Valeria Buzzelli
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View article: Early Life Social Isolation Dysregulates Social Reward Processing, <scp>BDNF</scp> Signaling, and Intracellular Vesicular Sorting in the Nucleus Accumbens of Male and Female Rats
Early Life Social Isolation Dysregulates Social Reward Processing, <span>BDNF</span> Signaling, and Intracellular Vesicular Sorting in the Nucleus Accumbens of Male and Female Rats Open
Early‐life social deprivation negatively impacts brain development and behavior, increasing susceptibility to neuropsychiatric disorders. In social species such as rats, interactions with the mother and conspecifics are crucial for offspri…
View article: Prenatal Exposure to Lipopolysaccharide or Valproate Leads to Abnormal Accumulation of the NMDA Receptor Agonist D‐Aspartate in the Adolescent Rat Brain
Prenatal Exposure to Lipopolysaccharide or Valproate Leads to Abnormal Accumulation of the NMDA Receptor Agonist D‐Aspartate in the Adolescent Rat Brain Open
Autism spectrum disorder (ASD) is a neurodevelopmental psychiatric condition linked to glutamatergic neurotransmission disruption. Although endogenous D‐serine and D‐aspartate modulate glutamatergic N‐methyl D‐aspartate receptor (NMDAR) ac…
View article: Role of peroxisome proliferator-activated receptors α and γ in mediating the beneficial effects of β-caryophyllene in a rat model of fragile X syndrome
Role of peroxisome proliferator-activated receptors α and γ in mediating the beneficial effects of β-caryophyllene in a rat model of fragile X syndrome Open
View article: Communal nesting shapes the sex-dependent glutamatergic response to early life stress in the rat prefrontal cortex
Communal nesting shapes the sex-dependent glutamatergic response to early life stress in the rat prefrontal cortex Open
Introduction Early social environment, either positive or negative, shapes the adult brain. Communal nesting (CN), a naturalistic setting in which 2-3 females keep their pups in a single nest sharing care-giving behavior, provides high lev…
View article: Cannabidiol and positive effects on object recognition memory in an in vivo model of Fragile X Syndrome: Obligatory role of hippocampal GPR55 receptors
Cannabidiol and positive effects on object recognition memory in an in vivo model of Fragile X Syndrome: Obligatory role of hippocampal GPR55 receptors Open
View article: Outcomes of early social experiences on glucocorticoid and endocannabinoid systems in the prefrontal cortex of male and female adolescent rats
Outcomes of early social experiences on glucocorticoid and endocannabinoid systems in the prefrontal cortex of male and female adolescent rats Open
Social and emotional experiences differently shape individual’s neurodevelopment inducing substantial changes in neurobiological substrates and behavior, particularly when they occur early in life. In this scenario, the present study was a…
View article: Endocannabinoid system genes regulation in the effects evoked by social isolation in rats
Endocannabinoid system genes regulation in the effects evoked by social isolation in rats Open
Social isolation is a state of lack of social connections, involving the modulation of different molecular signalling cascades and associated with high risk of mental health issues. To investigate if and how gene expression is modulated by…
View article: Correction to: Group I and group II metabotropic glutamate receptors are upregulated in the synapses of infant rats prenatally exposed to valproic acid
Correction to: Group I and group II metabotropic glutamate receptors are upregulated in the synapses of infant rats prenatally exposed to valproic acid Open
View article: Group I and group II metabotropic glutamate receptors are upregulated in the synapses of infant rats prenatally exposed to valproic acid
Group I and group II metabotropic glutamate receptors are upregulated in the synapses of infant rats prenatally exposed to valproic acid Open
Rationale Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired social interaction and restricted/stereotyped behavior. Prenatal exposure to valproic acid (VPA) is associated with an increased risk of de…
View article: Maternal Immune Activation Induced by Prenatal Lipopolysaccharide Exposure Leads to Long-Lasting Autistic-like Social, Cognitive and Immune Alterations in Male Wistar Rats
Maternal Immune Activation Induced by Prenatal Lipopolysaccharide Exposure Leads to Long-Lasting Autistic-like Social, Cognitive and Immune Alterations in Male Wistar Rats Open
Several studies have supported the association between maternal immune activation (MIA) caused by exposure to pathogens or inflammation during critical periods of gestation and an increased susceptibility to the development of various psyc…
View article: Endocannabinoid system genes regulation in the prefrontal cortex of socially isolated rats
Endocannabinoid system genes regulation in the prefrontal cortex of socially isolated rats Open
View article: FMR1 deletion in rats induces hyperactivity with no changes in striatal dopamine transporter availability
FMR1 deletion in rats induces hyperactivity with no changes in striatal dopamine transporter availability Open
View article: Anandamide and 2-arachidonoylglycerol differentially modulate autistic-like traits in a genetic model of autism based on FMR1 deletion in rats
Anandamide and 2-arachidonoylglycerol differentially modulate autistic-like traits in a genetic model of autism based on FMR1 deletion in rats Open
View article: Regulation of oxytocin receptor gene expression in obsessive–compulsive disorder: a possible role for the microbiota-host epigenetic axis
Regulation of oxytocin receptor gene expression in obsessive–compulsive disorder: a possible role for the microbiota-host epigenetic axis Open
View article: Brain Cholesterol Biosynthetic Pathway Is Altered in a Preclinical Model of Fragile X Syndrome
Brain Cholesterol Biosynthetic Pathway Is Altered in a Preclinical Model of Fragile X Syndrome Open
Fragile X Syndrome (FXS) is the most frequent form of inherited X-linked pathology, associated with an intellectual and developmental disability, and currently considered the first monogenic cause of autism spectrum disorder (ASD). Low lev…
View article: Missense mutation of Fmr1 results in impaired AMPAR-mediated plasticity and socio-cognitive deficits in mice
Missense mutation of Fmr1 results in impaired AMPAR-mediated plasticity and socio-cognitive deficits in mice Open
View article: Detrimental effects of the ‘bath salt’ methylenedioxypyrovalerone on social play behavior in male rats
Detrimental effects of the ‘bath salt’ methylenedioxypyrovalerone on social play behavior in male rats Open
View article: Abnormal AMPAR-mediated synaptic plasticity, cognitive and autistic-like behaviors in a missense<i>Fmr1</i>mutant mouse model of Fragile X syndrome
Abnormal AMPAR-mediated synaptic plasticity, cognitive and autistic-like behaviors in a missense<i>Fmr1</i>mutant mouse model of Fragile X syndrome Open
Fragile X syndrome (FXS) is the most frequent form of inherited intellectual disability and the best-described monogenic cause of autism. FXS is usually caused by a CGG-repeat expansion in the FMR1 gene leading to its silencing and the los…