Anna Valenzano
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View article: Impact of Exercise Therapy in ERAS Prehabilitation for Major Surgery: A Systematic Review
Impact of Exercise Therapy in ERAS Prehabilitation for Major Surgery: A Systematic Review Open
(1) This systematic review evaluates the role of structured exercise within the Enhanced Recovery After Surgery (ERAS) protocol, a multidisciplinary approach designed to reduce surgical stress and enhance recovery. Prehabilitation, primari…
View article: Repetitive transcranial magnetic stimulation in children and adolescents with autism spectrum disorder: study protocol for a double-blind, sham-controlled, randomized clinical trial
Repetitive transcranial magnetic stimulation in children and adolescents with autism spectrum disorder: study protocol for a double-blind, sham-controlled, randomized clinical trial Open
The study protocol is registered at "ClinicalTrials.gov" with the following ID: NCT06069323.
View article: Influence of Intermittent Fasting on Body Composition, Physical Performance, and the Orexinergic System in Postmenopausal Women: A Pilot Study
Influence of Intermittent Fasting on Body Composition, Physical Performance, and the Orexinergic System in Postmenopausal Women: A Pilot Study Open
Objective: This study aims to evaluate the effects of different nutritional strategies, specifically intermittent fasting (IF) combined with high-intensity interval training (HIIT) versus a low-calorie diet (LCD), on body composition, phys…
View article: Potential Protective Effects of Spirulina (Spirulina platensis) against In Vitro Toxicity Induced by Heavy Metals (Cadmium, Mercury, and Lead) on SH-SY5Y Neuroblastoma Cells
Potential Protective Effects of Spirulina (Spirulina platensis) against In Vitro Toxicity Induced by Heavy Metals (Cadmium, Mercury, and Lead) on SH-SY5Y Neuroblastoma Cells Open
Spirulina, a filamentous microalga, is used all over the world as a nutraceutical dietary supplement. Recent studies have focused on examining its chelating activity and antioxidant properties, especially as a candidate for protection agai…
View article: Relationship between Cortical Excitability and Complex Reaction Time
Relationship between Cortical Excitability and Complex Reaction Time Open
Introduction: The purpose of this investigation was to investigate the relationships between cortical excitability and complex reaction times (RT).To carry out this study, we performed transcranial magnetic stimulation (TMS) to test cortic…
View article: The Effect of Calcium Ions on hIAPP Channel Activity: Possible Implications in T2DM
The Effect of Calcium Ions on hIAPP Channel Activity: Possible Implications in T2DM Open
The calcium ion (Ca2+) has been linked to type 2 diabetes mellitus (T2DM), although the role of Ca2+ in this disorder is the subject of intense investigation. Serum Ca2+ dyshomeostasis is associated with the development of insulin resistan…
View article: The Role of BIA Analysis in Osteoporosis Risk Development: Hierarchical Clustering Approach
The Role of BIA Analysis in Osteoporosis Risk Development: Hierarchical Clustering Approach Open
Osteoporosis is a common musculoskeletal disorder among the elderly and a chronic condition which, like many other chronic conditions, requires long-term clinical management. It is caused by many factors, including lifestyle and obesity. B…
View article: The Differences in Physical Activity Levels of Male and Female University Students
The Differences in Physical Activity Levels of Male and Female University Students Open
Study purpose. The aim of this study was to examine the levels of physical activity among undergraduates living in ADISU (Agency for the Right to University Study) residences in order to better understand their situations and highlight the…
View article: Agomelatine: A Potential Multitarget Compound for Neurodevelopmental Disorders
Agomelatine: A Potential Multitarget Compound for Neurodevelopmental Disorders Open
Agomelatine (AGM) is one of the latest atypical antidepressants, prescribed exclusively for the treatment of depression in adults. AGM belongs to the pharmaceutical class of melatonin agonist and selective serotonin antagonist (“MASS”), as…
View article: α-Tocopherol Protects Lipopolysaccharide-Activated BV2 Microglia
α-Tocopherol Protects Lipopolysaccharide-Activated BV2 Microglia Open
Microglia, the resident macrophage-like population in the central nervous system, play a crucial role in the pathogenesis of many neurodegenerative disorders by triggering an inflammatory response that leads to neuronal death. Neuroprotect…
View article: Transcranial magnetic stimulation as a new therapeutical approach in autism spectrum disorders and attention deficit hyperactivity disorder – a review
Transcranial magnetic stimulation as a new therapeutical approach in autism spectrum disorders and attention deficit hyperactivity disorder – a review Open
Introduction and aim. Autism spectrum disorders (ASD) and attention deficit hyperactivity disorder (ADHD) neurobiology reveals a complex picture of altered excitation-inhibition balance, aberrant neuronal and neurotransmitter activity, and…
View article: The Ketogenic Diet and Neuroinflammation: The Action of Beta-Hydroxybutyrate in a Microglial Cell Line
The Ketogenic Diet and Neuroinflammation: The Action of Beta-Hydroxybutyrate in a Microglial Cell Line Open
The ketogenic diet (KD), a diet high in fat and protein but low in carbohydrates, is gaining much interest due to its positive effects, especially in neurodegenerative diseases. Beta-hydroxybutyrate (BHB), the major ketone body produced du…
View article: Aerobic and Anaerobic Effect of CrossFit Training: A Narrative Review
Aerobic and Anaerobic Effect of CrossFit Training: A Narrative Review Open
CrossFit is recognized as one of the fastest growing modes of high-intensity functional training. This strength and conditioning program is used to optimize physical competence in ten fitness domains: (1) cardiovascular/ respiratory endura…
View article: Correction: La Torre et al. Role of Vitamin E and the Orexin System in Neuroprotection. Brain Sci. 2021, 11, 1098
Correction: La Torre et al. Role of Vitamin E and the Orexin System in Neuroprotection. Brain Sci. 2021, 11, 1098 Open
In the original article [...]
View article: Twelve Weeks of Aerobic Training to Increase VO₂max in Sedentary Young Males
Twelve Weeks of Aerobic Training to Increase VO₂max in Sedentary Young Males Open
Study purpose. The aim of this study was to verify the effect of three sessions of aerobic training, for a period of 12 weeks, on VO2max and on the distance covered during the test. Materials and Methods. Fifteen sedentary males were recru…
View article: Lifestyle in Obese Individuals during the COVID-19 Pandemic
Lifestyle in Obese Individuals during the COVID-19 Pandemic Open
Background: Stay-at-home orders in response to the Coronavirus 2 (SARS-CoV-2) pandemic have forced abrupt changes to daily routines. The aim of this study is to describe the behavior of lifestyles of individuals with obesity on the waiting…
View article: Factorial Model of Obese Adolescents: The Role of Body Image Concerns and Selective Depersonalization—A Pilot Study
Factorial Model of Obese Adolescents: The Role of Body Image Concerns and Selective Depersonalization—A Pilot Study Open
Background: The relationship binding body weight to psychological well-being is unclear. The present study aims at identifying the contribution, and specificity, of some dimensions (i.e., eating-related symptoms, body image disorders, eati…
View article: The Influence of Physical Exercise, Stress and Body Composition on Autonomic Nervous System: A Narrative Review
The Influence of Physical Exercise, Stress and Body Composition on Autonomic Nervous System: A Narrative Review Open
The heart rate variability (HRV) changes under different situations such as physical exercise, stress and in obese/ overweight subjects. It is considered a noninvasive marker of autonomic nervous system function. The aim of this narrative …
View article: The Beneficial Effects of Physical Activity in Lung Cancer Prevention and/or Treatment
The Beneficial Effects of Physical Activity in Lung Cancer Prevention and/or Treatment Open
Lung cancer is the most lethal cancer: it has a significant incidence and low survival rates. Lifestyle has an important influence on cancer onset and its progression, indeed environmental factors and smoke are involved in cancer establish…
View article: Heart Rate Variability and Sympathetic Activity Is Modulated by Very Low-Calorie Ketogenic Diet
Heart Rate Variability and Sympathetic Activity Is Modulated by Very Low-Calorie Ketogenic Diet Open
Obesity is characterized by an energy imbalance and by the accumulation of visceral adipose tissue. The energy balance is controlled by a complex set of balanced physiological systems that provide hunger and satiety signals to the brain an…
View article: Effects of Mixed of a Ketogenic Diet in Overweight and Obese Women with Polycystic Ovary Syndrome
Effects of Mixed of a Ketogenic Diet in Overweight and Obese Women with Polycystic Ovary Syndrome Open
Polycystic ovary syndrome (PCOS) is a commonly occurring endocrine disorder characterized by hirsutism, anovulation, and polycystic ovaries. Often comorbid with insulin resistance, dyslipidemia, and obesity, it also carries significant ris…
View article: The Role of Very Low Calorie Ketogenic Diet in Sympathetic Activation through Cortisol Secretion in Male Obese Population
The Role of Very Low Calorie Ketogenic Diet in Sympathetic Activation through Cortisol Secretion in Male Obese Population Open
Adipose tissue is considered an endocrine organ, and its excess compromises the immune response and metabolism of hormones and nutrients. Furthermore, the accumulation of visceral fat helps to increase the synthesis of cortisol. The hypoth…
View article: Role of Vitamin E and the Orexin System in Neuroprotection
Role of Vitamin E and the Orexin System in Neuroprotection Open
Microglia are the first line of defense at the level of the central nervous system (CNS). Phenotypic change in microglia can be regulated by various factors, including the orexin system. Neuroinflammation is an inflammatory process mediate…
View article: Very Low-Calorie Ketogenic Diet Modulates the Autonomic Nervous System Activity through Salivary Amylase in Obese Population Subjects
Very Low-Calorie Ketogenic Diet Modulates the Autonomic Nervous System Activity through Salivary Amylase in Obese Population Subjects Open
In obesity, to reduce visceral adipose tissue (VAT), caloric restriction is a valid strategy. Salivary amylase is an enzyme that cleaves large starch carbohydrates molecules and its production is modulated by the central nervous system. In…
View article: Transcranial Magnetic Stimulation as a Tool to Investigate Motor Cortex Excitability in Sport
Transcranial Magnetic Stimulation as a Tool to Investigate Motor Cortex Excitability in Sport Open
Transcranial magnetic stimulation, since its introduction in 1985, has brought important innovations to the study of cortical excitability as it is a non-invasive method and, therefore, can be used both in healthy and sick subjects. Since …
View article: COVID-19: Role of Nutrition and Supplementation
COVID-19: Role of Nutrition and Supplementation Open
At the end of 2019, a new coronavirus (COVID-19) appeared on the world scene, which mainly affects the respiratory system, causing pneumonia and multi-organ failure, and, although it starts with common symptoms such as shortness of breath …
View article: Effects of a Plastic-Free Lifestyle on Urinary Bisphenol A Levels in School-Aged Children of Southern Italy: A Pilot Study
Effects of a Plastic-Free Lifestyle on Urinary Bisphenol A Levels in School-Aged Children of Southern Italy: A Pilot Study Open
Bisphenol A (BPA) is an endocrine disruptor (ED) frequently used in food packaging. BPA is used as a monomer in the manufacture of some food packaging. This study aimed to evaluate the urinary BPA concentration in an Italian pediatric coho…
View article: The Social Brain and Emotional Contagion: COVID-19 Effects
The Social Brain and Emotional Contagion: COVID-19 Effects Open
Background and objectives: Coronavirus disease 2019 (COVID-19) is a highly contagious infectious disease, responsible for a global pandemic that began in January 2020. Human/COVID-19 interactions cause different outcomes ranging from minor…
View article: The Metabolic Rearrangements of Bariatric Surgery: Focus on Orexin-A and the Adiponectin System
The Metabolic Rearrangements of Bariatric Surgery: Focus on Orexin-A and the Adiponectin System Open
The accumulation of adipose tissue represents one of the characteristics of obesity, increasing the risk of developing correlated obesity diseases such as cardiovascular disease, type 2 diabetes, cancer, and immune diseases. Visceral adipo…