery represents the holy grail of hepatobiliary surgery and is the only option of curative treatment for malignancies involving this particular organ. This study aims to analyse the short-term outcomes of across the sp…
View article: Correlating Left Atrial Enlargement and Left Ventricular Hypertrophy on ECG With Echocardiography and Cardiac Magnetic Resonance Imaging
Correlating Left Atrial Enlargement and Left Ventricular Hypertrophy on ECG With Echocardiography and Cardiac Magnetic Resonance Imaging Open
Background ECGs are a primary assessment of cardiac structure and function. Alignment of their findings with cardiac imaging is not well defined. This study investigates the correlation of left atrial enlargement and left ventricular hyper…
View article: Dual Antiplatelet Therapy (DAPT) in Patients with NSTEMI Undergoing CABG
Dual Antiplatelet Therapy (DAPT) in Patients with NSTEMI Undergoing CABG Open
Background Dual antiplatelet therapy (DAPT), combining acetylsalicylic acid (aspirin) and a P2Y12 inhibitor, is recommended for patients with non-ST segment elevation myocardial infarction (NSTEMI) undergoing coronary artery bypass graftin…
View article: Characteristics and Outcomes of Patients With Cardiogenic Shock and Clinically Significant Valvular Heart Disease: From the Critical Care Cardiology Trials Network
Characteristics and Outcomes of Patients With Cardiogenic Shock and Clinically Significant Valvular Heart Disease: From the Critical Care Cardiology Trials Network Open
VHD is the underlying cause of CS in a minority of CICU admissions but is associated with high in-hospital mortality rates.
View article: Ischemic Dual Papillary Muscle Rupture
Ischemic Dual Papillary Muscle Rupture Open
Mechanical complications following acute myocardial infarction are well characterized and warrant surgical intervention. We present a rare case of a young patient with dual papillary muscle rupture after an episode of diabetic ketoacidosis…
View article: Acute Decompensated Valvular Disease in the Intensive Care Unit
Acute Decompensated Valvular Disease in the Intensive Care Unit Open
Acute decompensated valvular disease encompasses a group of complex and challenging conditions, which are often the primary reason for admission to the cardiac intensive care unit and can also complicate the management of other primary car…
View article: Effects of Tirzepatide on the Clinical Trajectory of Patients With Heart Failure, Preserved Ejection Fraction, and Obesity
Effects of Tirzepatide on the Clinical Trajectory of Patients With Heart Failure, Preserved Ejection Fraction, and Obesity Open
BACKGROUND: Patients with heart failure with preserved ejection fraction and obesity have significant disability and frequent exacerbations of heart failure. We hypothesized that tirzepatide, a long-acting agonist of glucose-dependent insu…
View article: Tirzepatide Reduces LV Mass and Paracardiac Adipose Tissue in Obesity-Related Heart Failure
Tirzepatide Reduces LV Mass and Paracardiac Adipose Tissue in Obesity-Related Heart Failure Open
The CMR substudy of the SUMMIT trial demonstrated that tirzepatide therapy in obesity-related HFpEF led to reduced LV mass and paracardiac adipose tissue as compared with placebo, and the change in LV mass paralleled weight loss. These phy…
View article: Long‐term cardiovascular outcomes of immune checkpoint inhibitor‐related myocarditis: A large single‐centre analysis
Long‐term cardiovascular outcomes of immune checkpoint inhibitor‐related myocarditis: A large single‐centre analysis Open
Aims Immune checkpoint inhibitors (ICI) are the cornerstone of modern oncology; however, side effects such as ICI‐related myocarditis (irM) can be fatal. Recently, Bonaca proposed criteria for irM; however, it is unknown if they correlate …
View article: Occult Pneumomediastinum - An Atypical Presentation of Chest Discomfort in a Patient with Depression
Occult Pneumomediastinum - An Atypical Presentation of Chest Discomfort in a Patient with Depression Open
Pneumomediastinum (mediastinal emphysema) is an uncommon condition characterized by the accumulation of air or gas in the mediastinum. Here is a case of a 16-year-old female known to have depression who presented to the emergency departmen…
View article: Characteristics and Outcomes of Patients With Valvular Cardiogenic Shock
Characteristics and Outcomes of Patients With Valvular Cardiogenic Shock Open
VCS is associated with poor short and long outcomes. Native valvular dysfunction and aortic valve involvement account for the majority of patients with VCS. Definitive surgical therapy and expanding the role of percutaneous therapies may b…