Vadanya Shrivastava
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View article: Faricimab for Refractory Neovascular Age-Related Macular Degeneration: Retrospective Real-World Evidence from India
Faricimab for Refractory Neovascular Age-Related Macular Degeneration: Retrospective Real-World Evidence from India Open
In this real-world Indian cohort of refractory nAMD, faricimab delivered robust visual gains, significant CFT reduction, and high rates of fluid resolution, with over half of eyes requiring ≤2 injections over six months, supporting its rol…
View article: Using human fetal neural stem cells to elucidate the role of the JAK-STAT cell signaling pathway in oligodendrocyte differentiation in vitro
Using human fetal neural stem cells to elucidate the role of the JAK-STAT cell signaling pathway in oligodendrocyte differentiation in vitro Open
Oligodendrocytes (OL) are the myelinating cells of the central nervous system that mediate nerve conduction. Loss of oligodendrocytes results in demyelination, triggering neurological deficits. Developing a better understanding of the cell…
View article: Hypoxia induces early neurogenesis in human fetal neural stem cells by activating the WNT pathway
Hypoxia induces early neurogenesis in human fetal neural stem cells by activating the WNT pathway Open
Fetal neural stem cells (FNSCs) present in the human fetal brain, differentiate into cells of neuronal and glial lineages. The developing fetus is exposed to lower oxygen concentrations compared to adults and this physiological hypoxia may…
View article: Glutamate Uptake Is Not Impaired by Hypoxia in a Culture Model of Human Fetal Neural Stem Cell-Derived Astrocytes
Glutamate Uptake Is Not Impaired by Hypoxia in a Culture Model of Human Fetal Neural Stem Cell-Derived Astrocytes Open
Hypoxic ischemic injury to the fetal and neonatal brain is a leading cause of death and disability worldwide. Although animal and culture studies suggest that glutamate excitotoxicity is a primary contributor to neuronal death following hy…
View article: Hypoxia induces early neurogenesis in human fetal neural stem cells by activating the WNT pathway
Hypoxia induces early neurogenesis in human fetal neural stem cells by activating the WNT pathway Open
Fetal neural stem cells (FNSCs) are present in the brain of human fetuses that differentiate into cells of neuronal and glial lineages. Difference in oxygen concentration between maternal and fetal circulation indicates that the developing…
View article: Human fetal neural stem cell-derived astrocytes maintain glutamate transport after hypoxic injury <i>in vitro</i>
Human fetal neural stem cell-derived astrocytes maintain glutamate transport after hypoxic injury <i>in vitro</i> Open
Astrocytes are the most abundant glial cells that play many critical roles in the central nervous system physiology including the uptake of excess glutamate from the synapse by Excitatory Amino Acid Transporters (EAATs). Among the EAATs, E…
View article: Study of Ocular Manifestations in Patients Hospitalized with Dengue Fever
Study of Ocular Manifestations in Patients Hospitalized with Dengue Fever Open
Objective: To study the clinical spectrum of ocular manifestations in patients hospitalized with dengue fever during a dengue outbreak.Design: It is a cross-sectional observational study, designed to determine the prevalence of ocular sign…