Ashish V. Joshi
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View article: Prevalence and economic evaluation of acute uncomplicated cystitis in women from Japan: a retrospective cohort study
Prevalence and economic evaluation of acute uncomplicated cystitis in women from Japan: a retrospective cohort study Open
Background Although Japanese guidelines recommend fluoroquinolones (FQs) and cephalosporins for AUC (acute uncomplicated cystitis) treatment, the emergence of FQ-resistant uropathogens and inappropriate use of antibiotics may lead to treat…
View article: P60 Antimicrobial resistance among female patients with uncomplicated urinary tract infections in England: a physician panel chart review
P60 Antimicrobial resistance among female patients with uncomplicated urinary tract infections in England: a physician panel chart review Open
Background Antimicrobial resistance (AMR) is a significant and growing public health concern. Data on the prevalence of AMR can optimize antimicrobial prescribing choices and highlight unmet need in the treatment landscape. Surveillance da…
View article: Poetry and Mental Health: A Therapeutic Connection
Poetry and Mental Health: A Therapeutic Connection Open
View article: P-1550. Systematic Literature Review of Acute Cystitis or Afebrile Urinary Tract Infection in Men
P-1550. Systematic Literature Review of Acute Cystitis or Afebrile Urinary Tract Infection in Men Open
Background Acute cystitis in men is classified as complicated urinary tract infection (UTI), despite the absence of functional and/or structural anatomical abnormalities of the urinary tract, associated with a higher risk of treatment fail…
View article: P-1566. Healthcare Resource Use and Costs of Acute Uncomplicated Cystitis in Japan
P-1566. Healthcare Resource Use and Costs of Acute Uncomplicated Cystitis in Japan Open
Background Acute uncomplicated cystitis (AUC) is an area of interest for outpatient antimicrobial stewardship in Japan due to the high prevalence of community antibiotic use. Literature on the cost burden of AUC in Japan is limited. We aim…
View article: Reinforcement Learning-Enhanced Procedural Generation for Dynamic Narrative-Driven AR Experiences
Reinforcement Learning-Enhanced Procedural Generation for Dynamic Narrative-Driven AR Experiences Open
Procedural Content Generation (PCG) is widely used to create scalable and diverse environments in games. However, existing methods, such as the Wave Function Collapse (WFC) algorithm, are often limited to static scenarios and lack the adap…
View article: Activity impairment, work productivity, health-related quality-of-life, and costs associated with uncomplicated urinary tract infection among females in Germany
Activity impairment, work productivity, health-related quality-of-life, and costs associated with uncomplicated urinary tract infection among females in Germany Open
Uncomplicated urinary tract infections (uUTIs) represent a sizable healthcare burden with a substantial negative impact on patients’ health-related quality-of-life (HRQoL). However, the HRQoL impact of uUTI from the patient perspective is …
View article: Early Breastfeeding Concerns Among a Diverse Population of Mothers
Early Breastfeeding Concerns Among a Diverse Population of Mothers Open
View article: Treatment patterns and burden of uncomplicated urinary tract infection in England: a retrospective cohort study
Treatment patterns and burden of uncomplicated urinary tract infection in England: a retrospective cohort study Open
Background Uncomplicated urinary tract infections (uUTIs) are common bacterial infections. Aim To evaluate the burden of uUTI in England for 1) potential determinants of disease progression; 2) extent and impact of antimicrobial prescribin…
View article: Allergies to antibiotics among US women with uncomplicated urinary tract infection
Allergies to antibiotics among US women with uncomplicated urinary tract infection Open
Uncomplicated urinary tract infections (uUTI) are generally treated empirically with antibiotics. However, antibiotic allergies limit the available oral treatment options for some patients. We assessed the proportion of self-reported antib…
View article: Treatment Patterns and Adherence to Guidelines for Uncomplicated Urinary Tract Infection in Germany: A Retrospective Cohort Study
Treatment Patterns and Adherence to Guidelines for Uncomplicated Urinary Tract Infection in Germany: A Retrospective Cohort Study Open
A high proportion of prescribed treatments for the initial uUTI episode were not recommended by German uUTI guidelines as first-choice antibiotics. Prescribing adherence varied by physician specialty; specialists showed greater adherence t…
View article: Co-resistance Among Escherichia coli and Klebsiella pneumoniae Urine Isolates from Female Outpatients with Presumed UTI: A Retrospective US Cohort Study
Co-resistance Among Escherichia coli and Klebsiella pneumoniae Urine Isolates from Female Outpatients with Presumed UTI: A Retrospective US Cohort Study Open
Both species exhibited high rates of co-resistance, emphasizing the need to raise awareness of co-resistance and of the unmet need for effective treatment options for uUTI.
View article: Development of Predictive Models to Inform a Novel Risk Categorization Framework for Antibiotic Resistance in <i>Escherichia coli–</i>Caused Uncomplicated Urinary Tract Infection
Development of Predictive Models to Inform a Novel Risk Categorization Framework for Antibiotic Resistance in <i>Escherichia coli–</i>Caused Uncomplicated Urinary Tract Infection Open
Background In clinical practice, challenges in identifying patients with uncomplicated urinary tract infections (uUTIs) at risk of antibiotic nonsusceptibility may lead to inappropriate prescribing and contribute to antibiotic resistance. …
View article: Prevalence, regional distribution, and trends of antimicrobial resistance among female outpatients with urine Klebsiella spp. isolates: a multicenter evaluation in the United States between 2011 and 2019
Prevalence, regional distribution, and trends of antimicrobial resistance among female outpatients with urine Klebsiella spp. isolates: a multicenter evaluation in the United States between 2011 and 2019 Open
Background Antimicrobial resistance research in uncomplicated urinary tract infection typically focuses on the main causative pathogen, Escherichia coli ; however, little is known about the antimicrobial resistance burden of Klebsiella spe…
View article: 2838. Clinical Application and Validation of a Predictive Antimicrobial Resistance Risk Categorization Framework for Patients with Uncomplicated Urinary Tract Infection
2838. Clinical Application and Validation of a Predictive Antimicrobial Resistance Risk Categorization Framework for Patients with Uncomplicated Urinary Tract Infection Open
Background Empiric antibiotic (ABX) treatment for uncomplicated urinary tract infections (uUTIs) can be ineffective due to antimicrobial resistance (AMR). Understanding the risk of AMR using data-driven approaches can inform appropriate AB…
View article: 2839. Cost Burden of Patients with Oral Antibiotic Treatment Failure for Uncomplicated Urinary Tract Infection in the United States
2839. Cost Burden of Patients with Oral Antibiotic Treatment Failure for Uncomplicated Urinary Tract Infection in the United States Open
Background Urinary tract infections (UTIs) are the most common bacterial infections in women. Antibiotics (ABX) are available to treat uncomplicated UTI (uUTI), but 10–30% of patients experience treatment failure (TF). We assessed uUTI-rel…
View article: 2840. Prevalence of Acute Uncomplicated Cystitis in Japan
2840. Prevalence of Acute Uncomplicated Cystitis in Japan Open
Background Urinary tract infections (UTIs) are among the most common bacterial infections worldwide. Uncomplicated UTI, or acute uncomplicated cystitis (AUC), is an area of interest for antimicrobial stewardship in Japan due to high preval…
View article: P17 Baseline characteristics, disease progression rates and risk factors among female patients with uncomplicated urinary tract infection in England
P17 Baseline characteristics, disease progression rates and risk factors among female patients with uncomplicated urinary tract infection in England Open
Background and Objectives Uncomplicated urinary tract infection (uUTI) is a common, usually community-acquired bacterial infection. Little is known about risk factors for disease progression (defined here as hospitalization for Escherichia…
View article: P19 Burden of illness and costs among female patients with uncomplicated urinary tract infection in England
P19 Burden of illness and costs among female patients with uncomplicated urinary tract infection in England Open
Background and Objectives Uncomplicated urinary tract infection (uUTI) is usually community-acquired. Data regarding the wider burden of illness from uUTI are scarce. We evaluated the burden of uUTI in female patients in England. Methods T…
View article: P18 Treatment patterns and extent of inappropriate antimicrobial treatment among female patients with uncomplicated urinary tract infection in England
P18 Treatment patterns and extent of inappropriate antimicrobial treatment among female patients with uncomplicated urinary tract infection in England Open
Background and Objectives Inappropriate antimicrobial treatment of uncomplicated urinary tract infection (uUTI) has potential impacts on healthcare resource use and costs. We characterized treatment patterns for uUTI in England, including …
View article: Escherichia coli resistance, treatment patterns and clinical outcomes among females with uUTI in Germany: a retrospective physician-based chart review study
Escherichia coli resistance, treatment patterns and clinical outcomes among females with uUTI in Germany: a retrospective physician-based chart review study Open
View article: Older patient age and prior antimicrobial use strongly predict antimicrobial resistance in Escherichia coli isolates recovered from urinary tract infections among female outpatients
Older patient age and prior antimicrobial use strongly predict antimicrobial resistance in Escherichia coli isolates recovered from urinary tract infections among female outpatients Open
Background Increasing prevalence of antimicrobial resistance (AMR), including multidrug resistance (MDR), among Escherichia coli ( E . coli ) makes treatment of uncomplicated urinary tract infection (uUTI) difficult. We assessed risk facto…
View article: Unmet needs in uncomplicated urinary tract infection in the United States and Germany: a physician survey
Unmet needs in uncomplicated urinary tract infection in the United States and Germany: a physician survey Open
View article: Activity impairment, health-related quality of life, productivity, and self-reported resource use and associated costs of uncomplicated urinary tract infection among women in the United States
Activity impairment, health-related quality of life, productivity, and self-reported resource use and associated costs of uncomplicated urinary tract infection among women in the United States Open
Background Uncomplicated urinary tract infections (uUTIs) are among the most common infections in the US. Only a few studies, however, describe the impact of uUTIs from the patient perspective. Methods A cross-sectional online survey of US…
View article: Treatment patterns, healthcare resource use, and costs associated with uncomplicated urinary tract infection among female patients in the United States
Treatment patterns, healthcare resource use, and costs associated with uncomplicated urinary tract infection among female patients in the United States Open
Background We evaluated associations between antibiotic prescription and healthcare resource use and costs (Part A), and between antibiotic switching and healthcare resource use, costs, and uncomplicated urinary tract infection recurrence …
View article: Risk Factors Associated With Antimicrobial Resistance and Adverse Short-Term Health Outcomes Among Adult and Adolescent Female Outpatients With Uncomplicated Urinary Tract Infection
Risk Factors Associated With Antimicrobial Resistance and Adverse Short-Term Health Outcomes Among Adult and Adolescent Female Outpatients With Uncomplicated Urinary Tract Infection Open
Background Increasing antimicrobial resistance makes treating uncomplicated urinary tract infections (uUTIs) difficult. We compared whether adverse short-term outcomes among US female patients were more common when initial antimicrobial th…
View article: Impact of suboptimal or inappropriate treatment on healthcare resource use and cost among patients with uncomplicated urinary tract infection: an analysis of integrated delivery network electronic health records
Impact of suboptimal or inappropriate treatment on healthcare resource use and cost among patients with uncomplicated urinary tract infection: an analysis of integrated delivery network electronic health records Open
Background Although uncomplicated urinary tract infections (uUTIs; occurring in female patients without urological abnormalities or history of urological procedures or complicating comorbidities) are one of the most common community infect…
View article: Economic burden of antibiotic-not-susceptible isolates in uncomplicated urinary tract infection: Analysis of a US integrated delivery network database
Economic burden of antibiotic-not-susceptible isolates in uncomplicated urinary tract infection: Analysis of a US integrated delivery network database Open
Background Uncomplicated urinary tract infections (uUTIs) are one of the most common bacterial infections in the United States (US). Contemporary data are important for understanding the health economic impact of antimicrobial-resistant uU…
View article: 1415. Allergies to Antimicrobial Agents Among US Females with Uncomplicated Urinary Tract Infection
1415. Allergies to Antimicrobial Agents Among US Females with Uncomplicated Urinary Tract Infection Open
Background Uncomplicated urinary tract infections (uUTI) are generally treated empirically with antibiotics. However, antibiotic (AB) allergies limit the available oral treatment options for some patients. We assessed the proportion of sel…
View article: 197. Healthcare Resource Utilization and Costs Associated with Inappropriate and Suboptimal Prescribing of Antibiotics for Uncomplicated Urinary Tract Infection in the United States
197. Healthcare Resource Utilization and Costs Associated with Inappropriate and Suboptimal Prescribing of Antibiotics for Uncomplicated Urinary Tract Infection in the United States Open
Background Despite well-established guidelines for urinary tract infection (UTI) treatment, prescribing practices vary. We examined the association between inappropriate (IA) or suboptimal (SO) antibiotic (AB) prescribing (RX) and hospital…