Vaibhav Pandey
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View article: In-Silico Study of Thiazolidinone-linked Glu-Ureido based PSMA Ligands for PET Applications
In-Silico Study of Thiazolidinone-linked Glu-Ureido based PSMA Ligands for PET Applications Open
Introduction: The Prostate Specific Membrane Antigen (PSMA) is a type II transmembrane glycoprotein known as Glutamate Carboxypeptidase II, overexpressed in prostate carcinoma. The Glu-Ureido moiety is a target-specific inhibitor for PSMA,…
View article: Slope Stability Analysis of Highway Embankments Using Strength Reduction Method in PLAXIS 3D
Slope Stability Analysis of Highway Embankments Using Strength Reduction Method in PLAXIS 3D Open
Slope stability analysis is vital in geotechnical and highway engineering due to its direct implications on infrastructure safety and serviceability. This study employs the Strength Reduction Method (SRM) in PLAXIS 3D, a finite element-bas…
View article: Locked at Both Ends: A Rare Case of Coexisting Idiopathic Hypertrophic Pyloric Stenosis and Achalasia Cardia in an Infant
Locked at Both Ends: A Rare Case of Coexisting Idiopathic Hypertrophic Pyloric Stenosis and Achalasia Cardia in an Infant Open
A BSTRACT We report a rare case of an infant diagnosed with both infantile hypertrophic pyloric stenosis and achalasia cardia, presenting significant diagnostic and therapeutic challenges. This case underscores the importance of considerin…
View article: Benzimidazole-Quinazoline Fused Derivativesvia In-Silico Study Approach Targeting GABA A Receptor for PET-based Brain Imaging
Benzimidazole-Quinazoline Fused Derivativesvia In-Silico Study Approach Targeting GABA A Receptor for PET-based Brain Imaging Open
Epilepsy is a neurological disorder that originates from an electrical imbalance in the brain. According to the data, approximately. ~50 millionpeople are affected by this disease. Exploring the epileptic region of the brain using positron…
View article: Effect of Edaravone Therapy on Amyotrophic Lateral Sclerosis Functional Rating Score (ALS-FRS) in Patients of Amyotrophic Lateral Sclerosis (ALS) in Central India: A Retrospective Open Label Study
Effect of Edaravone Therapy on Amyotrophic Lateral Sclerosis Functional Rating Score (ALS-FRS) in Patients of Amyotrophic Lateral Sclerosis (ALS) in Central India: A Retrospective Open Label Study Open
s Background Amyotrophic Lateral Sclerosis (ALS) is a progressive neurodegenerative disorder affecting motor neurons and is characterised by a diverse range of clinical manifestations. With the understanding of its pathophysiology, many tr…
View article: Congenital Rectouterine Fistula: A Rare Variety of Anorectal Malformation
Congenital Rectouterine Fistula: A Rare Variety of Anorectal Malformation Open
View article: Iron Oxide Nanoparticle Genotoxicity, ROS Production, and Epigenetic Alterations: A Comprehensive Review
Iron Oxide Nanoparticle Genotoxicity, ROS Production, and Epigenetic Alterations: A Comprehensive Review Open
This review provides an overview of the current insights into the genotoxic effects of iron oxide nanoparticles (IONPs), the mechanisms of reactive oxygen species (ROS) production, and the subsequent epigenetic alterations. With the increa…
View article: Evaluation of tomato (Solanum lycopersicum L.) genotypes for quality traits and economic feasibility under Malwa condition
Evaluation of tomato (Solanum lycopersicum L.) genotypes for quality traits and economic feasibility under Malwa condition Open
View article: Evaluation the Electronic Properties of Glu-Ureido Template via Ab-Initio Study as Target Specific for PSMA
Evaluation the Electronic Properties of Glu-Ureido Template via Ab-Initio Study as Target Specific for PSMA Open
The Prostate cancer (PC) is a major problem all over worldwide and this is the second highest cancer-related mortality rate after lung cancer all over worldwide. At least 299,010 likely cases in men were reported in the US in 2024 and abou…
View article: Development and Validation of the Stability of p-SCN-Bn-Df via the Reversed-Phase Chromatography Method: Practical Experiences
Development and Validation of the Stability of p-SCN-Bn-Df via the Reversed-Phase Chromatography Method: Practical Experiences Open
The DFO, a special hexadentate chelator with three hydroxamate moieties, is a bifunctional 1-(4-isothiocyanatophenyl)-3-[6,17-dihydroxy-7,10,18,21-tetraoxo-27-(N-acetylhydroxylamino)- 6,11,17, 22- tetraazaheptaeicosine] thiourea (p-SCN-Bn-…
View article: Evaluation Electronic Properties of Rufinamide via Ab-Initio Study as Anti-Epileptic Drug
Evaluation Electronic Properties of Rufinamide via Ab-Initio Study as Anti-Epileptic Drug Open
The FDA approved rufinamide, chemically 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide, a triazole-based scaffold, as an anticonvulsant drug in 2008. It is mainly used to treat seizures associated with Lennox–Gastaut Syndrome (LGS)…
View article: Bridging the Gap: Holistic Management of Destitute Patients in Hospital Settings: A Global and Indian Perspective
Bridging the Gap: Holistic Management of Destitute Patients in Hospital Settings: A Global and Indian Perspective Open
View article: Evaluating the Impact of Elective Endotracheal Tube Replacement on Postoperative Outcomes in Esophageal Atresia: A STROBE-guided Study
Evaluating the Impact of Elective Endotracheal Tube Replacement on Postoperative Outcomes in Esophageal Atresia: A STROBE-guided Study Open
A BSTRACT Background: Elective ventilation and paralysis have been shown to decrease the anastomosis-related complications following primary repair of esophageal atresia (EA). Repeated endotracheal tube (ETT) block and replacement can incr…
View article: Humeral Head Subluxation: An Unexpected Cause of Axillary Mass in a Child
Humeral Head Subluxation: An Unexpected Cause of Axillary Mass in a Child Open
View article: Cloacal Exstrophy with Normal Penis and Urethra – A Rare Variant
Cloacal Exstrophy with Normal Penis and Urethra – A Rare Variant Open
A BSTRACT Classically, cloacal exstrophy presents with omphalocele, bladder exstrophy, imperforate anus, and spinal defects. We report a rare variant of cloacal exstrophy in a 6-day-old male with an intact lower abdominal wall, normal peni…
View article: Congenital Segmental Dilatation of Ascending Colon with Distal Microcolon
Congenital Segmental Dilatation of Ascending Colon with Distal Microcolon Open
A 5-day-old male presented with bilious vomiting, a grossly distended abdomen, and passage of a small amount of stool. The anal opening was at a normal position. X-ray abdomen showed a large bowel loop with a single air-fluid level occupyi…
View article: Fetus-In-Fetu
Fetus-In-Fetu Open
A 7-day-old male child presented with abdominal distention and jaundice. Radiological investigations revealed an encapsulated sac encasing three fetus-in-fetu (FIF) in the retroperitoneum. Laparotomy revealed a sac occupying almost the who…
View article: Evaluation of Rhizobium along with Multifunctional Rhizobacteria for Improving the Growth and Yield of Black Gram [Vigna mungo (L.) Hepper]
Evaluation of Rhizobium along with Multifunctional Rhizobacteria for Improving the Growth and Yield of Black Gram [Vigna mungo (L.) Hepper] Open
Background: Indigenous rhizobial populations may be unable to achieve successful symbiosis in the field due to rare population and unfavourable soil environment. Introduced plant growth promoting rhizobacteria (PGPR) are frequently linked …
View article: Numerical and Experimental Examination of Novel Delta Cut Winglet
Numerical and Experimental Examination of Novel Delta Cut Winglet Open
Details of a numerical and experimental investigation on the heat transfer characteristics for three-dimensional turbulent flows in a rectangular duct with punched Delta Cut Winglet are presented in the present article. The aim of the stud…
View article: Vital dye lymphoscintigraphy: An answer to decision making between single or two-stage laparoscopic Fowler-Stephens orchidopexy intraoperatively
Vital dye lymphoscintigraphy: An answer to decision making between single or two-stage laparoscopic Fowler-Stephens orchidopexy intraoperatively Open
Introduction We hypothesized that vital dye lymphoscintigraphy (VDL) can be used to assess the testicular supply via vessel to vas and can be used to decide whether to go for single-stage Fowler-Stephens (FS1) or two-staged Fowler-Stephens…
View article: Acetylcholinesterase histochemistry: A very useful technique in the diagnosis of Hirschsprung’s disease
Acetylcholinesterase histochemistry: A very useful technique in the diagnosis of Hirschsprung’s disease Open
Hirschsprung’s disease (HD) is a common congenital paediatric disorder. The gold standard for its diagnosis is the demonstration of the absence of ganglion cells on H&E stained sections from a spastic segment of the bowel, still at times; …
View article: Evaluation of Comparative Efficacy of Jyotishmati (Celastrus paniculatus Wild) and Yastimadhu (Glycyrrhiza glabra Linn) in Enhancing IQ and Memory of Different Prakriti School Going Children-A Study Protocol of Double Blind Randomized Clinical Trial
Evaluation of Comparative Efficacy of Jyotishmati (Celastrus paniculatus Wild) and Yastimadhu (Glycyrrhiza glabra Linn) in Enhancing IQ and Memory of Different Prakriti School Going Children-A Study Protocol of Double Blind Randomized Clinical Trial Open
Background: Education plays a major role in life, whereas lack of intelligence, learning, and memory will lead to failure in school performance and school dropout. Medhya drugs are used frequently to enhance the memory and IQ in children. …
View article: Adenomatous Hyperplasia of Palatal Minor Salivary Gland and Angiolipoma of the Floor of Mouth: The First Documented Case Report in a Neonate
Adenomatous Hyperplasia of Palatal Minor Salivary Gland and Angiolipoma of the Floor of Mouth: The First Documented Case Report in a Neonate Open
View article: Does Early Treatment of Paediatric Orbital Fracture Offer Any Advantage in Terms of Post-Operative Clinical Outcomes
Does Early Treatment of Paediatric Orbital Fracture Offer Any Advantage in Terms of Post-Operative Clinical Outcomes Open
View article: Utility of Real-Time Online Teaching During COVID Era Among Surgery Postgraduates
Utility of Real-Time Online Teaching During COVID Era Among Surgery Postgraduates Open
View article: Congenital Diaphragmatic Hernia: Experience and Results of Thoracoscopic Repair from a Tertiary Care Hospital
Congenital Diaphragmatic Hernia: Experience and Results of Thoracoscopic Repair from a Tertiary Care Hospital Open
Introduction Congenital diaphragmatic hernia (CDH) is one of the most common congenital anomalies encountered by pediatric surgeons. With the advances in the pediatric minimal access surgery, its role in the repair of CDH has also increase…
View article: Active Telephonic Follow-up During COVID-19 Lockdown: Initial Experience
Active Telephonic Follow-up During COVID-19 Lockdown: Initial Experience Open
View article: Our experience with anesthetic management of conjoined twins' separation surgery
Our experience with anesthetic management of conjoined twins' separation surgery Open
Conjoined twins are one of the most fascinating human malformations. Here, we report the anesthetic management and challenges faced in performing the successful separation surgery of 4-day-old thoraco-omphalopagus conjoined twins, born at …
View article: MRI detection of posterior urethral diverticulum following surgical repair of anorectal malformations
MRI detection of posterior urethral diverticulum following surgical repair of anorectal malformations Open
Aim: To identify and to assess imaging and clinical features of Posterior urethral diverticula (PUD) in a single-centre series and include a brief review of literature. Materials and method: Post operative MRI of 140 children from north In…
View article: Simultaneous single-staged repair of anorectal malformation with tracheoesophageal fistula: Lessons learned
Simultaneous single-staged repair of anorectal malformation with tracheoesophageal fistula: Lessons learned Open
The simultaneous single-staged primary repairs result in better long-term outcome in our setup.