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View article: The immune contexture of primary central nervous system diffuse large B cell lymphoma associates with patient survival and specific cell signaling
The immune contexture of primary central nervous system diffuse large B cell lymphoma associates with patient survival and specific cell signaling Open
Rationale: Primary central nervous system diffuse large B-cell lymphoma (PCNSL) is a rare and aggressive entity that resides in an immune-privileged site. The tumor microenvironment (TME) and the disruption of the immune surveillance influ…
View article: The immune landscape of primary central nervous system diffuse large B cell lymphoma
The immune landscape of primary central nervous system diffuse large B cell lymphoma Open
Primary central nervous system diffuse large B-cell lymphoma (PCNSL) is a rare and aggressive entity that resides in an immune-privileged site. The tumor microenvironment (TME) and the disruption of the immune surveillance influence lympho…
View article: A Retrospective Comparison of DLI and gDLI for Post-Transplant Treatment
A Retrospective Comparison of DLI and gDLI for Post-Transplant Treatment Open
Donor lymphocyte infusion (DLI) is used to prevent or treat haematological malignancies relapse after allogeneic stem cell transplantation (allo-SCT). Recombinant human granulocyte colony-stimulated factor primed DLI (gDLI) is derived from…
View article: The molecular landscape and microenvironment of salivary duct carcinoma reveal new therapeutic opportunities
The molecular landscape and microenvironment of salivary duct carcinoma reveal new therapeutic opportunities Open
Purpose: Salivary duct carcinoma (SDC) is a rare and aggressive salivary gland cancer subtype with poor prognosis. The mutational landscape of SDC has already been the object of several studies, however little is known regarding the functi…
View article: The molecular landscape and microenvironment of salivary duct carcinoma reveal new therapeutic opportunities
The molecular landscape and microenvironment of salivary duct carcinoma reveal new therapeutic opportunities Open
Salivary duct carcinoma (SDC) is a rare and aggressive salivary gland cancer subtype with poor prognosis. The mutational landscape of SDC has been described rather exhaustively; yet, with respect to functional genomics and tumor microenvir…
View article: Generation of induced pluripotent stem cells (iPSCs) IRMBi002-A from an Alzheimer's disease patient carrying a D694N mutation in the APP gene
Generation of induced pluripotent stem cells (iPSCs) IRMBi002-A from an Alzheimer's disease patient carrying a D694N mutation in the APP gene Open
Induced pluripotent stem cells (iPSC) were generated from skin fibroblasts obtained from a 58 year-old woman suffering from Alzheimer's disease and carrying a D694N mutation on Amyloid precursor protein (APP). Fibroblasts were reprogrammed…
View article: Generation of induced pluripotent stem cells (IRMBi001-A) from an Alzheimer's disease patient carrying a G217D mutation in the PSEN1 gene
Generation of induced pluripotent stem cells (IRMBi001-A) from an Alzheimer's disease patient carrying a G217D mutation in the PSEN1 gene Open
Induced pluripotent stem cells (iPSC) were generated from skin fibroblasts obtained from a 50 year-old patient suffering from Alzheimer's disease and carrying a G217D causal mutation on presenilin 1 (PSEN1). iPSCs were obtained following r…