Vishnubhatla Sreenivas
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View article: Pigmentary Changes in Systemic Sclerosis are Associated with More Severe Cutaneous Sclerosis and Severity of Other Systems: A Cross-sectional Study from India
Pigmentary Changes in Systemic Sclerosis are Associated with More Severe Cutaneous Sclerosis and Severity of Other Systems: A Cross-sectional Study from India Open
Background: Pigmentary changes of the skin in systemic sclerosis in the form of diffuse hyperpigmentation and salt-and-pepper pigmentation are well documented in the literature; however, its association with disease severity and extent of …
View article: Original Research Article Genetic Diversity and Association Analysis for Agronomic and Yield Related Traits in Interspecific Progenies of Pigeonpea (Cajanus cajan)
Original Research Article Genetic Diversity and Association Analysis for Agronomic and Yield Related Traits in Interspecific Progenies of Pigeonpea (Cajanus cajan) Open
The limited genetic diversity in existing cultivars emphasizes the need for incorporating potential exotics and wild relatives in breeding programs. This study focussed on assessing genetic variation and correlations among yield traits in …
View article: Comparison of the Clinical Efficacy of Rituximab Infusion and Dexamethasone-Cyclophosphamide Pulse Therapy and Their Effect on Serum Th1, Th2, and Th17 Cytokines in Pemphigus Vulgaris–A Prospective, Nonrandomized, Comparative Pilot Study
Comparison of the Clinical Efficacy of Rituximab Infusion and Dexamethasone-Cyclophosphamide Pulse Therapy and Their Effect on Serum Th1, Th2, and Th17 Cytokines in Pemphigus Vulgaris–A Prospective, Nonrandomized, Comparative Pilot Study Open
Background: Rituximab infusion and dexamethasone-cyclophosphamide pulse (DCP) are the two most popular regimens used in pemphigus vulgaris (PV) in India. Objective: The present study compared the clinical efficacy of rituximab and DCP in I…
View article: Correlation between intestinal stem cell niche changes and small bowel crypt failure in patients with treatment-naïve celiac disease
Correlation between intestinal stem cell niche changes and small bowel crypt failure in patients with treatment-naïve celiac disease Open
Objectives: We hypothesized that crypt failure in the small bowel results in villous flattening in patients with celiac disease (CeD). We investigated whether alterations in the stem cell niche (ISC) are responsible for this phenomenon. Ma…
View article: A Phase III open-label randomized study to compare the efficacy of lenalidomide–rituximab with bendamustine– rituximab in treatment-naïve follicular lymphoma
A Phase III open-label randomized study to compare the efficacy of lenalidomide–rituximab with bendamustine– rituximab in treatment-naïve follicular lymphoma Open
Introduction: Bendamustine–rituximab (BR) is the preferred regimen for the treatment of naïve follicular lymphoma (FL). Recently, lenalidomide–rituximab (LR), a chemotherapy-free protocol, has shown a good response rate in advanced FL. The…
View article: Low serum vitamin D in North Indian multi-drug resistant pulmonary tuberculosis patients: the role of diet and sunlight
Low serum vitamin D in North Indian multi-drug resistant pulmonary tuberculosis patients: the role of diet and sunlight Open
Background: Tuberculosis (TB) and malnutrition are major global health problems, with multidrug-resistant (MDR) TB complicating international efforts. The role of vitamin D in susceptibility to and as an adjunctive treatment for TB …
View article: Issue Information
Issue Information Open
Wiley's Corporate Citizenship initiative seeks to address the environmental, social, economic, and ethical challenges faced in our business and which are important to our diverse stakeholder groups.Since launching the initiative, we have f…
View article: Association of Common Mental Disorders with Diabetes Mellitus – Evidence from Community-based Matched Case–Control Study in North India
Association of Common Mental Disorders with Diabetes Mellitus – Evidence from Community-based Matched Case–Control Study in North India Open
Background: Diabetes mellitus (DM) and depression are major public health problems globally. Evidence of linkage of common mental disorders (CMDs) including depression and anxiety disorders with DM is sparsely reported from community-based…
View article: Can radiofrequency ablation be utilized with equal effect in place of carbon dioxide laser in the treatment of facial angiofibromas in patients of tuberous sclerosis?
Can radiofrequency ablation be utilized with equal effect in place of carbon dioxide laser in the treatment of facial angiofibromas in patients of tuberous sclerosis? Open
Sir, Facial angiofibromas in patients of tuberous sclerosis cause significant cosmetic concern in them. Available medical and surgical modalities for the treatment of angiofibromas are limited.[1,2] Carbon dioxide (CO2) laser has been the …
View article: Normative range of various serum hormonal parameters among Indian women of reproductive age: ICMR-PCOS task force study outcome
Normative range of various serum hormonal parameters among Indian women of reproductive age: ICMR-PCOS task force study outcome Open
The study was financially supported by the grant-in-aid from ICMR vide file No:5/7/13337/2015-RBMH.
View article: Secondary prevention with a structured semi-interactive stroke prevention package in INDIA (SPRINT INDIA): a multicentre, randomised controlled trial
Secondary prevention with a structured semi-interactive stroke prevention package in INDIA (SPRINT INDIA): a multicentre, randomised controlled trial Open
Indian Council of Medical Research.
View article: Assessment of renal allograft rejection with diffusion tensor imaging
Assessment of renal allograft rejection with diffusion tensor imaging Open
Objectives: To investigate the value of DTI in differentiation of renal allograft rejection from well-functioning stable allograft, using fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values. Methods: In this prospect…
View article: Efficacy and Safety of Percutaneous Radiological Gastrostomy (PRG) as a Rescue Measure for Enteral Feeding in Patients with Advanced Head, Neck, and Upper Digestive Malignancies
Efficacy and Safety of Percutaneous Radiological Gastrostomy (PRG) as a Rescue Measure for Enteral Feeding in Patients with Advanced Head, Neck, and Upper Digestive Malignancies Open
Background Percutaneous radiologic gastrostomy is an established mode of enteral feeding for nutritional support for patients with dysphagia from upper digestive tract malignancy. Its role as a rescue measure in patients with advanced mali…
View article: Central Venous Catheter Related Bloodstream Infections in Medical Intensive Care Unit Patients in a Tertiary Referral Centre
Central Venous Catheter Related Bloodstream Infections in Medical Intensive Care Unit Patients in a Tertiary Referral Centre Open
line (CL) days in adult and paediatric ICUs and from 2.6 to 60.0 cases per 1000 CL days in NICUs 6 (Table 1).Various authors have reported variable data on CLABSIs from India. 7-9Notably, Mehta et al 7 reported an overall hospital associat…
View article: Azithromycin resistance and its molecular characteristics in Neisseria gonorrhoeae isolates from a tertiary care centre in North India
Azithromycin resistance and its molecular characteristics in Neisseria gonorrhoeae isolates from a tertiary care centre in North India Open
Treatment guidelines for management of uncomplicated gonorrhoeae have been recently modified owing to alarming upsurge in azithromycin resistance. This study investigated the prevalence and genetic determinants of gonococcal azithromycin r…
View article: Abstracts\' Service
Abstracts\' Service Open
Background.Obstructive sleep apnea is associated with an increased prevalence of the metabolic syndrome and its components.It is unclear whether treatment of obstructive sleep apnea syndrome with continuous positive airway pressure (CPAP) …
View article: Histologic Changes in Core-Needle Liver Biopsies From Patients With Acute-on-Chronic Liver Failure and Independent Histologic Predictors of 28-Day Mortality
Histologic Changes in Core-Needle Liver Biopsies From Patients With Acute-on-Chronic Liver Failure and Independent Histologic Predictors of 28-Day Mortality Open
Context.— The histologic features in patients with acute-on-chronic liver failure (ACLF) are evolving, and histologic indicators of patients' poor prognosis are not yet fully established. Objective.— To evaluate the independent histologic …
View article: Prevalence, pattern & correlates of hypertension among tribal population of Kashmir, India
Prevalence, pattern & correlates of hypertension among tribal population of Kashmir, India Open
Background & objectives: The prevalence of hypertension is increasing among all ethnic groups across the globe with only a handful of studies from India addressing the prevalence of hypertension among tribal population. In view of paucity …
View article: Efficacy of NB-UVB in Progressive Versus Non-Progressive Non-Segmental Vitiligo
Efficacy of NB-UVB in Progressive Versus Non-Progressive Non-Segmental Vitiligo Open
Introduction: Narrow-band (NB) ultraviolet B (UVB) phototherapy has been shown to halt disease progression in vitiligo, but whether there is any difference in the response to NB-UVB seen in patients with progressive vitiligo versus non-pro…
View article: Alfacalcidol<i>vs</i>Calcitriol in the Management of Patient With Hypoparathyroidism: A Randomized Controlled Trial
Alfacalcidol<i>vs</i>Calcitriol in the Management of Patient With Hypoparathyroidism: A Randomized Controlled Trial Open
Context Alfacalcidol and calcitriol are commonly used for managing hypoparathyroidism. Their relative merits have not been systematically assessed. Objective We compared the effect of alfacalcidol and calcitriol on phosphatemic control, hy…
View article: Prognostic and Therapeutic Potentials of OncomiRs Modulating mTOR Pathways in Virus-Associated Hepatocellular Carcinoma
Prognostic and Therapeutic Potentials of OncomiRs Modulating mTOR Pathways in Virus-Associated Hepatocellular Carcinoma Open
Background Dysregulated oncomiRs are attributed to hepatocellular carcinoma (HCC) through targeting mTOR signaling pathway responsible for cell growth and proliferation. The potential of these oncomiRs as biomarker for tumor response or as…
View article: Evaluation of the Prevalence, Regional Phenotypic Variation, Comorbidities, Risk Factors, and Variations in Response to Different Therapeutic Modalities Among Indian Women: Proposal for the Indian Council of Medical Research–Polycystic Ovary Syndrome (ICMR–PCOS) Study
Evaluation of the Prevalence, Regional Phenotypic Variation, Comorbidities, Risk Factors, and Variations in Response to Different Therapeutic Modalities Among Indian Women: Proposal for the Indian Council of Medical Research–Polycystic Ovary Syndrome (ICMR–PCOS) Study Open
Background There is scanty data in India on polycystic ovary syndrome (PCOS) from several small, undersized, convenience-based studies employing differing diagnostic criteria and reporting varied regional prevalence. It is difficult to dra…
View article: Clinical Features, Gender Differences, Disease Course, and Outcome in Neuromyelitis Optica Spectrum Disorder
Clinical Features, Gender Differences, Disease Course, and Outcome in Neuromyelitis Optica Spectrum Disorder Open
Introduction: Neuromyelitis optica spectrum disorder (NMOSD) is an astrocytopathy with a predilection for the optic nerve, spinal cord, and brainstem. In this ambispective study, we evaluate clinical characteristics, responses to therapy, …
View article: The utility of dithiothreitol treatment of periprosthetic tissues and explanted implants in the diagnosis of prosthetic joint infection
The utility of dithiothreitol treatment of periprosthetic tissues and explanted implants in the diagnosis of prosthetic joint infection Open
We could verify that DTT can be used to improve culture outcome in laboratories where biofilm detaching sonication techniques are not available for infected implants. In addition, we showed that it is possible to use DTT for treating tissu…
View article: Etiology of genital ulcer disease in patients attending the sexually transmitted disease clinic of a tertiary care hospital: Evaluation of multiplex PCR assay for diagnosis
Etiology of genital ulcer disease in patients attending the sexually transmitted disease clinic of a tertiary care hospital: Evaluation of multiplex PCR assay for diagnosis Open
View article: Modified ultrafiltration & postoperative course in patients undergoing repair of Tetralogy of Fallot
Modified ultrafiltration & postoperative course in patients undergoing repair of Tetralogy of Fallot Open
Background: Expected benefits of modified ultrafiltration(MUF) include increased hematocrit, reduction of total body water & inflammatory mediators, improved left ventricular systolic function, & improved systolic blood pressure and cardiac i…
View article: Olanzapine for Prevention of Vomiting in Children and Adolescents Receiving Highly Emetogenic Chemotherapy: Investigator-Initiated, Randomized, Open-Label Trial
Olanzapine for Prevention of Vomiting in Children and Adolescents Receiving Highly Emetogenic Chemotherapy: Investigator-Initiated, Randomized, Open-Label Trial Open
PURPOSE Chemotherapy-induced nausea and vomiting (CINV) is a significant toxicity of chemotherapy. Olanzapine is recommended in adult patients for the prevention of CINV but has not been prospectively investigated in children. METHODS This…
View article: Evaluation of the Prevalence, Regional Phenotypic Variation, Comorbidities, Risk Factors, and Variations in Response to Different Therapeutic Modalities Among Indian Women: Proposal for the Indian Council of Medical Research–Polycystic Ovary Syndrome (ICMR–PCOS) Study (Preprint)
Evaluation of the Prevalence, Regional Phenotypic Variation, Comorbidities, Risk Factors, and Variations in Response to Different Therapeutic Modalities Among Indian Women: Proposal for the Indian Council of Medical Research–Polycystic Ovary Syndrome (ICMR–PCOS) Study (Preprint) Open
BACKGROUND There is scanty data in India on polycystic ovary syndrome (PCOS) from several small, undersized, convenience-based studies employing differing diagnostic criteria and reporting varied regional prevalence. It is difficult to dr…
View article: Evaluation of a Chip-Based, Point-of-Care, Portable, Real-Time Micro PCR Analyzer for the Detection of High-Risk Human Papillomavirus in Uterine Cervix in India
Evaluation of a Chip-Based, Point-of-Care, Portable, Real-Time Micro PCR Analyzer for the Detection of High-Risk Human Papillomavirus in Uterine Cervix in India Open
PURPOSE Currently available human papillomavirus (HPV) detection devices are expensive, requiring a continuous power supply, high-priced reagents, skilled laboratory personnel, and infrastructure. These make it difficult to implement prima…
View article: Burden of influenza-associated respiratory and circulatory mortality in India, 2010-2013
Burden of influenza-associated respiratory and circulatory mortality in India, 2010-2013 Open
Estimated influenza-associated mortality in India was high among children <5 years and adults ≥65 years. These estimates may inform strategies for influenza prevention and control in India, such as possible vaccine introduction.